cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide

C115H124F6N30O8 — CID 157459300

IUPACcis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
SMILESCC[C@@H]1CCCN1c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1.CC[C@H]1CCCN1c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1.CC[C@H]1CCCN1c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1.CCc1cc(OC)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1.CCc1cc(OC)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1.Cn1ccc2cccc(-c3cc4cc(NC(=O)[C@@H]5C[C@@H]5F)ncc4c(N)n3)c21
InChIInChI=1S/C21H18FN5O.2C20H20FN5O2.3C18H22FN5O/c1-27-6-5-11-3-2-4-13(19(11)27)17-7-12-8-18(24-10-15(12)20(23)25-17)26-21(28)14-9-16(14)22;2*1-3-10-6-18(28-2)24-8-13(10)16-4-11-5-17(23-9-14(11)19(22)25-16)26-20(27)12-7-15(12)21;3*1-2-11-4-3-5-24(11)16-7-10-6-15(21-9-13(10)17(20)23-16)22-18(25)12-8-14(12)19/h2-8,10,14,16H,9H2,1H3,(H2,23,25)(H,24,26,28);2*4-6,8-9,12,15H,3,7H2,1-2H3,(H2,22,25)(H,23,26,27);3*6-7,9,11-12,14H,2-5,8H2,1H3,(H2,20,23)(H,21,22,25)/t14-,16+;2*12-,15+;2*11-,12+,14-;11-,12-,14+/m110100/s1
InChIKeyBTSSUZYGQQTRNV-WUXASEMTSA-N
MW2168.45 g/mol
LogP18.61
Rot. Bonds25

About cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide

cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide (PubChem CID 157459300) has the molecular formula C115H124F6N30O8 and a molecular weight of 2168.45 g/mol. Its IUPAC name is cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide.

Molecular Properties

Compound Namecis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
PubChem CID157459300
Molecular FormulaC115H124F6N30O8
Molecular Weight2168.45 g/mol
Exact Mass2167.01
IUPAC Namecis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
SMILESCC[C@@H]1CCCN1c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1.CC[C@H]1CCCN1c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1.CC[C@H]1CCCN1c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1.CCc1cc(OC)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1.CCc1cc(OC)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1.Cn1ccc2cccc(-c3cc4cc(NC(=O)[C@@H]5C[C@@H]5F)ncc4c(N)n3)c21
InChIInChI=1S/C21H18FN5O.2C20H20FN5O2.3C18H22FN5O/c1-27-6-5-11-3-2-4-13(19(11)27)17-7-12-8-18(24-10-15(12)20(23)25-17)26-21(28)14-9-16(14)22;2*1-3-10-6-18(28-2)24-8-13(10)16-4-11-5-17(23-9-14(11)19(22)25-16)26-20(27)12-7-15(12)21;3*1-2-11-4-3-5-24(11)16-7-10-6-15(21-9-13(10)17(20)23-16)22-18(25)12-8-14(12)19/h2-8,10,14,16H,9H2,1H3,(H2,23,25)(H,24,26,28);2*4-6,8-9,12,15H,3,7H2,1-2H3,(H2,22,25)(H,23,26,27);3*6-7,9,11-12,14H,2-5,8H2,1H3,(H2,20,23)(H,21,22,25)/t14-,16+;2*12-,15+;2*11-,12+,14-;11-,12-,14+/m110100/s1
InChIKeyBTSSUZYGQQTRNV-WUXASEMTSA-N
XLogP18.61
TPSA544.29 Ų
H-Bond Donors12
H-Bond Acceptors32
Rotatable Bonds25
Heavy Atoms159
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002168.45
LogP ≤ 518.61
H-Bond Donors ≤ 512
H-Bond Acceptors ≤ 1032

Analyze cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide with MolForge

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Related Compounds

cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
CID 157062355
cis-(1S,2S)-N-[8-amino-6-[(2R)-2-propylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
CID 142447473
N-[8-amino-6-(1,5-dimethylpyrazol-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
CID 135344388
cis-(1R,2R)-N-[8-amino-6-(3,4-dihydro-2H-1,4-benzoxazin-8-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
CID 157087110
N-[8-amino-6-[6-[(3S)-3-aminopyrrolidin-1-yl]-4-methyl-3-pyridinyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
CID 135344394
4-[1-amino-6-[[(1R,2R)-2-fluorocyclopropanecarbonyl]amino]-2,7-naphthyridin-3-yl]-3-methylbenzamide
CID 139468854
N-[8-amino-6-(2-ethylphenyl)-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide
CID 158576696
N-[8-amino-6-[2-(hydroxymethyl)-5-methyl-4-pyridinyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
CID 135344858
cis-(1R,2R)-N-[8-amino-6-[6-(2-hydroxypropan-2-yl)-4-methyl-3-pyridinyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[6-(2-hydroxypropan-2-yl)-4-methyl-3-pyridinyl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
CID 157171811
N-[8-amino-6-(4-ethyl-3-pyridinyl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide
CID 135344454
N-[8-amino-6-(3-amino-2-methylphenyl)-2,7-naphthyridin-3-yl]cyclopropanecarboxamide
CID 142447326
cis-(1S,2S)-N-[8-amino-6-(2,3-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide
CID 135345077

Frequently Asked Questions

What is the IUPAC name of cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide?
The IUPAC name of cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide (CID 157459300) is cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide.
What is the SMILES notation for cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide?
The canonical SMILES for cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide is CC[C@@H]1CCCN1c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1.CC[C@H]1CCCN1c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1.CC[C@H]1CCCN1c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1.CCc1cc(OC)ncc1-c1cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc2c(N)n1.CCc1cc(OC)ncc1-c1cc2cc(NC(=O)[C@H]3C[C@H]3F)ncc2c(N)n1.Cn1ccc2cccc(-c3cc4cc(NC(=O)[C@@H]5C[C@@H]5F)ncc4c(N)n3)c21.
What is the InChIKey of cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide?
The InChIKey is BTSSUZYGQQTRNV-WUXASEMTSA-N. The full InChI is InChI=1S/C21H18FN5O.2C20H20FN5O2.3C18H22FN5O/c1-27-6-5-11-3-2-4-13(19(11)27)17-7-12-8-18(24-10-15(12)20(23)25-17)26-21(28)14-9-16(14)22;2*1-3-10-6-18(28-2)24-8-13(10)16-4-11-5-17(23-9-14(11)19(22)25-16)26-20(27)12-7-15(12)21;3*1-2-11-4-3-5-24(11)16-7-10-6-15(21-9-13(10)17(20)23-16)22-18(25)12-8-14(12)19/h2-8,10,14,16H,9H2,1H3,(H2,23,25)(H,24,26,28);2*4-6,8-9,12,15H,3,7H2,1-2H3,(H2,22,25)(H,23,26,27);3*6-7,9,11-12,14H,2-5,8H2,1H3,(H2,20,23)(H,21,22,25)/t14-,16+;2*12-,15+;2*11-,12+,14-;11-,12-,14+/m110100/s1.
What are the key properties of cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide?
cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide has a molecular weight of 2168.45 g/mol, XLogP of 18.61, 25 rotatable bonds, 12 hydrogen bond donors, and 32 hydrogen bond acceptors.
Where does this data come from?
All data for cis-(1R,2R)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(4-ethyl-6-methoxy-3-pyridinyl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2R)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1R,2R)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-ethylpyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-(1-methylindol-7-yl)-2,7-naphthyridin-3-yl]-2-fluorocyclopropane-1-carboxamide is sourced from PubChem (CID 157459300), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).