N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane

C105H129Cl3F7N27O7S — CID 158048684

About N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane (PubChem CID 158048684) has the molecular formula C105H129Cl3F7N27O7S and a molecular weight of 2152.78 g/mol. Its IUPAC name is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane.

Molecular Properties

• Compound Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane
• PubChem CID: 158048684
• Molecular Formula: C105H129Cl3F7N27O7S
• Molecular Weight: 2152.78 g/mol
• Exact Mass: 2149.92
• IUPAC Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane
• SMILES: C.C.CC(C)(C)CC(=O)Nc1nc2ccc(CO)nc2n1CC(F)(F)F.CC(CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1)CC(F)(F)F.CC1(F)CCC(CC(=O)Nc2nc3ccc(Cl)nc3n2C2CCC2)CC1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCc3nccs3)n(C3CCC3)c2n1.Cn1cc(-n2c(NC(=O)CCc3ccccc3)nc3ccc(Cl)nc32)cn1
• InChI: InChI=1S/C19H24ClFN4O.C19H17ClN6O.C17H19N5OS.C17H24N4O.C16H18ClF3N4O.C15H19F3N4O2.2CH4/c1-19(21)9-7-12(8-10-19)11-16(26)24-18-22-14-5-6-15(20)23-17(14)25(18)13-3-2-4-13;1-25-12-14(11-21-25)26-18-15(8-9-16(20)23-18)22-19(26)24-17(27)10-7-13-5-3-2-4-6-13;1-11-5-6-13-16(19-11)22(12-3-2-4-12)17(20-13)21-14(23)7-8-15-18-9-10-24-15;1-11-8-9-13-15(18-11)21(12-6-5-7-12)16(19-13)20-14(22)10-17(2,3)4;1-9(8-16(18,19)20)7-13(25)23-15-21-11-5-6-12(17)22-14(11)24(15)10-3-2-4-10;1-14(2,3)6-11(24)21-13-20-10-5-4-9(7-23)19-12(10)22(13)8-15(16,17)18;;/h5-6,12-13H,2-4,7-11H2,1H3,(H,22,24,26);2-6,8-9,11-12H,7,10H2,1H3,(H,22,24,27);5-6,9-10,12H,2-4,7-8H2,1H3,(H,20,21,23);8-9,12H,5-7,10H2,1-4H3,(H,19,20,22);5-6,9-10H,2-4,7-8H2,1H3,(H,21,23,25);4-5,23H,6-8H2,1-3H3,(H,20,21,24);2*1H4
• InChIKey: FJFHEOGAHJXZCU-UHFFFAOYSA-N
• XLogP: 24.63
• TPSA: 409.80 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 29
• Rotatable Bonds: 26
• Heavy Atoms: 150
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2152.78
LogP ≤ 5	24.63
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane?

The IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane (CID 158048684) is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane.

What is the SMILES notation for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane?

The canonical SMILES for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane is C.C.CC(C)(C)CC(=O)Nc1nc2ccc(CO)nc2n1CC(F)(F)F.CC(CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1)CC(F)(F)F.CC1(F)CCC(CC(=O)Nc2nc3ccc(Cl)nc3n2C2CCC2)CC1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCc3nccs3)n(C3CCC3)c2n1.Cn1cc(-n2c(NC(=O)CCc3ccccc3)nc3ccc(Cl)nc32)cn1.

What is the InChIKey of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane?

The InChIKey is FJFHEOGAHJXZCU-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H24ClFN4O.C19H17ClN6O.C17H19N5OS.C17H24N4O.C16H18ClF3N4O.C15H19F3N4O2.2CH4/c1-19(21)9-7-12(8-10-19)11-16(26)24-18-22-14-5-6-15(20)23-17(14)25(18)13-3-2-4-13;1-25-12-14(11-21-25)26-18-15(8-9-16(20)23-18)22-19(26)24-17(27)10-7-13-5-3-2-4-6-13;1-11-5-6-13-16(19-11)22(12-3-2-4-12)17(20-13)21-14(23)7-8-15-18-9-10-24-15;1-11-8-9-13-15(18-11)21(12-6-5-7-12)16(19-13)20-14(22)10-17(2,3)4;1-9(8-16(18,19)20)7-13(25)23-15-21-11-5-6-12(17)22-14(11)24(15)10-3-2-4-10;1-14(2,3)6-11(24)21-13-20-10-5-4-9(7-23)19-12(10)22(13)8-15(16,17)18;;/h5-6,12-13H,2-4,7-11H2,1H3,(H,22,24,26);2-6,8-9,11-12H,7,10H2,1H3,(H,22,24,27);5-6,9-10,12H,2-4,7-8H2,1H3,(H,20,21,23);8-9,12H,5-7,10H2,1-4H3,(H,19,20,22);5-6,9-10H,2-4,7-8H2,1H3,(H,21,23,25);4-5,23H,6-8H2,1-3H3,(H,20,21,24);2*1H4.

What are the key properties of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane?

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane has a molecular weight of 2152.78 g/mol, XLogP of 24.63, 26 rotatable bonds, 7 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-2-(4-fluoro-4-methylcyclohexyl)acetamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-5,5,5-trifluoro-3-methylpentanamide;N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1,3-thiazol-2-yl)propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;methane is sourced from PubChem (CID 158048684), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).