8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione

C114H108F9N21O18 — CID 159308601

About 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione

8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione (PubChem CID 159308601) has the molecular formula C114H108F9N21O18 and a molecular weight of 2231.23 g/mol. Its IUPAC name is 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione.

Molecular Properties

• Compound Name: 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
• PubChem CID: 159308601
• Molecular Formula: C114H108F9N21O18
• Molecular Weight: 2231.23 g/mol
• Exact Mass: 2229.80
• IUPAC Name: 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
• SMILES: COc1ccc(-c2ccnc(N3CCC4(CC3)NC(=O)NC4=O)c2)cc1.O=C1NC(=O)C2(CCN(c3ccc(Oc4ccc(F)cc4)cc3)CC2)N1.O=C1NC(=O)C2(CCN(c3ccc(Oc4ccc(F)cc4)cn3)CC2)N1.O=C1NC(=O)C2(CCN(c3ccc(Oc4cccc(C(F)(F)F)c4)cc3)CC2)N1.O=C1NC(=O)C2(CCN(c3ccc(Oc4cccc(C(F)(F)F)c4)cn3)CC2)N1.O=C1NC(=O)C2(CCN(c3ccc(Oc4cccc(F)c4)cc3)CC2)N1
• InChI: InChI=1S/C20H18F3N3O3.C19H17F3N4O3.2C19H18FN3O3.C19H20N4O3.C18H17FN4O3/c21-20(22,23)13-2-1-3-16(12-13)29-15-6-4-14(5-7-15)26-10-8-19(9-11-26)17(27)24-18(28)25-19;20-19(21,22)12-2-1-3-13(10-12)29-14-4-5-15(23-11-14)26-8-6-18(7-9-26)16(27)24-17(28)25-18;20-13-1-5-15(6-2-13)26-16-7-3-14(4-8-16)23-11-9-19(10-12-23)17(24)21-18(25)22-19;20-13-2-1-3-16(12-13)26-15-6-4-14(5-7-15)23-10-8-19(9-11-23)17(24)21-18(25)22-19;1-26-15-4-2-13(3-5-15)14-6-9-20-16(12-14)23-10-7-19(8-11-23)17(24)21-18(25)22-19;19-12-1-3-13(4-2-12)26-14-5-6-15(20-11-14)23-9-7-18(8-10-23)16(24)21-17(25)22-18/h1-7,12H,8-11H2,(H2,24,25,27,28);1-5,10-11H,6-9H2,(H2,24,25,27,28);1-8H,9-12H2,(H2,21,22,24,25);1-7,12H,8-11H2,(H2,21,22,24,25);2-6,9,12H,7-8,10-11H2,1H3,(H2,21,22,24,25);1-6,11H,7-10H2,(H2,21,22,24,25)
• InChIKey: LCFXGQRGMOJZKZ-UHFFFAOYSA-N
• XLogP: 16.47
• TPSA: 462.69 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 27
• Rotatable Bonds: 18
• Heavy Atoms: 162
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2231.23
LogP ≤ 5	16.47
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	27

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione?

The IUPAC name of 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione (CID 159308601) is 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione.

What is the SMILES notation for 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione?

The canonical SMILES for 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione is COc1ccc(-c2ccnc(N3CCC4(CC3)NC(=O)NC4=O)c2)cc1.O=C1NC(=O)C2(CCN(c3ccc(Oc4ccc(F)cc4)cc3)CC2)N1.O=C1NC(=O)C2(CCN(c3ccc(Oc4ccc(F)cc4)cn3)CC2)N1.O=C1NC(=O)C2(CCN(c3ccc(Oc4cccc(C(F)(F)F)c4)cc3)CC2)N1.O=C1NC(=O)C2(CCN(c3ccc(Oc4cccc(C(F)(F)F)c4)cn3)CC2)N1.O=C1NC(=O)C2(CCN(c3ccc(Oc4cccc(F)c4)cc3)CC2)N1.

What is the InChIKey of 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione?

The InChIKey is LCFXGQRGMOJZKZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H18F3N3O3.C19H17F3N4O3.2C19H18FN3O3.C19H20N4O3.C18H17FN4O3/c21-20(22,23)13-2-1-3-16(12-13)29-15-6-4-14(5-7-15)26-10-8-19(9-11-26)17(27)24-18(28)25-19;20-19(21,22)12-2-1-3-13(10-12)29-14-4-5-15(23-11-14)26-8-6-18(7-9-26)16(27)24-17(28)25-18;20-13-1-5-15(6-2-13)26-16-7-3-14(4-8-16)23-11-9-19(10-12-23)17(24)21-18(25)22-19;20-13-2-1-3-16(12-13)26-15-6-4-14(5-7-15)23-10-8-19(9-11-23)17(24)21-18(25)22-19;1-26-15-4-2-13(3-5-15)14-6-9-20-16(12-14)23-10-7-19(8-11-23)17(24)21-18(25)22-19;19-12-1-3-13(4-2-12)26-14-5-6-15(20-11-14)23-9-7-18(8-10-23)16(24)21-17(25)22-18/h1-7,12H,8-11H2,(H2,24,25,27,28);1-5,10-11H,6-9H2,(H2,24,25,27,28);1-8H,9-12H2,(H2,21,22,24,25);1-7,12H,8-11H2,(H2,21,22,24,25);2-6,9,12H,7-8,10-11H2,1H3,(H2,21,22,24,25);1-6,11H,7-10H2,(H2,21,22,24,25).

What are the key properties of 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione?

8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione has a molecular weight of 2231.23 g/mol, XLogP of 16.47, 18 rotatable bonds, 12 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for 8-[4-(3-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-fluorophenoxy)phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-(4-fluorophenoxy)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-(4-methoxyphenyl)-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[4-[3-(trifluoromethyl)phenoxy]phenyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;8-[5-[3-(trifluoromethyl)phenoxy]-2-pyridinyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione is sourced from PubChem (CID 159308601), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).