2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone

C112H121F10N27O8 — CID 157352557

IUPAC2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone
SMILESCC1(C)CCC(COCC(=O)c2c(N)nn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)O1.CCC(C)(C)OCC(=O)c1c(N)nn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.CCCNC(=O)c1c(N)nn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.CN(C)C(=O)c1c(N)nn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.Cc1ccc(CC(=O)c2c(N)nn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)cc1
InChIInChI=1S/C25H29F2N5O3.C25H23F2N5O.C23H27F2N5O2.C20H22F2N6O.C19H20F2N6O/c1-25(2)9-7-16(35-25)13-34-14-20(33)22-23(28)30-32-11-8-21(29-24(22)32)31-10-3-4-19(31)17-12-15(26)5-6-18(17)27;1-15-4-6-16(7-5-15)13-21(33)23-24(28)30-32-12-10-22(29-25(23)32)31-11-2-3-20(31)18-14-17(26)8-9-19(18)27;1-4-23(2,3)32-13-18(31)20-21(26)28-30-11-9-19(27-22(20)30)29-10-5-6-17(29)15-12-14(24)7-8-16(15)25;1-2-8-24-20(29)17-18(23)26-28-10-7-16(25-19(17)28)27-9-3-4-15(27)13-11-12(21)5-6-14(13)22;1-25(2)19(28)16-17(22)24-27-9-7-15(23-18(16)27)26-8-3-4-14(26)12-10-11(20)5-6-13(12)21/h5-6,8,11-12,16,19H,3-4,7,9-10,13-14H2,1-2H3,(H2,28,30);4-10,12,14,20H,2-3,11,13H2,1H3,(H2,28,30);7-9,11-12,17H,4-6,10,13H2,1-3H3,(H2,26,28);5-7,10-11,15H,2-4,8-9H2,1H3,(H2,23,26)(H,24,29);5-7,9-10,14H,3-4,8H2,1-2H3,(H2,22,24)/t16?,19-;20-;17-;15-;14-/m11111/s1
InChIKeyBHRZORKXEALJHU-ZFLNRYQGSA-N
MW2163.36 g/mol
LogP18.78
Rot. Bonds27

About 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone

2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone (PubChem CID 157352557) has the molecular formula C112H121F10N27O8 and a molecular weight of 2163.36 g/mol. Its IUPAC name is 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone.

Molecular Properties

Compound Name2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone
PubChem CID157352557
Molecular FormulaC112H121F10N27O8
Molecular Weight2163.36 g/mol
Exact Mass2161.97
IUPAC Name2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone
SMILESCC1(C)CCC(COCC(=O)c2c(N)nn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)O1.CCC(C)(C)OCC(=O)c1c(N)nn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.CCCNC(=O)c1c(N)nn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.CN(C)C(=O)c1c(N)nn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.Cc1ccc(CC(=O)c2c(N)nn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)cc1
InChIInChI=1S/C25H29F2N5O3.C25H23F2N5O.C23H27F2N5O2.C20H22F2N6O.C19H20F2N6O/c1-25(2)9-7-16(35-25)13-34-14-20(33)22-23(28)30-32-11-8-21(29-24(22)32)31-10-3-4-19(31)17-12-15(26)5-6-18(17)27;1-15-4-6-16(7-5-15)13-21(33)23-24(28)30-32-12-10-22(29-25(23)32)31-11-2-3-20(31)18-14-17(26)8-9-19(18)27;1-4-23(2,3)32-13-18(31)20-21(26)28-30-11-9-19(27-22(20)30)29-10-5-6-17(29)15-12-14(24)7-8-16(15)25;1-2-8-24-20(29)17-18(23)26-28-10-7-16(25-19(17)28)27-9-3-4-15(27)13-11-12(21)5-6-14(13)22;1-25(2)19(28)16-17(22)24-27-9-7-15(23-18(16)27)26-8-3-4-14(26)12-10-11(20)5-6-13(12)21/h5-6,8,11-12,16,19H,3-4,7,9-10,13-14H2,1-2H3,(H2,28,30);4-10,12,14,20H,2-3,11,13H2,1H3,(H2,28,30);7-9,11-12,17H,4-6,10,13H2,1-3H3,(H2,26,28);5-7,10-11,15H,2-4,8-9H2,1H3,(H2,23,26)(H,24,29);5-7,9-10,14H,3-4,8H2,1-2H3,(H2,22,24)/t16?,19-;20-;17-;15-;14-/m11111/s1
InChIKeyBHRZORKXEALJHU-ZFLNRYQGSA-N
XLogP18.78
TPSA425.56 Ų
H-Bond Donors6
H-Bond Acceptors33
Rotatable Bonds27
Heavy Atoms157
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002163.36
LogP ≤ 518.78
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1033

Analyze 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone with MolForge

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Related Compounds

2-amino-5-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 139449662
2-amino-5-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-[2-(dimethylamino)ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 139449642
2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-[2-(dimethylamino)ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 134480328
fluoro 2-amino-5-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
CID 166763914
5-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]-2-(ethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CID 139449700
5-[(2S)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-2-[(4-methoxyphenyl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 139449663
5-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]-2-[(4-methoxyphenyl)methylamino]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 134480598
2-amino-5-[2-(5-fluoro-2-propylphenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carbothioamide
CID 139455205
5-[2-(2,5-difluorophenyl)pyrrolidin-1-yl]-2-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CID 139449703
5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-[[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy]pyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 86664577
5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-2-(2-morpholin-4-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CID 139449691
ethyl 5-[(2R)-2-(5-fluoro-2-propylphenyl)pyrrolidin-1-yl]-2-(2-morpholin-4-ylethylamino)pyrazolo[1,5-a]pyrimidine-3-carboxylate
CID 139455204

Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone?
The IUPAC name of 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone (CID 157352557) is 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone.
What is the SMILES notation for 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone?
The canonical SMILES for 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone is CC1(C)CCC(COCC(=O)c2c(N)nn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)O1.CCC(C)(C)OCC(=O)c1c(N)nn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.CCCNC(=O)c1c(N)nn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.CN(C)C(=O)c1c(N)nn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.Cc1ccc(CC(=O)c2c(N)nn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)cc1.
What is the InChIKey of 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone?
The InChIKey is BHRZORKXEALJHU-ZFLNRYQGSA-N. The full InChI is InChI=1S/C25H29F2N5O3.C25H23F2N5O.C23H27F2N5O2.C20H22F2N6O.C19H20F2N6O/c1-25(2)9-7-16(35-25)13-34-14-20(33)22-23(28)30-32-11-8-21(29-24(22)32)31-10-3-4-19(31)17-12-15(26)5-6-18(17)27;1-15-4-6-16(7-5-15)13-21(33)23-24(28)30-32-12-10-22(29-25(23)32)31-11-2-3-20(31)18-14-17(26)8-9-19(18)27;1-4-23(2,3)32-13-18(31)20-21(26)28-30-11-9-19(27-22(20)30)29-10-5-6-17(29)15-12-14(24)7-8-16(15)25;1-2-8-24-20(29)17-18(23)26-28-10-7-16(25-19(17)28)27-9-3-4-15(27)13-11-12(21)5-6-14(13)22;1-25(2)19(28)16-17(22)24-27-9-7-15(23-18(16)27)26-8-3-4-14(26)12-10-11(20)5-6-13(12)21/h5-6,8,11-12,16,19H,3-4,7,9-10,13-14H2,1-2H3,(H2,28,30);4-10,12,14,20H,2-3,11,13H2,1H3,(H2,28,30);7-9,11-12,17H,4-6,10,13H2,1-3H3,(H2,26,28);5-7,10-11,15H,2-4,8-9H2,1H3,(H2,23,26)(H,24,29);5-7,9-10,14H,3-4,8H2,1-2H3,(H2,22,24)/t16?,19-;20-;17-;15-;14-/m11111/s1.
What are the key properties of 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone?
2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone has a molecular weight of 2163.36 g/mol, XLogP of 18.78, 27 rotatable bonds, 6 hydrogen bond donors, and 33 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N,N-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-N-propylpyrazolo[1,5-a]pyrimidine-3-carboxamide;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-[(5,5-dimethyloxolan-2-yl)methoxy]ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(2-methylbutan-2-yloxy)ethanone;1-[2-amino-5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-2-(4-methylphenyl)ethanone is sourced from PubChem (CID 157352557), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).