5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine

C65H65F6N13O2S3 — CID 161081937

About 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine

5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine (PubChem CID 161081937) has the molecular formula C65H65F6N13O2S3 and a molecular weight of 1270.51 g/mol. Its IUPAC name is 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine.

Molecular Properties

• Compound Name: 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine
• PubChem CID: 161081937
• Molecular Formula: C65H65F6N13O2S3
• Molecular Weight: 1270.51 g/mol
• Exact Mass: 1269.45
• IUPAC Name: 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine
• SMILES: CCOCC(C)Nc1ncc(-c2cc(-c3ccc(C(F)(F)F)cc3)c3nccn3c2)s1.CCOCC(C)Nc1ncc(-c2cc(-c3ccc(CN)cc3)c3nccn3c2)s1.CC[C@@H](C)Nc1ncc(-c2cc(-c3ccc(C(F)(F)F)cc3)c3nccn3c2)s1
• InChI: InChI=1S/C22H21F3N4OS.C22H25N5OS.C21H19F3N4S/c1-3-30-13-14(2)28-21-27-11-19(31-21)16-10-18(20-26-8-9-29(20)12-16)15-4-6-17(7-5-15)22(23,24)25;1-3-28-14-15(2)26-22-25-12-20(29-22)18-10-19(21-24-8-9-27(21)13-18)17-6-4-16(11-23)5-7-17;1-3-13(2)27-20-26-11-18(29-20)15-10-17(19-25-8-9-28(19)12-15)14-4-6-16(7-5-14)21(22,23)24/h4-12,14H,3,13H2,1-2H3,(H,27,28);4-10,12-13,15H,3,11,14,23H2,1-2H3,(H,25,26);4-13H,3H2,1-2H3,(H,26,27)/t;;13-/m..1/s1
• InChIKey: UGAITCQQNUMPMU-QULCKEJLSA-N
• XLogP: 16.75
• TPSA: 171.14 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 18
• Rotatable Bonds: 20
• Heavy Atoms: 89
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1270.51
LogP ≤ 5	16.75
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	18

Frequently Asked Questions

What is the IUPAC name of 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine?

The IUPAC name of 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine (CID 161081937) is 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine.

What is the SMILES notation for 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine?

The canonical SMILES for 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine is CCOCC(C)Nc1ncc(-c2cc(-c3ccc(C(F)(F)F)cc3)c3nccn3c2)s1.CCOCC(C)Nc1ncc(-c2cc(-c3ccc(CN)cc3)c3nccn3c2)s1.CC[C@@H](C)Nc1ncc(-c2cc(-c3ccc(C(F)(F)F)cc3)c3nccn3c2)s1.

What is the InChIKey of 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine?

The InChIKey is UGAITCQQNUMPMU-QULCKEJLSA-N. The full InChI is InChI=1S/C22H21F3N4OS.C22H25N5OS.C21H19F3N4S/c1-3-30-13-14(2)28-21-27-11-19(31-21)16-10-18(20-26-8-9-29(20)12-16)15-4-6-17(7-5-15)22(23,24)25;1-3-28-14-15(2)26-22-25-12-20(29-22)18-10-19(21-24-8-9-27(21)13-18)17-6-4-16(11-23)5-7-17;1-3-13(2)27-20-26-11-18(29-20)15-10-17(19-25-8-9-28(19)12-15)14-4-6-16(7-5-14)21(22,23)24/h4-12,14H,3,13H2,1-2H3,(H,27,28);4-10,12-13,15H,3,11,14,23H2,1-2H3,(H,25,26);4-13H,3H2,1-2H3,(H,26,27)/t;;13-/m..1/s1.

What are the key properties of 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine?

5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine has a molecular weight of 1270.51 g/mol, XLogP of 16.75, 20 rotatable bonds, 4 hydrogen bond donors, and 18 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[8-[4-(aminomethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-N-(1-ethoxypropan-2-yl)-1,3-thiazol-2-amine;N-[(2R)-butan-2-yl]-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine;N-(1-ethoxypropan-2-yl)-5-[8-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]-1,3-thiazol-2-amine is sourced from PubChem (CID 161081937), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).