5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide

C156H137Cl2F17N18O16 — CID 157439912

IUPAC5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
SMILESCNC(=O)c1c(-c2ccc(C)cc2)oc2nc(CCC(F)(F)F)c(-c3cc(Cl)c(Cl)c(C(=O)CC(C)(C)C#N)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(CCC(F)(F)F)c(-c3cc(F)c(F)c(C(=O)CC(C)(C#N)C4CC4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cccc(C(=O)CC(C)(C)C#N)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cccc(C(=O)CC(C)C#N)c3)cc12.[2H]C([2H])([2H])Oc1ncc(-c2cc3c(C(=O)NC)c(-c4ccc(C)cc4)oc3nc2CCC(F)(F)F)cc1C(=O)CC(C)(C#N)C1CC1
InChIInChI=1S/C33H28F5N3O3.C33H31F3N4O4.C31H26Cl2F3N3O3.C30H27F3N4O3.C29H25F3N4O3/c1-17-4-6-18(7-5-17)29-27(30(43)40-3)23-14-21(25(41-31(23)44-29)10-11-33(36,37)38)19-12-22(28(35)24(34)13-19)26(42)15-32(2,16-39)20-8-9-20;1-18-5-7-19(8-6-18)28-27(29(42)38-3)24-14-22(25(40-31(24)44-28)11-12-33(34,35)36)20-13-23(30(43-4)39-16-20)26(41)15-32(2,17-37)21-9-10-21;1-16-5-7-17(8-6-16)27-25(28(41)38-4)21-13-19(23(39-29(21)42-27)9-10-31(34,35)36)18-11-20(26(33)22(32)12-18)24(40)14-30(2,3)15-37;1-17-8-10-18(11-9-17)25-24(27(39)35-4)22-13-21(26(37-28(22)40-25)36-16-30(31,32)33)19-6-5-7-20(12-19)23(38)14-29(2,3)15-34;1-16-7-9-18(10-8-16)25-24(27(38)34-3)22-13-21(26(36-28(22)39-25)35-15-29(30,31)32)19-5-4-6-20(12-19)23(37)11-17(2)14-33/h4-7,12-14,20H,8-11,15H2,1-3H3,(H,40,43);5-8,13-14,16,21H,9-12,15H2,1-4H3,(H,38,42);5-8,11-13H,9-10,14H2,1-4H3,(H,38,41);5-13H,14,16H2,1-4H3,(H,35,39)(H,36,37);4-10,12-13,17H,11,15H2,1-3H3,(H,34,38)(H,35,36)/i;4D3;;;
InChIKeyBRNVOUQDRLOYQG-FGSUNDNBSA-N
MW2916.81 g/mol
LogP37.57
Rot. Bonds44

About 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide

5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide (PubChem CID 157439912) has the molecular formula C156H137Cl2F17N18O16 and a molecular weight of 2916.81 g/mol. Its IUPAC name is 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide.

Molecular Properties

Compound Name5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
PubChem CID157439912
Molecular FormulaC156H137Cl2F17N18O16
Molecular Weight2916.81 g/mol
Exact Mass2913.98
IUPAC Name5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
SMILESCNC(=O)c1c(-c2ccc(C)cc2)oc2nc(CCC(F)(F)F)c(-c3cc(Cl)c(Cl)c(C(=O)CC(C)(C)C#N)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(CCC(F)(F)F)c(-c3cc(F)c(F)c(C(=O)CC(C)(C#N)C4CC4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cccc(C(=O)CC(C)(C)C#N)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cccc(C(=O)CC(C)C#N)c3)cc12.[2H]C([2H])([2H])Oc1ncc(-c2cc3c(C(=O)NC)c(-c4ccc(C)cc4)oc3nc2CCC(F)(F)F)cc1C(=O)CC(C)(C#N)C1CC1
InChIInChI=1S/C33H28F5N3O3.C33H31F3N4O4.C31H26Cl2F3N3O3.C30H27F3N4O3.C29H25F3N4O3/c1-17-4-6-18(7-5-17)29-27(30(43)40-3)23-14-21(25(41-31(23)44-29)10-11-33(36,37)38)19-12-22(28(35)24(34)13-19)26(42)15-32(2,16-39)20-8-9-20;1-18-5-7-19(8-6-18)28-27(29(42)38-3)24-14-22(25(40-31(24)44-28)11-12-33(34,35)36)20-13-23(30(43-4)39-16-20)26(41)15-32(2,17-37)21-9-10-21;1-16-5-7-17(8-6-16)27-25(28(41)38-4)21-13-19(23(39-29(21)42-27)9-10-31(34,35)36)18-11-20(26(33)22(32)12-18)24(40)14-30(2,3)15-37;1-17-8-10-18(11-9-17)25-24(27(39)35-4)22-13-21(26(37-28(22)40-25)36-16-30(31,32)33)19-6-5-7-20(12-19)23(38)14-29(2,3)15-34;1-16-7-9-18(10-8-16)25-24(27(38)34-3)22-13-21(26(36-28(22)39-25)35-15-29(30,31)32)19-5-4-6-20(12-19)23(37)11-17(2)14-33/h4-7,12-14,20H,8-11,15H2,1-3H3,(H,40,43);5-8,13-14,16,21H,9-12,15H2,1-4H3,(H,38,42);5-8,11-13H,9-10,14H2,1-4H3,(H,38,41);5-13H,14,16H2,1-4H3,(H,35,39)(H,36,37);4-10,12-13,17H,11,15H2,1-3H3,(H,34,38)(H,35,36)/i;4D3;;;
InChIKeyBRNVOUQDRLOYQG-FGSUNDNBSA-N
XLogP37.57
TPSA526.13 Ų
H-Bond Donors7
H-Bond Acceptors29
Rotatable Bonds44
Heavy Atoms209
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002916.81
LogP ≤ 537.57
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1029

Analyze 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide with MolForge

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Related Compounds

5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(2-cyano-3-methylbutan-2-yl)carbamoyl]phenyl]-2-(4-fluorophenyl)-N-methyl-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide
CID 157082910
5-[3-[(1-cyanocyclobutyl)carbamoyl]-4-fluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(1-cyanocyclopropyl)carbamoyl]-4-fluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-6-ethenyl-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;bis(5-[3-(3-cyano-3-methylbutanoyl)phenyl]-6-(2-hydroxyethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide)
CID 157099452
5-[3-[(1-cyanocyclopentyl)carbamoyl]-4-fluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(1-cyanocyclopentyl)carbamoyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(1-cyanocyclopropyl)carbamoyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-4-fluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide
CID 157469943
5-[3-[(1-cyanocyclobutyl)carbamoyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(1-cyanocyclopentyl)carbamoyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(1-cyanocyclopropyl)carbamoyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(1-cyanocyclopropyl)carbamoyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(2-cyano-3-methylbutan-2-yl)carbamoyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide
CID 157610900
5-[5-[(1-cyanocyclobutyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(2-cyanopropan-2-ylcarbamoyl)-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide
CID 157613435
tris(5-[3-(3-cyanobutanoyl)-4-fluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide);bis(5-[3-(3-cyano-3-cyclopropylbutanoyl)-4-fluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide);5-[3-(3-cyano-3-methylbutanoyl)-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide
CID 157940671
5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-methylbutanoyl)-2-fluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
CID 158058758
5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(1-cyanocyclopropyl)carbamoyl]-4-fluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-methylbutanoyl)-2-fluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide
CID 158090986
5-[3-[2-(1-cyanocyclopentyl)acetyl]phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,3,3,3-pentafluoropropylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,3,3,3-pentafluoropropylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(1-cyanocyclopropyl)carbamoyl]-4-fluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3,4-dimethylpentanoyl)-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,3,3,3-pentafluoropropylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-6-ethenyl-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-6-(2-hydroxyethylamino)-N-methyl-2-(4-methylphenyl)furo[2,3-b]pyridine-3-carboxamide
CID 158296475
5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide
CID 158409256
5-[3-[(1-cyanocyclopentyl)carbamoyl]-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(1-cyanocyclopropyl)carbamoyl]-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(1-cyanocyclopropyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-4-methoxyphenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide
CID 158467931
5-[5-[(1-cyanocyclobutyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(1-cyanocyclopropyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(2-cyanopropan-2-ylcarbamoyl)-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide
CID 158931094

Frequently Asked Questions

What is the IUPAC name of 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide?
The IUPAC name of 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide (CID 157439912) is 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide.
What is the SMILES notation for 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide?
The canonical SMILES for 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide is CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(CCC(F)(F)F)c(-c3cc(Cl)c(Cl)c(C(=O)CC(C)(C)C#N)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(CCC(F)(F)F)c(-c3cc(F)c(F)c(C(=O)CC(C)(C#N)C4CC4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cccc(C(=O)CC(C)(C)C#N)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cccc(C(=O)CC(C)C#N)c3)cc12.[2H]C([2H])([2H])Oc1ncc(-c2cc3c(C(=O)NC)c(-c4ccc(C)cc4)oc3nc2CCC(F)(F)F)cc1C(=O)CC(C)(C#N)C1CC1.
What is the InChIKey of 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide?
The InChIKey is BRNVOUQDRLOYQG-FGSUNDNBSA-N. The full InChI is InChI=1S/C33H28F5N3O3.C33H31F3N4O4.C31H26Cl2F3N3O3.C30H27F3N4O3.C29H25F3N4O3/c1-17-4-6-18(7-5-17)29-27(30(43)40-3)23-14-21(25(41-31(23)44-29)10-11-33(36,37)38)19-12-22(28(35)24(34)13-19)26(42)15-32(2,16-39)20-8-9-20;1-18-5-7-19(8-6-18)28-27(29(42)38-3)24-14-22(25(40-31(24)44-28)11-12-33(34,35)36)20-13-23(30(43-4)39-16-20)26(41)15-32(2,17-37)21-9-10-21;1-16-5-7-17(8-6-16)27-25(28(41)38-4)21-13-19(23(39-29(21)42-27)9-10-31(34,35)36)18-11-20(26(33)22(32)12-18)24(40)14-30(2,3)15-37;1-17-8-10-18(11-9-17)25-24(27(39)35-4)22-13-21(26(37-28(22)40-25)36-16-30(31,32)33)19-6-5-7-20(12-19)23(38)14-29(2,3)15-34;1-16-7-9-18(10-8-16)25-24(27(38)34-3)22-13-21(26(36-28(22)39-25)35-15-29(30,31)32)19-5-4-6-20(12-19)23(37)11-17(2)14-33/h4-7,12-14,20H,8-11,15H2,1-3H3,(H,40,43);5-8,13-14,16,21H,9-12,15H2,1-4H3,(H,38,42);5-8,11-13H,9-10,14H2,1-4H3,(H,38,41);5-13H,14,16H2,1-4H3,(H,35,39)(H,36,37);4-10,12-13,17H,11,15H2,1-3H3,(H,34,38)(H,35,36)/i;4D3;;;.
What are the key properties of 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide?
5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide has a molecular weight of 2916.81 g/mol, XLogP of 37.57, 44 rotatable bonds, 7 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[3-(3-cyanobutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-cyclopropylbutanoyl)-4,5-difluorophenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[5-(3-cyano-3-cyclopropylbutanoyl)-6-(trideuteriomethoxy)-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[3-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3,4-dichloro-5-(3-cyano-3-methylbutanoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide is sourced from PubChem (CID 157439912), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).