N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide

C107H134ClF3N26O9 — CID 157062913

About N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide

N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide (PubChem CID 157062913) has the molecular formula C107H134ClF3N26O9 and a molecular weight of 2020.87 g/mol. Its IUPAC name is N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide.

Molecular Properties

• Compound Name: N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide
• PubChem CID: 157062913
• Molecular Formula: C107H134ClF3N26O9
• Molecular Weight: 2020.87 g/mol
• Exact Mass: 2019.05
• IUPAC Name: N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide
• SMILES: CC(C)(C)CC(=O)Nc1nc2ccc(CO)nc2n1CC(F)(F)F.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CC3C[C@]4(C)CCO[C@H]34)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCC3(C)CC3)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CC[C@@H]3CCCO3)n(C3CCC3)c2n1.Cn1cc(-n2c(NC(=O)CCc3ccccc3)nc3ccc(Cl)nc32)cn1
• InChI: InChI=1S/C20H26N4O2.C19H17ClN6O.C18H24N4O2.C18H24N4O.C17H24N4O.C15H19F3N4O2/c1-12-6-7-15-18(21-12)24(14-4-3-5-14)19(22-15)23-16(25)10-13-11-20(2)8-9-26-17(13)20;1-25-12-14(11-21-25)26-18-15(8-9-16(20)23-18)22-19(26)24-17(27)10-7-13-5-3-2-4-6-13;1-12-7-9-15-17(19-12)22(13-4-2-5-13)18(20-15)21-16(23)10-8-14-6-3-11-24-14;1-12-6-7-14-16(19-12)22(13-4-3-5-13)17(20-14)21-15(23)8-9-18(2)10-11-18;1-11-8-9-13-15(18-11)21(12-6-5-7-12)16(19-13)20-14(22)10-17(2,3)4;1-14(2,3)6-11(24)21-13-20-10-5-4-9(7-23)19-12(10)22(13)8-15(16,17)18/h6-7,13-14,17H,3-5,8-11H2,1-2H3,(H,22,23,25);2-6,8-9,11-12H,7,10H2,1H3,(H,22,24,27);7,9,13-14H,2-6,8,10-11H2,1H3,(H,20,21,23);6-7,13H,3-5,8-11H2,1-2H3,(H,20,21,23);8-9,12H,5-7,10H2,1-4H3,(H,19,20,22);4-5,23H,6-8H2,1-3H3,(H,20,21,24)/t13?,17-,20+;;14-;;;/m1.0.../s1
• InChIKey: ABNMPIQJEOQIIH-JFNABUCQSA-N
• XLogP: 21.03
• TPSA: 415.37 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 29
• Rotatable Bonds: 26
• Heavy Atoms: 146
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2020.87
LogP ≤ 5	21.03
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

The IUPAC name of N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide (CID 157062913) is N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide.

What is the SMILES notation for N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

The canonical SMILES for N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide is CC(C)(C)CC(=O)Nc1nc2ccc(CO)nc2n1CC(F)(F)F.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CC3C[C@]4(C)CCO[C@H]34)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCC3(C)CC3)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CC[C@@H]3CCCO3)n(C3CCC3)c2n1.Cn1cc(-n2c(NC(=O)CCc3ccccc3)nc3ccc(Cl)nc32)cn1.

What is the InChIKey of N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

The InChIKey is ABNMPIQJEOQIIH-JFNABUCQSA-N. The full InChI is InChI=1S/C20H26N4O2.C19H17ClN6O.C18H24N4O2.C18H24N4O.C17H24N4O.C15H19F3N4O2/c1-12-6-7-15-18(21-12)24(14-4-3-5-14)19(22-15)23-16(25)10-13-11-20(2)8-9-26-17(13)20;1-25-12-14(11-21-25)26-18-15(8-9-16(20)23-18)22-19(26)24-17(27)10-7-13-5-3-2-4-6-13;1-12-7-9-15-17(19-12)22(13-4-2-5-13)18(20-15)21-16(23)10-8-14-6-3-11-24-14;1-12-6-7-14-16(19-12)22(13-4-3-5-13)17(20-14)21-15(23)8-9-18(2)10-11-18;1-11-8-9-13-15(18-11)21(12-6-5-7-12)16(19-13)20-14(22)10-17(2,3)4;1-14(2,3)6-11(24)21-13-20-10-5-4-9(7-23)19-12(10)22(13)8-15(16,17)18/h6-7,13-14,17H,3-5,8-11H2,1-2H3,(H,22,23,25);2-6,8-9,11-12H,7,10H2,1H3,(H,22,24,27);7,9,13-14H,2-6,8,10-11H2,1H3,(H,20,21,23);6-7,13H,3-5,8-11H2,1-2H3,(H,20,21,23);8-9,12H,5-7,10H2,1-4H3,(H,19,20,22);4-5,23H,6-8H2,1-3H3,(H,20,21,24)/t13?,17-,20+;;14-;;;/m1.0.../s1.

What are the key properties of N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide has a molecular weight of 2020.87 g/mol, XLogP of 21.03, 26 rotatable bonds, 7 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-chloro-3-(1-methylpyrazol-4-yl)imidazo[4,5-b]pyridin-2-yl]-3-phenylpropanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(1-methylcyclopropyl)propanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-[(1R,5R)-5-methyl-2-oxabicyclo[3.2.0]heptan-7-yl]acetamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-[(2S)-oxolan-2-yl]propanamide;N-[5-(hydroxymethyl)-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide is sourced from PubChem (CID 157062913), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).