N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide

C111H139Cl2F3N24O9 — CID 158945582

About N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide

N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide (PubChem CID 158945582) has the molecular formula C111H139Cl2F3N24O9 and a molecular weight of 2081.39 g/mol. Its IUPAC name is N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide.

Molecular Properties

• Compound Name: N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide
• PubChem CID: 158945582
• Molecular Formula: C111H139Cl2F3N24O9
• Molecular Weight: 2081.39 g/mol
• Exact Mass: 2079.05
• IUPAC Name: N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide
• SMILES: CCC(C)(C)[C@H](C)C(=O)Nc1nc2ccc(C(F)(F)F)nc2n1C1CCC1.Cc1cc(Cl)nc2c1nc(NC(=O)CC(C)(C)C)n2C1CCC1.Cc1cc(Cl)nc2c1nc(NC(=O)CC(C)(C)O)n2C1CCC1.Cc1ccc2nc(NC(=O)C[C@@H](O)c3ccccc3)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)C[C@H](O)c3ccccc3)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)[C@@H](C)C3(C)CCC3)n(C3CCC3)c2n1
• InChI: InChI=1S/2C20H22N4O2.C19H25F3N4O.C19H26N4O.C17H23ClN4O.C16H21ClN4O2/c2*1-13-10-11-16-19(21-13)24(15-8-5-9-15)20(22-16)23-18(26)12-17(25)14-6-3-2-4-7-14;1-5-18(3,4)11(2)16(27)25-17-23-13-9-10-14(19(20,21)22)24-15(13)26(17)12-7-6-8-12;1-12-8-9-15-16(20-12)23(14-6-4-7-14)18(21-15)22-17(24)13(2)19(3)10-5-11-19;1-10-8-12(18)19-15-14(10)21-16(22(15)11-6-5-7-11)20-13(23)9-17(2,3)4;1-9-7-11(17)18-14-13(9)20-15(21(14)10-5-4-6-10)19-12(22)8-16(2,3)23/h2*2-4,6-7,10-11,15,17,25H,5,8-9,12H2,1H3,(H,22,23,26);9-12H,5-8H2,1-4H3,(H,23,25,27);8-9,13-14H,4-7,10-11H2,1-3H3,(H,21,22,24);8,11H,5-7,9H2,1-4H3,(H,20,21,23);7,10,23H,4-6,8H2,1-3H3,(H,19,20,22)/t2*17-;11-;13-;;/m1011../s1
• InChIKey: JKTZTGWKAXXAIN-PLSCWSNCSA-N
• XLogP: 24.18
• TPSA: 419.55 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 27
• Rotatable Bonds: 26
• Heavy Atoms: 149
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2081.39
LogP ≤ 5	24.18
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	27

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide?

The IUPAC name of N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide (CID 158945582) is N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide.

What is the SMILES notation for N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide?

The canonical SMILES for N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide is CCC(C)(C)[C@H](C)C(=O)Nc1nc2ccc(C(F)(F)F)nc2n1C1CCC1.Cc1cc(Cl)nc2c1nc(NC(=O)CC(C)(C)C)n2C1CCC1.Cc1cc(Cl)nc2c1nc(NC(=O)CC(C)(C)O)n2C1CCC1.Cc1ccc2nc(NC(=O)C[C@@H](O)c3ccccc3)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)C[C@H](O)c3ccccc3)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)[C@@H](C)C3(C)CCC3)n(C3CCC3)c2n1.

What is the InChIKey of N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide?

The InChIKey is JKTZTGWKAXXAIN-PLSCWSNCSA-N. The full InChI is InChI=1S/2C20H22N4O2.C19H25F3N4O.C19H26N4O.C17H23ClN4O.C16H21ClN4O2/c2*1-13-10-11-16-19(21-13)24(15-8-5-9-15)20(22-16)23-18(26)12-17(25)14-6-3-2-4-7-14;1-5-18(3,4)11(2)16(27)25-17-23-13-9-10-14(19(20,21)22)24-15(13)26(17)12-7-6-8-12;1-12-8-9-15-16(20-12)23(14-6-4-7-14)18(21-15)22-17(24)13(2)19(3)10-5-11-19;1-10-8-12(18)19-15-14(10)21-16(22(15)11-6-5-7-11)20-13(23)9-17(2,3)4;1-9-7-11(17)18-14-13(9)20-15(21(14)10-5-4-6-10)19-12(22)8-16(2,3)23/h2*2-4,6-7,10-11,15,17,25H,5,8-9,12H2,1H3,(H,22,23,26);9-12H,5-8H2,1-4H3,(H,23,25,27);8-9,13-14H,4-7,10-11H2,1-3H3,(H,21,22,24);8,11H,5-7,9H2,1-4H3,(H,20,21,23);7,10,23H,4-6,8H2,1-3H3,(H,19,20,22)/t2*17-;11-;13-;;/m1011../s1.

What are the key properties of N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide?

N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide has a molecular weight of 2081.39 g/mol, XLogP of 24.18, 26 rotatable bonds, 9 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3,3-dimethylbutanamide;N-(5-chloro-3-cyclobutyl-7-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;(3R)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(3S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpropanamide;(2S)-N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-2-(1-methylcyclobutyl)propanamide;(2S)-N-[3-cyclobutyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-2,3,3-trimethylpentanamide is sourced from PubChem (CID 158945582), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).