2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one

C225H206F11N51O24S3 — CID 158116897

IUPAC2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one
SMILESCN1C(=O)C(c2cc(OC3CC3)cc(-c3ccn[nH]3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3ccoc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3ccon3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3ccsc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cnc(F)nc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cnco3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cncs3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cocn3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cscn3)c2)(c2ccnc(CF)c2)N=C1N.Cc1ncc(-c2cc(OC3CC3)cc(C3(c4ccnc(CF)c4)N=C(N)N(C)C3=O)c2)cn1
InChIInChI=1S/C24H23FN6O2.C23H20F2N6O2.C23H21FN4O3.C23H21FN4O2S.C22H21FN6O2.3C22H20FN5O3.2C22H20FN5O2S/c1-14-28-12-16(13-29-14)15-7-18(10-21(8-15)33-20-3-4-20)24(22(32)31(2)23(26)30-24)17-5-6-27-19(9-17)11-25;1-31-20(32)23(30-22(31)26,15-4-5-27-17(8-15)10-24)16-6-13(14-11-28-21(25)29-12-14)7-19(9-16)33-18-2-3-18;1-28-21(29)23(27-22(28)25,16-4-6-26-18(10-16)12-24)17-8-15(14-5-7-30-13-14)9-20(11-17)31-19-2-3-19;1-28-21(29)23(27-22(28)25,16-4-6-26-18(10-16)12-24)17-8-15(14-5-7-31-13-14)9-20(11-17)30-19-2-3-19;1-29-20(30)22(27-21(29)24,14-4-6-25-16(10-14)12-23)15-8-13(19-5-7-26-28-19)9-18(11-15)31-17-2-3-17;1-28-20(29)22(26-21(28)24,14-4-6-25-16(10-14)12-23)15-8-13(19-5-7-30-27-19)9-18(11-15)31-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-26-16(8-14)10-23)15-6-13(19-11-25-12-30-19)7-18(9-15)31-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-25-16(8-14)10-23)15-6-13(19-11-30-12-26-19)7-18(9-15)31-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-26-16(8-14)10-23)15-6-13(19-11-25-12-31-19)7-18(9-15)30-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-25-16(8-14)10-23)15-6-13(19-11-31-12-26-19)7-18(9-15)30-17-2-3-17/h5-10,12-13,20H,3-4,11H2,1-2H3,(H2,26,30);4-9,11-12,18H,2-3,10H2,1H3,(H2,26,30);2*4-11,13,19H,2-3,12H2,1H3,(H2,25,27);4-11,17H,2-3,12H2,1H3,(H2,24,27)(H,26,28);4-11,17H,2-3,12H2,1H3,(H2,24,26);4*4-9,11-12,17H,2-3,10H2,1H3,(H2,24,27)
InChIKeyFRCVEHDHRUBZJN-UHFFFAOYSA-N
MW4313.63 g/mol
LogP30.18
Rot. Bonds60

About 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one

2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one (PubChem CID 158116897) has the molecular formula C225H206F11N51O24S3 and a molecular weight of 4313.63 g/mol. Its IUPAC name is 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one.

Molecular Properties

Compound Name2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one
PubChem CID158116897
Molecular FormulaC225H206F11N51O24S3
Molecular Weight4313.63 g/mol
Exact Mass4310.55
IUPAC Name2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one
SMILESCN1C(=O)C(c2cc(OC3CC3)cc(-c3ccn[nH]3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3ccoc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3ccon3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3ccsc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cnc(F)nc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cnco3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cncs3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cocn3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cscn3)c2)(c2ccnc(CF)c2)N=C1N.Cc1ncc(-c2cc(OC3CC3)cc(C3(c4ccnc(CF)c4)N=C(N)N(C)C3=O)c2)cn1
InChIInChI=1S/C24H23FN6O2.C23H20F2N6O2.C23H21FN4O3.C23H21FN4O2S.C22H21FN6O2.3C22H20FN5O3.2C22H20FN5O2S/c1-14-28-12-16(13-29-14)15-7-18(10-21(8-15)33-20-3-4-20)24(22(32)31(2)23(26)30-24)17-5-6-27-19(9-17)11-25;1-31-20(32)23(30-22(31)26,15-4-5-27-17(8-15)10-24)16-6-13(14-11-28-21(25)29-12-14)7-19(9-16)33-18-2-3-18;1-28-21(29)23(27-22(28)25,16-4-6-26-18(10-16)12-24)17-8-15(14-5-7-30-13-14)9-20(11-17)31-19-2-3-19;1-28-21(29)23(27-22(28)25,16-4-6-26-18(10-16)12-24)17-8-15(14-5-7-31-13-14)9-20(11-17)30-19-2-3-19;1-29-20(30)22(27-21(29)24,14-4-6-25-16(10-14)12-23)15-8-13(19-5-7-26-28-19)9-18(11-15)31-17-2-3-17;1-28-20(29)22(26-21(28)24,14-4-6-25-16(10-14)12-23)15-8-13(19-5-7-30-27-19)9-18(11-15)31-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-26-16(8-14)10-23)15-6-13(19-11-25-12-30-19)7-18(9-15)31-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-25-16(8-14)10-23)15-6-13(19-11-30-12-26-19)7-18(9-15)31-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-26-16(8-14)10-23)15-6-13(19-11-25-12-31-19)7-18(9-15)30-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-25-16(8-14)10-23)15-6-13(19-11-31-12-26-19)7-18(9-15)30-17-2-3-17/h5-10,12-13,20H,3-4,11H2,1-2H3,(H2,26,30);4-9,11-12,18H,2-3,10H2,1H3,(H2,26,30);2*4-11,13,19H,2-3,12H2,1H3,(H2,25,27);4-11,17H,2-3,12H2,1H3,(H2,24,27)(H,26,28);4-11,17H,2-3,12H2,1H3,(H2,24,26);4*4-9,11-12,17H,2-3,10H2,1H3,(H2,24,27)
InChIKeyFRCVEHDHRUBZJN-UHFFFAOYSA-N
XLogP30.18
TPSA1005.35 Ų
H-Bond Donors11
H-Bond Acceptors67
Rotatable Bonds60
Heavy Atoms314
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004313.63
LogP ≤ 530.18
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1067

Analyze 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one?
The IUPAC name of 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one (CID 158116897) is 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one.
What is the SMILES notation for 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one?
The canonical SMILES for 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one is CN1C(=O)C(c2cc(OC3CC3)cc(-c3ccn[nH]3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3ccoc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3ccon3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3ccsc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cnc(F)nc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cnco3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cncs3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cocn3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(OC3CC3)cc(-c3cscn3)c2)(c2ccnc(CF)c2)N=C1N.Cc1ncc(-c2cc(OC3CC3)cc(C3(c4ccnc(CF)c4)N=C(N)N(C)C3=O)c2)cn1.
What is the InChIKey of 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one?
The InChIKey is FRCVEHDHRUBZJN-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H23FN6O2.C23H20F2N6O2.C23H21FN4O3.C23H21FN4O2S.C22H21FN6O2.3C22H20FN5O3.2C22H20FN5O2S/c1-14-28-12-16(13-29-14)15-7-18(10-21(8-15)33-20-3-4-20)24(22(32)31(2)23(26)30-24)17-5-6-27-19(9-17)11-25;1-31-20(32)23(30-22(31)26,15-4-5-27-17(8-15)10-24)16-6-13(14-11-28-21(25)29-12-14)7-19(9-16)33-18-2-3-18;1-28-21(29)23(27-22(28)25,16-4-6-26-18(10-16)12-24)17-8-15(14-5-7-30-13-14)9-20(11-17)31-19-2-3-19;1-28-21(29)23(27-22(28)25,16-4-6-26-18(10-16)12-24)17-8-15(14-5-7-31-13-14)9-20(11-17)30-19-2-3-19;1-29-20(30)22(27-21(29)24,14-4-6-25-16(10-14)12-23)15-8-13(19-5-7-26-28-19)9-18(11-15)31-17-2-3-17;1-28-20(29)22(26-21(28)24,14-4-6-25-16(10-14)12-23)15-8-13(19-5-7-30-27-19)9-18(11-15)31-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-26-16(8-14)10-23)15-6-13(19-11-25-12-30-19)7-18(9-15)31-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-25-16(8-14)10-23)15-6-13(19-11-30-12-26-19)7-18(9-15)31-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-26-16(8-14)10-23)15-6-13(19-11-25-12-31-19)7-18(9-15)30-17-2-3-17;1-28-20(29)22(27-21(28)24,14-4-5-25-16(8-14)10-23)15-6-13(19-11-31-12-26-19)7-18(9-15)30-17-2-3-17/h5-10,12-13,20H,3-4,11H2,1-2H3,(H2,26,30);4-9,11-12,18H,2-3,10H2,1H3,(H2,26,30);2*4-11,13,19H,2-3,12H2,1H3,(H2,25,27);4-11,17H,2-3,12H2,1H3,(H2,24,27)(H,26,28);4-11,17H,2-3,12H2,1H3,(H2,24,26);4*4-9,11-12,17H,2-3,10H2,1H3,(H2,24,27).
What are the key properties of 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one?
2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one has a molecular weight of 4313.63 g/mol, XLogP of 30.18, 60 rotatable bonds, 11 hydrogen bond donors, and 67 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-5-[3-cyclopropyloxy-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-cyclopropyloxy-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-cyclopropyloxy-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one is sourced from PubChem (CID 158116897), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).