5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide

C121H115F9N20O15 — CID 158409256

About 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide

5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide (PubChem CID 158409256) has the molecular formula C121H115F9N20O15 and a molecular weight of 2260.36 g/mol. Its IUPAC name is 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide
• PubChem CID: 158409256
• Molecular Formula: C121H115F9N20O15
• Molecular Weight: 2260.36 g/mol
• Exact Mass: 2258.87
• IUPAC Name: 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide
• SMILES: CCCc1nc2oc(-c3ccc(C)cc3)c(C(=O)NC)c2cc1-c1cccc(C(=O)NC(C)(C)C#N)c1.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cnc(OC)c(C(=O)NC(C)(C#N)C(C)C)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cnc(OC)c(C(=O)NC4(C#N)CCCC4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(OCC(F)(F)F)c(-c3cccc(C(=O)NC(C)(C)C#N)c3)cc12
• InChI: InChI=1S/C31H29F3N6O4.C31H31F3N6O4.C30H30N4O3.C29H25F3N4O4/c1-17-6-8-18(9-7-17)24-23(27(42)36-2)21-13-20(25(39-29(21)44-24)38-16-31(32,33)34)19-12-22(28(43-3)37-14-19)26(41)40-30(15-35)10-4-5-11-30;1-16(2)30(4,14-35)40-26(41)22-11-19(13-37-28(22)43-6)20-12-21-23(27(42)36-5)24(18-9-7-17(3)8-10-18)44-29(21)39-25(20)38-15-31(32,33)34;1-6-8-24-22(20-9-7-10-21(15-20)27(35)34-30(3,4)17-31)16-23-25(28(36)32-5)26(37-29(23)33-24)19-13-11-18(2)12-14-19;1-16-8-10-17(11-9-16)23-22(25(38)34-4)21-13-20(26(35-27(21)40-23)39-15-29(30,31)32)18-6-5-7-19(12-18)24(37)36-28(2,3)14-33/h6-9,12-14H,4-5,10-11,16H2,1-3H3,(H,36,42)(H,38,39)(H,40,41);7-13,16H,15H2,1-6H3,(H,36,42)(H,38,39)(H,40,41);7,9-16H,6,8H2,1-5H3,(H,32,36)(H,34,35);5-13H,15H2,1-4H3,(H,34,38)(H,36,37)
• InChIKey: GZCAMGLJOKRYLV-UHFFFAOYSA-N
• XLogP: 23.27
• TPSA: 509.61 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 27
• Rotatable Bonds: 31
• Heavy Atoms: 165
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2260.36
LogP ≤ 5	23.27
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	27

Frequently Asked Questions

What is the IUPAC name of 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide?

The IUPAC name of 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide (CID 158409256) is 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide.

What is the SMILES notation for 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide?

The canonical SMILES for 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide is CCCc1nc2oc(-c3ccc(C)cc3)c(C(=O)NC)c2cc1-c1cccc(C(=O)NC(C)(C)C#N)c1.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cnc(OC)c(C(=O)NC(C)(C#N)C(C)C)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cnc(OC)c(C(=O)NC4(C#N)CCCC4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(OCC(F)(F)F)c(-c3cccc(C(=O)NC(C)(C)C#N)c3)cc12.

What is the InChIKey of 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide?

The InChIKey is GZCAMGLJOKRYLV-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H29F3N6O4.C31H31F3N6O4.C30H30N4O3.C29H25F3N4O4/c1-17-6-8-18(9-7-17)24-23(27(42)36-2)21-13-20(25(39-29(21)44-24)38-16-31(32,33)34)19-12-22(28(43-3)37-14-19)26(41)40-30(15-35)10-4-5-11-30;1-16(2)30(4,14-35)40-26(41)22-11-19(13-37-28(22)43-6)20-12-21-23(27(42)36-5)24(18-9-7-17(3)8-10-18)44-29(21)39-25(20)38-15-31(32,33)34;1-6-8-24-22(20-9-7-10-21(15-20)27(35)34-30(3,4)17-31)16-23-25(28(36)32-5)26(37-29(23)33-24)19-13-11-18(2)12-14-19;1-16-8-10-17(11-9-16)23-22(25(38)34-4)21-13-20(26(35-27(21)40-23)39-15-29(30,31)32)18-6-5-7-19(12-18)24(37)36-28(2,3)14-33/h6-9,12-14H,4-5,10-11,16H2,1-3H3,(H,36,42)(H,38,39)(H,40,41);7-13,16H,15H2,1-6H3,(H,36,42)(H,38,39)(H,40,41);7,9-16H,6,8H2,1-5H3,(H,32,36)(H,34,35);5-13H,15H2,1-4H3,(H,34,38)(H,36,37).

What are the key properties of 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide?

5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide has a molecular weight of 2260.36 g/mol, XLogP of 23.27, 31 rotatable bonds, 10 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[5-[(1-cyanocyclopentyl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[5-[(2-cyano-3-methylbutan-2-yl)carbamoyl]-6-methoxy-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-propylfuro[2,3-b]pyridine-3-carboxamide;5-[3-(2-cyanopropan-2-ylcarbamoyl)phenyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethoxy)furo[2,3-b]pyridine-3-carboxamide is sourced from PubChem (CID 158409256), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).