5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one

C208H219F5N20O24 — CID 157350660

IUPAC5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one
SMILESCCc1cccc(CC(=O)c2ccc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)c1.Cc1ccc(C(=O)Cc2cc(C(F)(F)F)ccn2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccc(C(C)C)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2ccccc2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2ccccn2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccnc2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1
InChIInChI=1S/C29H31N3O3.C28H32N2O3.C27H30N2O3.C26H26F2N2O3.C25H24F3N3O3.C25H26N2O3.2C24H25N3O3/c1-20-8-9-22(27(33)15-21-6-5-7-24(14-21)29(2,3)19-30)16-25(20)23-17-26(28(34)31(4)18-23)32-10-12-35-13-11-32;1-19(2)22-7-5-6-21(14-22)15-27(31)23-9-8-20(3)25(16-23)24-17-26(28(32)29(4)18-24)30-10-12-33-13-11-30;1-4-20-6-5-7-21(14-20)15-26(30)22-9-8-19(2)24(16-22)23-17-25(27(31)28(3)18-23)29-10-12-32-13-11-29;1-17-6-7-19(24(31)13-18-4-3-5-20(12-18)25(27)28)14-22(17)21-15-23(26(32)29(2)16-21)30-8-10-33-11-9-30;1-16-3-4-17(23(32)14-20-13-19(5-6-29-20)25(26,27)28)11-21(16)18-12-22(24(33)30(2)15-18)31-7-9-34-10-8-31;1-18-8-9-20(24(28)14-19-6-4-3-5-7-19)15-22(18)21-16-23(25(29)26(2)17-21)27-10-12-30-13-11-27;1-17-5-6-19(23(28)12-18-4-3-7-25-15-18)13-21(17)20-14-22(24(29)26(2)16-20)27-8-10-30-11-9-27;1-17-6-7-18(23(28)15-20-5-3-4-8-25-20)13-21(17)19-14-22(24(29)26(2)16-19)27-9-11-30-12-10-27/h5-9,14,16-18H,10-13,15H2,1-4H3;5-9,14,16-19H,10-13,15H2,1-4H3;5-9,14,16-18H,4,10-13,15H2,1-3H3;3-7,12,14-16,25H,8-11,13H2,1-2H3;3-6,11-13,15H,7-10,14H2,1-2H3;3-9,15-17H,10-14H2,1-2H3;3-7,13-16H,8-12H2,1-2H3;3-8,13-14,16H,9-12,15H2,1-2H3
InChIKeyBHMKJMHLGFZFAY-UHFFFAOYSA-N
MW3478.15 g/mol
LogP31.61
Rot. Bonds44

About 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one

5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one (PubChem CID 157350660) has the molecular formula C208H219F5N20O24 and a molecular weight of 3478.15 g/mol. Its IUPAC name is 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one.

Molecular Properties

Compound Name5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one
PubChem CID157350660
Molecular FormulaC208H219F5N20O24
Molecular Weight3478.15 g/mol
Exact Mass3475.65
IUPAC Name5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one
SMILESCCc1cccc(CC(=O)c2ccc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)c1.Cc1ccc(C(=O)Cc2cc(C(F)(F)F)ccn2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccc(C(C)C)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2ccccc2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2ccccn2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccnc2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1
InChIInChI=1S/C29H31N3O3.C28H32N2O3.C27H30N2O3.C26H26F2N2O3.C25H24F3N3O3.C25H26N2O3.2C24H25N3O3/c1-20-8-9-22(27(33)15-21-6-5-7-24(14-21)29(2,3)19-30)16-25(20)23-17-26(28(34)31(4)18-23)32-10-12-35-13-11-32;1-19(2)22-7-5-6-21(14-22)15-27(31)23-9-8-20(3)25(16-23)24-17-26(28(32)29(4)18-24)30-10-12-33-13-11-30;1-4-20-6-5-7-21(14-20)15-26(30)22-9-8-19(2)24(16-22)23-17-25(27(31)28(3)18-23)29-10-12-32-13-11-29;1-17-6-7-19(24(31)13-18-4-3-5-20(12-18)25(27)28)14-22(17)21-15-23(26(32)29(2)16-21)30-8-10-33-11-9-30;1-16-3-4-17(23(32)14-20-13-19(5-6-29-20)25(26,27)28)11-21(16)18-12-22(24(33)30(2)15-18)31-7-9-34-10-8-31;1-18-8-9-20(24(28)14-19-6-4-3-5-7-19)15-22(18)21-16-23(25(29)26(2)17-21)27-10-12-30-13-11-27;1-17-5-6-19(23(28)12-18-4-3-7-25-15-18)13-21(17)20-14-22(24(29)26(2)16-20)27-8-10-30-11-9-27;1-17-6-7-18(23(28)15-20-5-3-4-8-25-20)13-21(17)19-14-22(24(29)26(2)16-19)27-9-11-30-12-10-27/h5-9,14,16-18H,10-13,15H2,1-4H3;5-9,14,16-19H,10-13,15H2,1-4H3;5-9,14,16-18H,4,10-13,15H2,1-3H3;3-7,12,14-16,25H,8-11,13H2,1-2H3;3-6,11-13,15H,7-10,14H2,1-2H3;3-9,15-17H,10-14H2,1-2H3;3-7,13-16H,8-12H2,1-2H3;3-8,13-14,16H,9-12,15H2,1-2H3
InChIKeyBHMKJMHLGFZFAY-UHFFFAOYSA-N
XLogP31.61
TPSA474.78 Ų
H-Bond Donors
H-Bond Acceptors44
Rotatable Bonds44
Heavy Atoms257
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003478.15
LogP ≤ 531.61
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1044

Analyze 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one with MolForge

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Launch Full Analysis

Related Compounds

3-(2-cyanopropan-2-yl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]benzamide;3-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]benzamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]-2-[(2S)-oxolan-2-yl]acetamide;N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157282373
3-(cyanomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]benzamide;2-cyclopropyl-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]benzamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-methyl-6-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-4-morpholin-4-ylpyridazin-3-one
CID 157402875
1-(2-Fluorophenyl)-4-pyridin-2-ylbutane-1,4-dione;1-(2-methylphenyl)-4-pyridin-2-ylbutane-1,4-dione;tris(1-(3-methylphenyl)-4-pyridin-2-ylbutane-1,4-dione);tris(1-(4-methylphenyl)-4-pyridin-2-ylbutane-1,4-dione);1-pyridin-2-yl-4-[2-(trifluoromethyl)phenyl]butane-1,4-dione
CID 157779804
2-tert-butyl-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;N-[3-[1-(2-hydroxyethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
CID 157816318
2-(1-cyanocyclopropyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;3-(cyanomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]benzamide;2-cyclopropyl-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]benzamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-methyl-6-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-4-morpholin-4-ylpyridazin-3-one
CID 157935136
2-(2-cyanopropan-2-yl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;N-[3-[4-(2,2-difluoroethyl)-6-morpholin-4-yl-5-oxopyrazin-2-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-(4-ethyl-6-morpholin-4-yl-5-oxopyrazin-2-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 158353972
N-[4-[4-[2-(benzylamino)-2-oxo-1-phenylethyl]piperidin-1-yl]phenyl]-2-(4-tert-butylphenyl)benzamide;N-[4-[4-[2-(ethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl]phenyl]-2-[4-(trifluoromethyl)phenyl]benzamide;N-[4-[4-[2-oxo-1-phenyl-2-(prop-2-enylamino)ethyl]piperazin-1-yl]phenyl]-2-[4-(trifluoromethyl)phenyl]benzamide;N-[4-[4-[2-oxo-1-phenyl-2-(pyridin-2-ylmethylamino)ethyl]piperazin-1-yl]phenyl]-2-[4-(trifluoromethyl)phenyl]benzamide;N-[4-[4-[2-oxo-1-phenyl-2-(pyridin-3-ylmethylamino)ethyl]piperazin-1-yl]phenyl]-2-[4-(trifluoromethyl)phenyl]benzamide
CID 158597924
2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide
CID 158959062
N-[3-[1-(2-cyanoethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-4-methylphenyl]-2-(2-cyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[1-(2-cyanoethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-4-methylphenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;N-[3-[1-(2-cyanoethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-4-methylphenyl]-3-(difluoromethyl)benzamide;N-[5-[1-(2-cyanoethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-[(3-methyloxetan-3-yl)methyl]-5-morpholin-4-yl-6-oxo-3-pyridinyl]phenyl]pyridine-3-carboxamide;N-[4-methyl-3-[1-[(3-methyloxetan-3-yl)methyl]-5-morpholin-4-yl-6-oxo-3-pyridinyl]phenyl]-3-(trifluoromethyl)benzamide
CID 159760817
2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-(oxan-4-yl)-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoropropyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-(oxan-4-yl)-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide
CID 159878519
5-(3-acetylphenyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyridine-2-carboxamide;5-(3-cyanophenyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyridine-2-carboxamide;5-[3-(dimethylamino)phenyl]-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyridine-2-carboxamide;5-(3-fluorophenyl)-N-[[6-(2-fluoro-4-pyridinyl)-5-methyl-3-pyridinyl]methyl]pyridine-2-carboxamide;5-(3-fluorophenyl)-N-[[5-methyl-6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyridine-2-carboxamide;5-(4-fluorophenyl)-N-[[6-(2-methyl-4-pyridinyl)-3-pyridinyl]methyl]pyridine-2-carboxamide;5-(3-fluorophenyl)-N-[[6-[2-(trifluoromethyl)-4-pyridinyl]-3-pyridinyl]methyl]pyridine-2-carboxamide
CID 159907883
N-[3-[1-(2-cyanoethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-4-methylphenyl]-2-(2-cyanopropan-2-yl)pyridine-4-carboxamide;N-[3-[1-(2-cyanoethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-4-methylphenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;N-[3-[1-(2-cyanoethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-4-methylphenyl]-3-(difluoromethyl)benzamide;N-[5-[1-(2-cyanoethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-(2-cyanopropan-2-yl)-N-[5-(1-ethyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;methane;N-[4-methyl-3-[1-[(3-methyloxetan-3-yl)methyl]-5-morpholin-4-yl-6-oxo-3-pyridinyl]phenyl]-3-(trifluoromethyl)benzamide
CID 160041522

Frequently Asked Questions

What is the IUPAC name of 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one?
The IUPAC name of 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one (CID 157350660) is 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one.
What is the SMILES notation for 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one?
The canonical SMILES for 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one is CCc1cccc(CC(=O)c2ccc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)c1.Cc1ccc(C(=O)Cc2cc(C(F)(F)F)ccn2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccc(C(C)C)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccc(C(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2ccccc2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2ccccn2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(C(=O)Cc2cccnc2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.
What is the InChIKey of 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one?
The InChIKey is BHMKJMHLGFZFAY-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H31N3O3.C28H32N2O3.C27H30N2O3.C26H26F2N2O3.C25H24F3N3O3.C25H26N2O3.2C24H25N3O3/c1-20-8-9-22(27(33)15-21-6-5-7-24(14-21)29(2,3)19-30)16-25(20)23-17-26(28(34)31(4)18-23)32-10-12-35-13-11-32;1-19(2)22-7-5-6-21(14-22)15-27(31)23-9-8-20(3)25(16-23)24-17-26(28(32)29(4)18-24)30-10-12-33-13-11-30;1-4-20-6-5-7-21(14-20)15-26(30)22-9-8-19(2)24(16-22)23-17-25(27(31)28(3)18-23)29-10-12-32-13-11-29;1-17-6-7-19(24(31)13-18-4-3-5-20(12-18)25(27)28)14-22(17)21-15-23(26(32)29(2)16-21)30-8-10-33-11-9-30;1-16-3-4-17(23(32)14-20-13-19(5-6-29-20)25(26,27)28)11-21(16)18-12-22(24(33)30(2)15-18)31-7-9-34-10-8-31;1-18-8-9-20(24(28)14-19-6-4-3-5-7-19)15-22(18)21-16-23(25(29)26(2)17-21)27-10-12-30-13-11-27;1-17-5-6-19(23(28)12-18-4-3-7-25-15-18)13-21(17)20-14-22(24(29)26(2)16-20)27-8-10-30-11-9-27;1-17-6-7-18(23(28)15-20-5-3-4-8-25-20)13-21(17)19-14-22(24(29)26(2)16-19)27-9-11-30-12-10-27/h5-9,14,16-18H,10-13,15H2,1-4H3;5-9,14,16-19H,10-13,15H2,1-4H3;5-9,14,16-18H,4,10-13,15H2,1-3H3;3-7,12,14-16,25H,8-11,13H2,1-2H3;3-6,11-13,15H,7-10,14H2,1-2H3;3-9,15-17H,10-14H2,1-2H3;3-7,13-16H,8-12H2,1-2H3;3-8,13-14,16H,9-12,15H2,1-2H3.
What are the key properties of 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one?
5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one has a molecular weight of 3478.15 g/mol, XLogP of 31.61, 44 rotatable bonds, 0 hydrogen bond donors, and 44 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[5-[2-[3-(difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one is sourced from PubChem (CID 157350660), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).