N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine

C93H60F23N27OS — CID 157463478

About N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine

N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine (PubChem CID 157463478) has the molecular formula C93H60F23N27OS and a molecular weight of 2040.71 g/mol. Its IUPAC name is N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine.

Molecular Properties

• Compound Name: N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine
• PubChem CID: 157463478
• Molecular Formula: C93H60F23N27OS
• Molecular Weight: 2040.71 g/mol
• Exact Mass: 2039.48
• IUPAC Name: N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine
• SMILES: CSc1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4ccccn34)n2)cc1.Cc1nc2ccccc2n1-c1cncc(Nc2ccc(C(F)(F)F)nc2)n1.FC(F)(F)c1ccc(Nc2cccc(-c3c(C(F)(F)F)nc4ccccn34)n2)cn1.FC(F)(F)c1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4ccccn34)n2)cn1.FC(F)Oc1ccc(Nc2cncc(-c3c(C(F)(F)F)nn4ccccc34)n2)cc1
• InChI: InChI=1S/C19H11F6N5.C19H12F5N5O.C19H14F3N5S.C18H10F6N6.C18H13F3N6/c20-18(21,22)13-8-7-11(10-26-13)27-14-5-3-4-12(28-14)16-17(19(23,24)25)29-15-6-1-2-9-30(15)16;20-18(21)30-12-6-4-11(5-7-12)26-15-10-25-9-13(27-15)16-14-3-1-2-8-29(14)28-17(16)19(22,23)24;1-28-13-7-5-12(6-8-13)24-15-11-23-10-14(25-15)17-18(19(20,21)22)26-16-4-2-3-9-27(16)17;19-17(20,21)12-5-4-10(7-26-12)27-13-9-25-8-11(28-13)15-16(18(22,23)24)29-14-3-1-2-6-30(14)15;1-11-24-13-4-2-3-5-14(13)27(11)17-10-22-9-16(26-17)25-12-6-7-15(23-8-12)18(19,20)21/h1-10H,(H,27,28);1-10,18H,(H,26,27);2-11H,1H3,(H,24,25);1-9H,(H,27,28);2-10H,1H3,(H,25,26)
• InChIKey: BUEUZQISDNSWRP-UHFFFAOYSA-N
• XLogP: 25.25
• TPSA: 311.08 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 29
• Rotatable Bonds: 18
• Heavy Atoms: 145
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2040.71
LogP ≤ 5	25.25
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	29

Frequently Asked Questions

What is the IUPAC name of N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine?

The IUPAC name of N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine (CID 157463478) is N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine.

What is the SMILES notation for N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine?

The canonical SMILES for N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine is CSc1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4ccccn34)n2)cc1.Cc1nc2ccccc2n1-c1cncc(Nc2ccc(C(F)(F)F)nc2)n1.FC(F)(F)c1ccc(Nc2cccc(-c3c(C(F)(F)F)nc4ccccn34)n2)cn1.FC(F)(F)c1ccc(Nc2cncc(-c3c(C(F)(F)F)nc4ccccn34)n2)cn1.FC(F)Oc1ccc(Nc2cncc(-c3c(C(F)(F)F)nn4ccccc34)n2)cc1.

What is the InChIKey of N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine?

The InChIKey is BUEUZQISDNSWRP-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H11F6N5.C19H12F5N5O.C19H14F3N5S.C18H10F6N6.C18H13F3N6/c20-18(21,22)13-8-7-11(10-26-13)27-14-5-3-4-12(28-14)16-17(19(23,24)25)29-15-6-1-2-9-30(15)16;20-18(21)30-12-6-4-11(5-7-12)26-15-10-25-9-13(27-15)16-14-3-1-2-8-29(14)28-17(16)19(22,23)24;1-28-13-7-5-12(6-8-13)24-15-11-23-10-14(25-15)17-18(19(20,21)22)26-16-4-2-3-9-27(16)17;19-17(20,21)12-5-4-10(7-26-12)27-13-9-25-8-11(28-13)15-16(18(22,23)24)29-14-3-1-2-6-30(14)15;1-11-24-13-4-2-3-5-14(13)27(11)17-10-22-9-16(26-17)25-12-6-7-15(23-8-12)18(19,20)21/h1-10H,(H,27,28);1-10,18H,(H,26,27);2-11H,1H3,(H,24,25);1-9H,(H,27,28);2-10H,1H3,(H,25,26).

What are the key properties of N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine?

N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine has a molecular weight of 2040.71 g/mol, XLogP of 25.25, 18 rotatable bonds, 5 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for N-[4-(difluoromethoxy)phenyl]-6-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;N-(4-methylsulfanylphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyrazin-2-amine;6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine is sourced from PubChem (CID 157463478), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).