4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine

C99H122ClN15O11S3 — CID 157469558

About 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine

4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine (PubChem CID 157469558) has the molecular formula C99H122ClN15O11S3 and a molecular weight of 1829.81 g/mol. Its IUPAC name is 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine.

Molecular Properties

• Compound Name: 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine
• PubChem CID: 157469558
• Molecular Formula: C99H122ClN15O11S3
• Molecular Weight: 1829.81 g/mol
• Exact Mass: 1827.83
• IUPAC Name: 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine
• SMILES: COCCOc1ccc2c(OC(C)(C)C)cc(-c3csc(NC(C)C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-c3csc(NC(C)C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-c3csc(NC(C)C)n3)nc2c1Cl.COc1ccc2c(OC(C)(C)C)cc(-n3ccc(C(C)C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-n3cccn3)nc2c1
• InChI: InChI=1S/C22H29N3O3S.C20H24ClN3O2S.C20H25N3O2S.C20H25N3O2.C17H19N3O2/c1-14(2)23-21-25-19(13-29-21)18-12-20(28-22(3,4)5)16-8-7-15(11-17(16)24-18)27-10-9-26-6;1-11(2)22-19-24-14(10-27-19)13-9-16(26-20(3,4)5)12-7-8-15(25-6)17(21)18(12)23-13;1-12(2)21-19-23-17(11-26-19)16-10-18(25-20(3,4)5)14-8-7-13(24-6)9-15(14)22-16;1-13(2)16-9-10-23(22-16)19-12-18(25-20(3,4)5)15-8-7-14(24-6)11-17(15)21-19;1-17(2,3)22-15-11-16(20-9-5-8-18-20)19-14-10-12(21-4)6-7-13(14)15/h7-8,11-14H,9-10H2,1-6H3,(H,23,25);7-11H,1-6H3,(H,22,24);7-12H,1-6H3,(H,21,23);7-13H,1-6H3;5-11H,1-4H3
• InChIKey: BUWGMXVUAVOPSC-UHFFFAOYSA-N
• XLogP: 25.10
• TPSA: 276.38 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 29
• Rotatable Bonds: 25
• Heavy Atoms: 129
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1829.81
LogP ≤ 5	25.10
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine?

The IUPAC name of 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine (CID 157469558) is 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine.

What is the SMILES notation for 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine?

The canonical SMILES for 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine is COCCOc1ccc2c(OC(C)(C)C)cc(-c3csc(NC(C)C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-c3csc(NC(C)C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-c3csc(NC(C)C)n3)nc2c1Cl.COc1ccc2c(OC(C)(C)C)cc(-n3ccc(C(C)C)n3)nc2c1.COc1ccc2c(OC(C)(C)C)cc(-n3cccn3)nc2c1.

What is the InChIKey of 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine?

The InChIKey is BUWGMXVUAVOPSC-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H29N3O3S.C20H24ClN3O2S.C20H25N3O2S.C20H25N3O2.C17H19N3O2/c1-14(2)23-21-25-19(13-29-21)18-12-20(28-22(3,4)5)16-8-7-15(11-17(16)24-18)27-10-9-26-6;1-11(2)22-19-24-14(10-27-19)13-9-16(26-20(3,4)5)12-7-8-15(25-6)17(21)18(12)23-13;1-12(2)21-19-23-17(11-26-19)16-10-18(25-20(3,4)5)14-8-7-13(24-6)9-15(14)22-16;1-13(2)16-9-10-23(22-16)19-12-18(25-20(3,4)5)15-8-7-14(24-6)11-17(15)21-19;1-17(2,3)22-15-11-16(20-9-5-8-18-20)19-14-10-12(21-4)6-7-13(14)15/h7-8,11-14H,9-10H2,1-6H3,(H,23,25);7-11H,1-6H3,(H,22,24);7-12H,1-6H3,(H,21,23);7-13H,1-6H3;5-11H,1-4H3.

What are the key properties of 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine?

4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine has a molecular weight of 1829.81 g/mol, XLogP of 25.10, 25 rotatable bonds, 3 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 4-[8-chloro-7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;4-[7-(2-methoxyethoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-(3-propan-2-ylpyrazol-1-yl)quinoline;7-methoxy-4-[(2-methylpropan-2-yl)oxy]-2-pyrazol-1-ylquinoline;4-[7-methoxy-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine is sourced from PubChem (CID 157469558), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).