2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide

C185H210F7N37O21 — CID 158959062

IUPAC2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide
SMILESCc1ccc(NC(=O)c2cc(CN(C)C)cc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOC(C)(C)C2)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOC[C@@H]2C)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cc(N2CCOC(C)(C)C2)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cc(N2CCOC[C@@H]2C)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOC[C@@H]2C)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)C)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)n1
InChIInChI=1S/C28H32N6O3.C27H30F3N5O3.C27H32FN5O3.C27H30N6O3.C26H30FN5O3.C25H27F2N5O3.C25H29N5O3/c1-18-7-8-20(31-25(35)19-9-10-30-24(13-19)27(2,3)16-29)14-21(18)22-15-23(26(36)33(6)32-22)34-11-12-37-28(4,5)17-34;1-17-5-6-21(31-25(36)19-11-18(16-33(2)3)12-20(13-19)27(28,29)30)14-22(17)23-15-24(26(37)34(4)32-23)35-7-9-38-10-8-35;1-17-7-8-19(30-24(34)18-9-10-29-23(13-18)27(4,5)28)14-20(17)21-15-22(25(35)32(6)31-21)33-11-12-36-26(2,3)16-33;1-17-6-7-20(30-25(34)19-8-9-29-24(12-19)27(3,4)16-28)13-21(17)22-14-23(26(35)32(5)31-22)33-10-11-36-15-18(33)2;1-16-6-7-19(29-24(33)18-8-9-28-23(12-18)26(3,4)27)13-20(16)21-14-22(25(34)31(5)30-21)32-10-11-35-15-17(32)2;1-15-5-6-18(29-23(33)17-7-8-28-22(11-17)25(3,26)27)12-19(15)20-13-21(24(34)31(4)30-20)32-9-10-35-14-16(32)2;1-16(2)21-13-18(7-8-26-21)24(31)27-19-6-5-17(3)20(14-19)22-15-23(25(32)29(4)28-22)30-9-11-33-12-10-30/h7-10,13-15H,11-12,17H2,1-6H3,(H,31,35);5-6,11-15H,7-10,16H2,1-4H3,(H,31,36);7-10,13-15H,11-12,16H2,1-6H3,(H,30,34);6-9,12-14,18H,10-11,15H2,1-5H3,(H,30,34);6-9,12-14,17H,10-11,15H2,1-5H3,(H,29,33);5-8,11-13,16H,9-10,14H2,1-4H3,(H,29,33);5-8,13-16H,9-12H2,1-4H3,(H,27,31)/t;;;18-;17-;16-;/m...000./s1
InChIKeyJMJQRXKCQICIPB-CLFPZJGXSA-N
MW3420.94 g/mol
LogP26.33
Rot. Bonds36

About 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide

2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide (PubChem CID 158959062) has the molecular formula C185H210F7N37O21 and a molecular weight of 3420.94 g/mol. Its IUPAC name is 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide.

Molecular Properties

Compound Name2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide
PubChem CID158959062
Molecular FormulaC185H210F7N37O21
Molecular Weight3420.94 g/mol
Exact Mass3418.64
IUPAC Name2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide
SMILESCc1ccc(NC(=O)c2cc(CN(C)C)cc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOC(C)(C)C2)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOC[C@@H]2C)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cc(N2CCOC(C)(C)C2)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cc(N2CCOC[C@@H]2C)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOC[C@@H]2C)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)C)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)n1
InChIInChI=1S/C28H32N6O3.C27H30F3N5O3.C27H32FN5O3.C27H30N6O3.C26H30FN5O3.C25H27F2N5O3.C25H29N5O3/c1-18-7-8-20(31-25(35)19-9-10-30-24(13-19)27(2,3)16-29)14-21(18)22-15-23(26(36)33(6)32-22)34-11-12-37-28(4,5)17-34;1-17-5-6-21(31-25(36)19-11-18(16-33(2)3)12-20(13-19)27(28,29)30)14-22(17)23-15-24(26(37)34(4)32-23)35-7-9-38-10-8-35;1-17-7-8-19(30-24(34)18-9-10-29-23(13-18)27(4,5)28)14-20(17)21-15-22(25(35)32(6)31-21)33-11-12-36-26(2,3)16-33;1-17-6-7-20(30-25(34)19-8-9-29-24(12-19)27(3,4)16-28)13-21(17)22-14-23(26(35)32(5)31-22)33-10-11-36-15-18(33)2;1-16-6-7-19(29-24(33)18-8-9-28-23(12-18)26(3,4)27)13-20(16)21-14-22(25(34)31(5)30-21)32-10-11-35-15-17(32)2;1-15-5-6-18(29-23(33)17-7-8-28-22(11-17)25(3,26)27)12-19(15)20-13-21(24(34)31(4)30-20)32-9-10-35-14-16(32)2;1-16(2)21-13-18(7-8-26-21)24(31)27-19-6-5-17(3)20(14-19)22-15-23(25(32)29(4)28-22)30-9-11-33-12-10-30/h7-10,13-15H,11-12,17H2,1-6H3,(H,31,35);5-6,11-15H,7-10,16H2,1-4H3,(H,31,36);7-10,13-15H,11-12,16H2,1-6H3,(H,30,34);6-9,12-14,18H,10-11,15H2,1-5H3,(H,30,34);6-9,12-14,17H,10-11,15H2,1-5H3,(H,29,33);5-8,11-13,16H,9-10,14H2,1-4H3,(H,29,33);5-8,13-16H,9-12H2,1-4H3,(H,27,31)/t;;;18-;17-;16-;/m...000./s1
InChIKeyJMJQRXKCQICIPB-CLFPZJGXSA-N
XLogP26.33
TPSA663.38 Ų
H-Bond Donors7
H-Bond Acceptors51
Rotatable Bonds36
Heavy Atoms250
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003420.94
LogP ≤ 526.33
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1051

Analyze 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

4-(2-cyanopropan-2-yl)-N-[3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-4-[2-[3-[2-methyl-5-[[5-(trifluoromethyl)pyridine-3-carbonyl]amino]phenyl]-5-morpholin-4-yl-6-oxopyridazin-1-yl]ethyl]phenyl]pyridine-2-carboxamide
CID 130425779
2-tert-butyl-N-[3-(2,6-dimorpholin-4-ylpyrimidin-4-yl)-4-methylphenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;3-(4-ethylpiperazin-1-yl)-N-[4-methyl-3-(2-morpholin-4-yl-4-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;1-[4-methyl-3-(4-morpholin-4-yl-2-pyridinyl)phenyl]-2-[3-(trifluoromethyl)phenyl]ethanone
CID 157217069
3-(2-cyanopropan-2-yl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]benzamide;3-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]benzamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]benzamide;2-(difluoromethyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]-2-[(2S)-oxolan-2-yl]acetamide;N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157282373
5-[5-[2-[3-(Difluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;5-[5-[2-(3-ethylphenyl)acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-methyl-2-[3-[2-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-2-oxoethyl]phenyl]propanenitrile;1-methyl-5-[2-methyl-5-(2-phenylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-(3-propan-2-ylphenyl)acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-2-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-(2-pyridin-3-ylacetyl)phenyl]-3-morpholin-4-ylpyridin-2-one;1-methyl-5-[2-methyl-5-[2-[4-(trifluoromethyl)-2-pyridinyl]acetyl]phenyl]-3-morpholin-4-ylpyridin-2-one
CID 157350660
3-(cyanomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]benzamide;2-cyclopropyl-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]benzamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-methyl-6-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-4-morpholin-4-ylpyridazin-3-one
CID 157402875
CID 157415303
CID 157415303
N-[3-(2-amino-6-morpholin-4-yl-4-pyridinyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-(6-amino-4-morpholin-4-yl-2-pyridinyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157748921
6-(2-cyanopropan-2-yl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridazine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;3-(4-ethylpiperazin-1-yl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-(oxetan-3-yl)pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157792271
2-tert-butyl-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-3-pyridinyl]pyridine-4-carboxamide;N-[3-[1-(2-hydroxyethyl)-5-morpholin-4-yl-6-oxo-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
CID 157816318
2-(1-cyanocyclopropyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;3-(cyanomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]benzamide;2-cyclopropyl-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]benzamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-methyl-6-[2-methyl-5-[2-[3-(trifluoromethyl)phenyl]acetyl]phenyl]-4-morpholin-4-ylpyridazin-3-one
CID 157935136
2-(1-cyanocyclopropyl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;N-[5-(4-cyano-3-morpholin-4-ylphenyl)-6-methyl-3-pyridinyl]-3-[(dimethylamino)methyl]-5-(trifluoromethyl)benzamide;N-[5-(4-cyano-3-morpholin-4-ylphenyl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-(4-cyano-3-morpholin-4-ylphenyl)-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-cyclopropyl-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-4-morpholin-4-yl-6-oxo-2-pyridinyl)phenyl]pyridine-4-carboxamide;N-[6-methyl-5-(4-methylsulfonyl-3-morpholin-4-ylphenyl)-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 158181326
2-(2-cyanopropan-2-yl)-N-[6-methyl-5-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;N-[3-[4-(2,2-difluoroethyl)-6-morpholin-4-yl-5-oxopyrazin-2-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-(4-ethyl-6-morpholin-4-yl-5-oxopyrazin-2-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 158353972

Frequently Asked Questions

What is the IUPAC name of 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide?
The IUPAC name of 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide (CID 158959062) is 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide.
What is the SMILES notation for 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide?
The canonical SMILES for 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide is Cc1ccc(NC(=O)c2cc(CN(C)C)cc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOC(C)(C)C2)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)C#N)c2)cc1-c1cc(N2CCOC[C@@H]2C)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cc(N2CCOC(C)(C)C2)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cc(N2CCOC[C@@H]2C)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOC[C@@H]2C)c(=O)n(C)n1.Cc1ccc(NC(=O)c2ccnc(C(C)C)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)n1.
What is the InChIKey of 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide?
The InChIKey is JMJQRXKCQICIPB-CLFPZJGXSA-N. The full InChI is InChI=1S/C28H32N6O3.C27H30F3N5O3.C27H32FN5O3.C27H30N6O3.C26H30FN5O3.C25H27F2N5O3.C25H29N5O3/c1-18-7-8-20(31-25(35)19-9-10-30-24(13-19)27(2,3)16-29)14-21(18)22-15-23(26(36)33(6)32-22)34-11-12-37-28(4,5)17-34;1-17-5-6-21(31-25(36)19-11-18(16-33(2)3)12-20(13-19)27(28,29)30)14-22(17)23-15-24(26(37)34(4)32-23)35-7-9-38-10-8-35;1-17-7-8-19(30-24(34)18-9-10-29-23(13-18)27(4,5)28)14-20(17)21-15-22(25(35)32(6)31-21)33-11-12-36-26(2,3)16-33;1-17-6-7-20(30-25(34)19-8-9-29-24(12-19)27(3,4)16-28)13-21(17)22-14-23(26(35)32(5)31-22)33-10-11-36-15-18(33)2;1-16-6-7-19(29-24(33)18-8-9-28-23(12-18)26(3,4)27)13-20(16)21-14-22(25(34)31(5)30-21)32-10-11-35-15-17(32)2;1-15-5-6-18(29-23(33)17-7-8-28-22(11-17)25(3,26)27)12-19(15)20-13-21(24(34)31(4)30-20)32-9-10-35-14-16(32)2;1-16(2)21-13-18(7-8-26-21)24(31)27-19-6-5-17(3)20(14-19)22-15-23(25(32)29(4)28-22)30-9-11-33-12-10-30/h7-10,13-15H,11-12,17H2,1-6H3,(H,31,35);5-6,11-15H,7-10,16H2,1-4H3,(H,31,36);7-10,13-15H,11-12,16H2,1-6H3,(H,30,34);6-9,12-14,18H,10-11,15H2,1-5H3,(H,30,34);6-9,12-14,17H,10-11,15H2,1-5H3,(H,29,33);5-8,11-13,16H,9-10,14H2,1-4H3,(H,29,33);5-8,13-16H,9-12H2,1-4H3,(H,27,31)/t;;;18-;17-;16-;/m...000./s1.
What are the key properties of 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide?
2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide has a molecular weight of 3420.94 g/mol, XLogP of 26.33, 36 rotatable bonds, 7 hydrogen bond donors, and 51 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(2-cyanopropan-2-yl)-N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-5-(trifluoromethyl)benzamide;N-[3-[5-(2,2-dimethylmorpholin-4-yl)-1-methyl-6-oxopyridazin-3-yl]-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[4-methyl-3-[1-methyl-5-[(3S)-3-methylmorpholin-4-yl]-6-oxopyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]-2-propan-2-ylpyridine-4-carboxamide is sourced from PubChem (CID 158959062), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).