N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine

C87H83F7N18O3S4 — CID 158129323

About N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine

N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine (PubChem CID 158129323) has the molecular formula C87H83F7N18O3S4 and a molecular weight of 1690.00 g/mol. Its IUPAC name is N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine.

Molecular Properties

• Compound Name: N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine
• PubChem CID: 158129323
• Molecular Formula: C87H83F7N18O3S4
• Molecular Weight: 1690.00 g/mol
• Exact Mass: 1688.57
• IUPAC Name: N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine
• SMILES: CCOCC(C)Nc1ncc(-c2cc(-c3ccc(C#N)cc3)c3nccn3c2)s1.CCOCC(C)Nc1ncc(-c2cc(-c3ccc(C(F)(F)F)cc3)c3nccn3c2)s1.CC[C@@H](C)Nc1ncc(-c2cc(-c3ccc(C(F)(F)F)cc3)c3nccn3c2)s1.Fc1ccccc1-c1cc(-c2cnc(NCCN3CCOCC3)s2)cn2ccnc12
• InChI: InChI=1S/C22H21F3N4OS.C22H22FN5OS.C22H21N5OS.C21H19F3N4S/c1-3-30-13-14(2)28-21-27-11-19(31-21)16-10-18(20-26-8-9-29(20)12-16)15-4-6-17(7-5-15)22(23,24)25;23-19-4-2-1-3-17(19)18-13-16(15-28-8-6-24-21(18)28)20-14-26-22(30-20)25-5-7-27-9-11-29-12-10-27;1-3-28-14-15(2)26-22-25-12-20(29-22)18-10-19(21-24-8-9-27(21)13-18)17-6-4-16(11-23)5-7-17;1-3-13(2)27-20-26-11-18(29-20)15-10-17(19-25-8-9-28(19)12-15)14-4-6-16(7-5-14)21(22,23)24/h4-12,14H,3,13H2,1-2H3,(H,27,28);1-4,6,8,13-15H,5,7,9-12H2,(H,25,26);4-10,12-13,15H,3,14H2,1-2H3,(H,25,26);4-13H,3H2,1-2H3,(H,26,27)/t;;;13-/m...1/s1
• InChIKey: FSOPBAUUSLWJTH-AQVMYGSESA-N
• XLogP: 21.18
• TPSA: 223.60 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 25
• Rotatable Bonds: 25
• Heavy Atoms: 119
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1690.00
LogP ≤ 5	21.18
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine?

The IUPAC name of N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine (CID 158129323) is N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine.

What is the SMILES notation for N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine?

The canonical SMILES for N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine is CCOCC(C)Nc1ncc(-c2cc(-c3ccc(C#N)cc3)c3nccn3c2)s1.CCOCC(C)Nc1ncc(-c2cc(-c3ccc(C(F)(F)F)cc3)c3nccn3c2)s1.CC[C@@H](C)Nc1ncc(-c2cc(-c3ccc(C(F)(F)F)cc3)c3nccn3c2)s1.Fc1ccccc1-c1cc(-c2cnc(NCCN3CCOCC3)s2)cn2ccnc12.

What is the InChIKey of N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine?

The InChIKey is FSOPBAUUSLWJTH-AQVMYGSESA-N. The full InChI is InChI=1S/C22H21F3N4OS.C22H22FN5OS.C22H21N5OS.C21H19F3N4S/c1-3-30-13-14(2)28-21-27-11-19(31-21)16-10-18(20-26-8-9-29(20)12-16)15-4-6-17(7-5-15)22(23,24)25;23-19-4-2-1-3-17(19)18-13-16(15-28-8-6-24-21(18)28)20-14-26-22(30-20)25-5-7-27-9-11-29-12-10-27;1-3-28-14-15(2)26-22-25-12-20(29-22)18-10-19(21-24-8-9-27(21)13-18)17-6-4-16(11-23)5-7-17;1-3-13(2)27-20-26-11-18(29-20)15-10-17(19-25-8-9-28(19)12-15)14-4-6-16(7-5-14)21(22,23)24/h4-12,14H,3,13H2,1-2H3,(H,27,28);1-4,6,8,13-15H,5,7,9-12H2,(H,25,26);4-10,12-13,15H,3,14H2,1-2H3,(H,25,26);4-13H,3H2,1-2H3,(H,26,27)/t;;;13-/m...1/s1.

What are the key properties of N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine?

N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine has a molecular weight of 1690.00 g/mol, XLogP of 21.18, 25 rotatable bonds, 4 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;4-[6-[2-(1-ethoxypropan-2-ylamino)-1,3-thiazol-5-yl]imidazo[1,2-a]pyridin-8-yl]benzonitrile;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;5-[8-(2-fluorophenyl)imidazo[1,2-a]pyridin-6-yl]-N-(2-morpholin-4-ylethyl)-1,3-thiazol-2-amine is sourced from PubChem (CID 158129323), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).