tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile

C264H274N82O13 — CID 157459253

IUPACtert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile
SMILESCC(C)CC(=O)N1CCN(c2ccc(-c3cc(-c4ccn(C)n4)cn4ncc(C#N)c34)cn2)CC1.CO[C@H]1CCN(C(=O)N2CCN(c3ccc(-c4cc(-c5ccn(C)n5)cn5ncc(C#N)c45)cn3)CC2)C1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)CC(C)(C)C)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)CC(C)(C)O)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)N2CCCC2)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)OC(C)(C)C)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)[C@H](O)c2ccccc2)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCNCC1.Cn1ccc(-c2cc(-c3ccc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)nc3)c3c(C#N)cnn3c2)n1.Cn1ccc(-c2cc(-c3ccc(N4CCNCC4)nc3)c3c(C#N)cnn3c2)n1
InChIInChI=1S/C30H28N8O2.C29H26N8O2.C28H32N8O.C27H29N9O2.C27H29N9O.2C27H30N8O2.C26H28N8O.C22H22N8.C21H20N8/c1-20-12-22(26-13-23(25-17-33-35(2)18-25)19-38-27(26)24(14-31)16-34-38)15-32-29(20)36-8-10-37(11-9-36)30(40)28(39)21-6-4-3-5-7-21;1-34-10-9-25(33-34)22-15-24(27-23(16-30)18-32-37(27)19-22)21-7-8-26(31-17-21)35-11-13-36(14-12-35)29(39)28(38)20-5-3-2-4-6-20;1-19-10-20(14-30-27(19)35-8-6-34(7-9-35)25(37)12-28(2,3)4)24-11-21(23-16-31-33(5)17-23)18-36-26(24)22(13-29)15-32-36;1-32-7-6-24(31-32)20-13-23(26-21(14-28)16-30-36(26)17-20)19-3-4-25(29-15-19)33-9-11-34(12-10-33)27(37)35-8-5-22(18-35)38-2;1-19-11-20(14-29-26(19)33-7-9-35(10-8-33)27(37)34-5-3-4-6-34)24-12-21(23-16-30-32(2)17-23)18-36-25(24)22(13-28)15-31-36;1-18-10-19(13-29-25(18)33-6-8-34(9-7-33)26(36)37-27(2,3)4)23-11-20(22-15-30-32(5)16-22)17-35-24(23)21(12-28)14-31-35;1-18-9-19(13-29-26(18)34-7-5-33(6-8-34)24(36)11-27(2,3)37)23-10-20(22-15-30-32(4)16-22)17-35-25(23)21(12-28)14-31-35;1-18(2)12-25(35)33-10-8-32(9-11-33)24-5-4-19(15-28-24)22-13-20(23-6-7-31(3)30-23)17-34-26(22)21(14-27)16-29-34;1-15-7-16(10-25-22(15)29-5-3-24-4-6-29)20-8-17(19-12-26-28(2)13-19)14-30-21(20)18(9-23)11-27-30;1-27-7-4-19(26-27)16-10-18(21-17(11-22)13-25-29(21)14-16)15-2-3-20(24-12-15)28-8-5-23-6-9-28/h3-7,12-13,15-19,28,39H,8-11H2,1-2H3;2-10,15,17-19,28,38H,11-14H2,1H3;10-11,14-18H,6-9,12H2,1-5H3;3-4,6-7,13,15-17,22H,5,8-12,18H2,1-2H3;11-12,14-18H,3-10H2,1-2H3;10-11,13-17H,6-9H2,1-5H3;9-10,13-17,37H,5-8,11H2,1-4H3;4-7,13,15-18H,8-12H2,1-3H3;7-8,10-14,24H,3-6H2,1-2H3;2-4,7,10,12-14,23H,5-6,8-9H2,1H3/t2*28-;;22-;;;;;;/m11.0....../s1
InChIKeyBTSPSQZBUVHECO-AIWPGYTCSA-N
MW4803.66 g/mol
LogP31.07
Rot. Bonds40

About tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile

tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile (PubChem CID 157459253) has the molecular formula C264H274N82O13 and a molecular weight of 4803.66 g/mol. Its IUPAC name is tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile.

Molecular Properties

Compound Nametert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile
PubChem CID157459253
Molecular FormulaC264H274N82O13
Molecular Weight4803.66 g/mol
Exact Mass4800.33
IUPAC Nametert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile
SMILESCC(C)CC(=O)N1CCN(c2ccc(-c3cc(-c4ccn(C)n4)cn4ncc(C#N)c34)cn2)CC1.CO[C@H]1CCN(C(=O)N2CCN(c3ccc(-c4cc(-c5ccn(C)n5)cn5ncc(C#N)c45)cn3)CC2)C1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)CC(C)(C)C)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)CC(C)(C)O)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)N2CCCC2)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)OC(C)(C)C)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)[C@H](O)c2ccccc2)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCNCC1.Cn1ccc(-c2cc(-c3ccc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)nc3)c3c(C#N)cnn3c2)n1.Cn1ccc(-c2cc(-c3ccc(N4CCNCC4)nc3)c3c(C#N)cnn3c2)n1
InChIInChI=1S/C30H28N8O2.C29H26N8O2.C28H32N8O.C27H29N9O2.C27H29N9O.2C27H30N8O2.C26H28N8O.C22H22N8.C21H20N8/c1-20-12-22(26-13-23(25-17-33-35(2)18-25)19-38-27(26)24(14-31)16-34-38)15-32-29(20)36-8-10-37(11-9-36)30(40)28(39)21-6-4-3-5-7-21;1-34-10-9-25(33-34)22-15-24(27-23(16-30)18-32-37(27)19-22)21-7-8-26(31-17-21)35-11-13-36(14-12-35)29(39)28(38)20-5-3-2-4-6-20;1-19-10-20(14-30-27(19)35-8-6-34(7-9-35)25(37)12-28(2,3)4)24-11-21(23-16-31-33(5)17-23)18-36-26(24)22(13-29)15-32-36;1-32-7-6-24(31-32)20-13-23(26-21(14-28)16-30-36(26)17-20)19-3-4-25(29-15-19)33-9-11-34(12-10-33)27(37)35-8-5-22(18-35)38-2;1-19-11-20(14-29-26(19)33-7-9-35(10-8-33)27(37)34-5-3-4-6-34)24-12-21(23-16-30-32(2)17-23)18-36-25(24)22(13-28)15-31-36;1-18-10-19(13-29-25(18)33-6-8-34(9-7-33)26(36)37-27(2,3)4)23-11-20(22-15-30-32(5)16-22)17-35-24(23)21(12-28)14-31-35;1-18-9-19(13-29-26(18)34-7-5-33(6-8-34)24(36)11-27(2,3)37)23-10-20(22-15-30-32(4)16-22)17-35-25(23)21(12-28)14-31-35;1-18(2)12-25(35)33-10-8-32(9-11-33)24-5-4-19(15-28-24)22-13-20(23-6-7-31(3)30-23)17-34-26(22)21(14-27)16-29-34;1-15-7-16(10-25-22(15)29-5-3-24-4-6-29)20-8-17(19-12-26-28(2)13-19)14-30-21(20)18(9-23)11-27-30;1-27-7-4-19(26-27)16-10-18(21-17(11-22)13-25-29(21)14-16)15-2-3-20(24-12-15)28-8-5-23-6-9-28/h3-7,12-13,15-19,28,39H,8-11H2,1-2H3;2-10,15,17-19,28,38H,11-14H2,1H3;10-11,14-18H,6-9,12H2,1-5H3;3-4,6-7,13,15-17,22H,5,8-12,18H2,1-2H3;11-12,14-18H,3-10H2,1-2H3;10-11,13-17H,6-9H2,1-5H3;9-10,13-17,37H,5-8,11H2,1-4H3;4-7,13,15-18H,8-12H2,1-3H3;7-8,10-14,24H,3-6H2,1-2H3;2-4,7,10,12-14,23H,5-6,8-9H2,1H3/t2*28-;;22-;;;;;;/m11.0....../s1
InChIKeyBTSPSQZBUVHECO-AIWPGYTCSA-N
XLogP31.07
TPSA1022.57 Ų
H-Bond Donors5
H-Bond Acceptors85
Rotatable Bonds40
Heavy Atoms359
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5004803.66
LogP ≤ 531.07
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1085

Analyze tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile with MolForge

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Related Compounds

US10023570, Example 82
CID 124199946
US10023570, Example 272
CID 124200126
US10023570, Example 6
CID 126740487
CID 158598881
CID 158598881
CID 159080356
CID 159080356
CID 159802198
CID 159802198
CID 161943841
CID 161943841
4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;hydrochloride
CID 135150192
4-[6-[4-(2-Hydroxy-2-phenylacetyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;hydrochloride
CID 135150193
4-[6-[4-(2-Hydroxy-2-phenylacetyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
CID 135150194
2-amino-4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
CID 146528469
4-[6-[4-(2-Hydroxy-2-phenylacetyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
CID 155267143

Frequently Asked Questions

What is the IUPAC name of tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
The IUPAC name of tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile (CID 157459253) is tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile.
What is the SMILES notation for tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
The canonical SMILES for tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile is CC(C)CC(=O)N1CCN(c2ccc(-c3cc(-c4ccn(C)n4)cn4ncc(C#N)c34)cn2)CC1.CO[C@H]1CCN(C(=O)N2CCN(c3ccc(-c4cc(-c5ccn(C)n5)cn5ncc(C#N)c45)cn3)CC2)C1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)CC(C)(C)C)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)CC(C)(C)O)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)N2CCCC2)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)OC(C)(C)C)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCN(C(=O)[C@H](O)c2ccccc2)CC1.Cc1cc(-c2cc(-c3cnn(C)c3)cn3ncc(C#N)c23)cnc1N1CCNCC1.Cn1ccc(-c2cc(-c3ccc(N4CCN(C(=O)[C@H](O)c5ccccc5)CC4)nc3)c3c(C#N)cnn3c2)n1.Cn1ccc(-c2cc(-c3ccc(N4CCNCC4)nc3)c3c(C#N)cnn3c2)n1.
What is the InChIKey of tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
The InChIKey is BTSPSQZBUVHECO-AIWPGYTCSA-N. The full InChI is InChI=1S/C30H28N8O2.C29H26N8O2.C28H32N8O.C27H29N9O2.C27H29N9O.2C27H30N8O2.C26H28N8O.C22H22N8.C21H20N8/c1-20-12-22(26-13-23(25-17-33-35(2)18-25)19-38-27(26)24(14-31)16-34-38)15-32-29(20)36-8-10-37(11-9-36)30(40)28(39)21-6-4-3-5-7-21;1-34-10-9-25(33-34)22-15-24(27-23(16-30)18-32-37(27)19-22)21-7-8-26(31-17-21)35-11-13-36(14-12-35)29(39)28(38)20-5-3-2-4-6-20;1-19-10-20(14-30-27(19)35-8-6-34(7-9-35)25(37)12-28(2,3)4)24-11-21(23-16-31-33(5)17-23)18-36-26(24)22(13-29)15-32-36;1-32-7-6-24(31-32)20-13-23(26-21(14-28)16-30-36(26)17-20)19-3-4-25(29-15-19)33-9-11-34(12-10-33)27(37)35-8-5-22(18-35)38-2;1-19-11-20(14-29-26(19)33-7-9-35(10-8-33)27(37)34-5-3-4-6-34)24-12-21(23-16-30-32(2)17-23)18-36-25(24)22(13-28)15-31-36;1-18-10-19(13-29-25(18)33-6-8-34(9-7-33)26(36)37-27(2,3)4)23-11-20(22-15-30-32(5)16-22)17-35-24(23)21(12-28)14-31-35;1-18-9-19(13-29-26(18)34-7-5-33(6-8-34)24(36)11-27(2,3)37)23-10-20(22-15-30-32(4)16-22)17-35-25(23)21(12-28)14-31-35;1-18(2)12-25(35)33-10-8-32(9-11-33)24-5-4-19(15-28-24)22-13-20(23-6-7-31(3)30-23)17-34-26(22)21(14-27)16-29-34;1-15-7-16(10-25-22(15)29-5-3-24-4-6-29)20-8-17(19-12-26-28(2)13-19)14-30-21(20)18(9-23)11-27-30;1-27-7-4-19(26-27)16-10-18(21-17(11-22)13-25-29(21)14-16)15-2-3-20(24-12-15)28-8-5-23-6-9-28/h3-7,12-13,15-19,28,39H,8-11H2,1-2H3;2-10,15,17-19,28,38H,11-14H2,1H3;10-11,14-18H,6-9,12H2,1-5H3;3-4,6-7,13,15-17,22H,5,8-12,18H2,1-2H3;11-12,14-18H,3-10H2,1-2H3;10-11,13-17H,6-9H2,1-5H3;9-10,13-17,37H,5-8,11H2,1-4H3;4-7,13,15-18H,8-12H2,1-3H3;7-8,10-14,24H,3-6H2,1-2H3;2-4,7,10,12-14,23H,5-6,8-9H2,1H3/t2*28-;;22-;;;;;;/m11.0....../s1.
What are the key properties of tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile?
tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile has a molecular weight of 4803.66 g/mol, XLogP of 31.07, 40 rotatable bonds, 5 hydrogen bond donors, and 85 hydrogen bond acceptors.
Where does this data come from?
All data for tert-butyl 4-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-3-methyl-2-pyridinyl]piperazine-1-carboxylate;4-[6-[4-(3,3-dimethylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-hydroxy-3-methylbutanoyl)piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-5-methyl-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2R)-2-hydroxy-2-phenylacetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(3S)-3-methoxypyrrolidine-1-carbonyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-(3-methylbutanoyl)piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-(5-methyl-6-piperazin-1-yl-3-pyridinyl)-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-4-yl)-4-[5-methyl-6-[4-(pyrrolidine-1-carbonyl)piperazin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile;6-(1-methylpyrazol-3-yl)-4-(6-piperazin-1-yl-3-pyridinyl)pyrazolo[1,5-a]pyridine-3-carbonitrile is sourced from PubChem (CID 157459253), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).