(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one

C159H160F10N18O13 — CID 157373192

IUPAC(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one
SMILESCC1(C)CC[C@@](C)(c2cc(F)cc(F)c2)N(C/C=C/c2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C1=O.CC1(C)CC[C@@](C)(c2cc(F)cc(F)c2)N(CCCc2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C1=O.CC1(C)NC[C@@](C)(c2cc(F)cc(F)c2)N(CCOc2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C1=O.CN1C[C@@](C)(c2cc(F)cc(F)c2)N(CCOc2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C(=O)C12CCCC2.C[C@@]1(c2cc(F)cc(F)c2)CNC2(CCCC2)C(=O)N1CCOc1ccc2c(c1)C[C@@]1(C2)C(=O)Nc2ncccc21
InChIInChI=1S/C33H34F2N4O3.C32H32F2N4O3.C32H33F2N3O2.C32H31F2N3O2.C30H30F2N4O3/c1-31(23-15-24(34)17-25(35)16-23)20-38(2)33(9-3-4-10-33)30(41)39(31)12-13-42-26-8-7-21-18-32(19-22(21)14-26)27-6-5-11-36-28(27)37-29(32)40;1-30(22-14-23(33)16-24(34)15-22)19-36-32(8-2-3-9-32)29(40)38(30)11-12-41-25-7-6-20-17-31(18-21(20)13-25)26-5-4-10-35-27(26)37-28(31)39;2*1-30(2)10-11-31(3,23-15-24(33)17-25(34)16-23)37(29(30)39)13-5-6-20-8-9-21-18-32(19-22(21)14-20)26-7-4-12-35-27(26)36-28(32)38;1-28(2)27(38)36(29(3,17-34-28)20-12-21(31)14-22(32)13-20)9-10-39-23-7-6-18-15-30(16-19(18)11-23)24-5-4-8-33-25(24)35-26(30)37/h5-8,11,14-17H,3-4,9-10,12-13,18-20H2,1-2H3,(H,36,37,40);4-7,10,13-16,36H,2-3,8-9,11-12,17-19H2,1H3,(H,35,37,39);4,7-9,12,14-17H,5-6,10-11,13,18-19H2,1-3H3,(H,35,36,38);4-9,12,14-17H,10-11,13,18-19H2,1-3H3,(H,35,36,38);4-8,11-14,34H,9-10,15-17H2,1-3H3,(H,33,35,37)/b;;;6-5+;/t31-,32+;30-,31+;2*31-,32+;29-,30+/m00000/s1
InChIKeyBJZVSWVWZAUXPH-GXUJBRKLSA-N
MW2721.12 g/mol
LogP24.74
Rot. Bonds24

About (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one

(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one (PubChem CID 157373192) has the molecular formula C159H160F10N18O13 and a molecular weight of 2721.12 g/mol. Its IUPAC name is (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one.

Molecular Properties

Compound Name(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one
PubChem CID157373192
Molecular FormulaC159H160F10N18O13
Molecular Weight2721.12 g/mol
Exact Mass2719.23
IUPAC Name(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one
SMILESCC1(C)CC[C@@](C)(c2cc(F)cc(F)c2)N(C/C=C/c2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C1=O.CC1(C)CC[C@@](C)(c2cc(F)cc(F)c2)N(CCCc2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C1=O.CC1(C)NC[C@@](C)(c2cc(F)cc(F)c2)N(CCOc2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C1=O.CN1C[C@@](C)(c2cc(F)cc(F)c2)N(CCOc2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C(=O)C12CCCC2.C[C@@]1(c2cc(F)cc(F)c2)CNC2(CCCC2)C(=O)N1CCOc1ccc2c(c1)C[C@@]1(C2)C(=O)Nc2ncccc21
InChIInChI=1S/C33H34F2N4O3.C32H32F2N4O3.C32H33F2N3O2.C32H31F2N3O2.C30H30F2N4O3/c1-31(23-15-24(34)17-25(35)16-23)20-38(2)33(9-3-4-10-33)30(41)39(31)12-13-42-26-8-7-21-18-32(19-22(21)14-26)27-6-5-11-36-28(27)37-29(32)40;1-30(22-14-23(33)16-24(34)15-22)19-36-32(8-2-3-9-32)29(40)38(30)11-12-41-25-7-6-20-17-31(18-21(20)13-25)26-5-4-10-35-27(26)37-28(31)39;2*1-30(2)10-11-31(3,23-15-24(33)17-25(34)16-23)37(29(30)39)13-5-6-20-8-9-21-18-32(19-22(21)14-20)26-7-4-12-35-27(26)36-28(32)38;1-28(2)27(38)36(29(3,17-34-28)20-12-21(31)14-22(32)13-20)9-10-39-23-7-6-18-15-30(16-19(18)11-23)24-5-4-8-33-25(24)35-26(30)37/h5-8,11,14-17H,3-4,9-10,12-13,18-20H2,1-2H3,(H,36,37,40);4-7,10,13-16,36H,2-3,8-9,11-12,17-19H2,1H3,(H,35,37,39);4,7-9,12,14-17H,5-6,10-11,13,18-19H2,1-3H3,(H,35,36,38);4-9,12,14-17H,10-11,13,18-19H2,1-3H3,(H,35,36,38);4-8,11-14,34H,9-10,15-17H2,1-3H3,(H,33,35,37)/b;;;6-5+;/t31-,32+;30-,31+;2*31-,32+;29-,30+/m00000/s1
InChIKeyBJZVSWVWZAUXPH-GXUJBRKLSA-N
XLogP24.74
TPSA366.49 Ų
H-Bond Donors7
H-Bond Acceptors21
Rotatable Bonds24
Heavy Atoms200
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002721.12
LogP ≤ 524.74
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1021

Analyze (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one with MolForge

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Related Compounds

(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one
CID 44468855
(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one
CID 44468857
[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl] 2-[(8R)-8-[4-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-9-[2-oxo-2-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]oxyethyl]-6,9-diazaspiro[4.5]decan-3-yl]-3,5-difluorophenyl]-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]acetate
CID 143869624
CID 157999425
CID 157999425
benzyl (5R,8S)-8-(3,5-difluorophenyl)-10-oxo-9-[2-oxo-2-[[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]amino]ethyl]-1,9-diazaspiro[4.5]decane-1-carboxylate;benzyl (3S)-3-(3,5-difluorophenyl)-1-oxo-2-[2-oxo-2-[[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]amino]ethyl]-2,9-diazaspiro[5.5]undecane-9-carboxylate;2-[(5R,8S)-8-(3,5-difluorophenyl)-1-methyl-10-oxo-1,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide;2-[(5R,8S)-8-(3,5-difluorophenyl)-10-oxo-1-(2,2,2-trifluoroethyl)-1,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide
CID 158005847
benzyl 8-(3,5-difluorophenyl)-10-oxo-9-[2-oxo-2-[(2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl)amino]ethyl]-1,9-diazaspiro[4.5]decane-1-carboxylate;benzyl 3-(3,5-difluorophenyl)-1-oxo-2-[2-oxo-2-[(2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl)amino]ethyl]-2,9-diazaspiro[5.5]undecane-9-carboxylate;2-[8-(3,5-difluorophenyl)-1-methyl-10-oxo-1,9-diazaspiro[4.5]decan-9-yl]-N-(2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl)acetamide;2-[8-(3,5-difluorophenyl)-10-oxo-1-(2,2,2-trifluoroethyl)-1,9-diazaspiro[4.5]decan-9-yl]-N-(2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl)acetamide
CID 158005848
2-[4-[9,9-Dihexyl-7-[4-(5-methyl-[1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]fluoren-2-yl]phenyl]-5-methyl-[1,3]oxazolo[4,5-b]pyridine;2-[5-[9,9-dimethyl-7-[2-methyl-6-(5-methyl-[1,3]oxazolo[4,5-b]pyridin-2-yl)-3-pyridinyl]fluoren-2-yl]-6-methyl-2-pyridinyl]-5-methyl-[1,3]oxazolo[4,5-b]pyridine;2-[4-[9,9-dimethyl-7-[4-(5-methyl-[1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]fluoren-2-yl]phenyl]-5-methyl-[1,3]oxazolo[4,5-b]pyridine;2-[4-[9,9-dimethyl-7-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]fluoren-2-yl]phenyl]-[1,3]oxazolo[4,5-b]pyridine;5-methyl-2-[6-methyl-5-[7-[2-methyl-6-(5-methyl-[1,3]oxazolo[4,5-b]pyridin-2-yl)-3-pyridinyl]-9,9-bis(trifluoromethyl)fluoren-2-yl]-2-pyridinyl]-[1,3]oxazolo[4,5-b]pyridine
CID 158312442
2-[3-[9,9-Dihexyl-7-[3-(5-methyl-[1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]fluoren-2-yl]phenyl]-5-methyl-[1,3]oxazolo[4,5-b]pyridine;2-[3-[9,9-dimethyl-7-[3-(5-methyl-[1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]fluoren-2-yl]phenyl]-5-methyl-[1,3]oxazolo[4,5-b]pyridine;2-[6-[9,9-dimethyl-7-[6-(5-methyl-[1,3]oxazolo[4,5-b]pyridin-2-yl)-2-pyridinyl]fluoren-2-yl]-2-pyridinyl]-5-methyl-[1,3]oxazolo[4,5-b]pyridine;2-[3-[9,9-dimethyl-7-[3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]fluoren-2-yl]phenyl]-[1,3]oxazolo[4,5-b]pyridine;5-methyl-2-[6-[7-[6-(5-methyl-[1,3]oxazolo[4,5-b]pyridin-2-yl)-2-pyridinyl]-9,9-bis(trifluoromethyl)fluoren-2-yl]-2-pyridinyl]-[1,3]oxazolo[4,5-b]pyridine
CID 159148825
8-[4-(3-Fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
CID 159308601
8-[4-(3-Fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methylphenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
CID 159421169
CID 160962661
CID 160962661
(5S)-5-[5-(6-amino-3-pyridinyl)-6-fluorofuro[3,2-b]pyridin-2-yl]-5-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione;(3R)-3-[5-[4-(dimethylamino)piperidin-1-yl]furo[3,2-b]pyridin-2-yl]-3-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]pyrrolidine-2,5-dione;(5S)-5-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-(8-fluoro-7-oxo-5,6-dihydrocyclopenta[f][1]benzofuran-2-yl)imidazolidine-2,4-dione;(5S)-5-[(4-fluoro-5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]-5-[6-fluoro-5-(1,2,3,6-tetrahydropyridin-4-yl)furo[3,2-b]pyridin-2-yl]imidazolidine-2,4-dione
CID 157137041

Frequently Asked Questions

What is the IUPAC name of (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one?
The IUPAC name of (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one (CID 157373192) is (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one.
What is the SMILES notation for (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one?
The canonical SMILES for (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one is CC1(C)CC[C@@](C)(c2cc(F)cc(F)c2)N(C/C=C/c2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C1=O.CC1(C)CC[C@@](C)(c2cc(F)cc(F)c2)N(CCCc2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C1=O.CC1(C)NC[C@@](C)(c2cc(F)cc(F)c2)N(CCOc2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C1=O.CN1C[C@@](C)(c2cc(F)cc(F)c2)N(CCOc2ccc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C(=O)C12CCCC2.C[C@@]1(c2cc(F)cc(F)c2)CNC2(CCCC2)C(=O)N1CCOc1ccc2c(c1)C[C@@]1(C2)C(=O)Nc2ncccc21.
What is the InChIKey of (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one?
The InChIKey is BJZVSWVWZAUXPH-GXUJBRKLSA-N. The full InChI is InChI=1S/C33H34F2N4O3.C32H32F2N4O3.C32H33F2N3O2.C32H31F2N3O2.C30H30F2N4O3/c1-31(23-15-24(34)17-25(35)16-23)20-38(2)33(9-3-4-10-33)30(41)39(31)12-13-42-26-8-7-21-18-32(19-22(21)14-26)27-6-5-11-36-28(27)37-29(32)40;1-30(22-14-23(33)16-24(34)15-22)19-36-32(8-2-3-9-32)29(40)38(30)11-12-41-25-7-6-20-17-31(18-21(20)13-25)26-5-4-10-35-27(26)37-28(31)39;2*1-30(2)10-11-31(3,23-15-24(33)17-25(34)16-23)37(29(30)39)13-5-6-20-8-9-21-18-32(19-22(21)14-20)26-7-4-12-35-27(26)36-28(32)38;1-28(2)27(38)36(29(3,17-34-28)20-12-21(31)14-22(32)13-20)9-10-39-23-7-6-18-15-30(16-19(18)11-23)24-5-4-8-33-25(24)35-26(30)37/h5-8,11,14-17H,3-4,9-10,12-13,18-20H2,1-2H3,(H,36,37,40);4-7,10,13-16,36H,2-3,8-9,11-12,17-19H2,1H3,(H,35,37,39);4,7-9,12,14-17H,5-6,10-11,13,18-19H2,1-3H3,(H,35,36,38);4-9,12,14-17H,10-11,13,18-19H2,1-3H3,(H,35,36,38);4-8,11-14,34H,9-10,15-17H2,1-3H3,(H,33,35,37)/b;;;6-5+;/t31-,32+;30-,31+;2*31-,32+;29-,30+/m00000/s1.
What are the key properties of (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one?
(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one has a molecular weight of 2721.12 g/mol, XLogP of 24.74, 24 rotatable bonds, 7 hydrogen bond donors, and 21 hydrogen bond acceptors.
Where does this data come from?
All data for (2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]ethoxy]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[(E)-3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one;(2R)-5-[3-[(2S)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperidin-1-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one is sourced from PubChem (CID 157373192), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).