6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine

C144H179F14N23O2 — CID 158135751

About 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine

6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine (PubChem CID 158135751) has the molecular formula C144H179F14N23O2 and a molecular weight of 2530.15 g/mol. Its IUPAC name is 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine.

Molecular Properties

• Compound Name: 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine
• PubChem CID: 158135751
• Molecular Formula: C144H179F14N23O2
• Molecular Weight: 2530.15 g/mol
• Exact Mass: 2528.44
• IUPAC Name: 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine
• SMILES: CC(C)N1CCCc2cc(-c3cnn(C)c3)ncc21.CC(C)N1CC[C@@H](C)c2cc(-c3cnn(C)c3)c(C(F)F)cc21.CC(C)N1CC[C@H](C)c2cc(-c3cnn(C)c3)c(C(F)F)cc21.CC(C)N1C[C@@H](C)Cc2cc(-c3cnn(C)c3)c(C(F)F)cc21.CC(C)N1C[C@H](C)Cc2cc(-c3cnn(C)c3)c(C(F)F)cc21.CCC(=O)c1ccc(-c2cc3c(cc2C(F)F)N(C(C)C)CCC3)cn1.COc1cc(-c2cc3c(cc2C(F)F)N(C(C)C)CCC3)ccn1.Cc1c(-c2cc3c(cc2C(F)F)N(C(C)C)CC3)cnn1C
• InChI: InChI=1S/C21H24F2N2O.C19H22F2N2O.4C18H23F2N3.C17H21F2N3.C15H20N4/c1-4-20(26)18-8-7-15(12-24-18)16-10-14-6-5-9-25(13(2)3)19(14)11-17(16)21(22)23;1-12(2)23-8-4-5-14-9-15(16(19(20)21)11-17(14)23)13-6-7-22-18(10-13)24-3;2*1-11(2)23-9-12(3)5-13-6-15(14-8-21-22(4)10-14)16(18(19)20)7-17(13)23;2*1-11(2)23-6-5-12(3)14-7-15(13-9-21-22(4)10-13)16(18(19)20)8-17(14)23;1-10(2)22-6-5-12-7-13(14(17(18)19)8-16(12)22)15-9-20-21(4)11(15)3;1-11(2)19-6-4-5-12-7-14(16-9-15(12)19)13-8-17-18(3)10-13/h7-8,10-13,21H,4-6,9H2,1-3H3;6-7,9-12,19H,4-5,8H2,1-3H3;2*6-8,10-12,18H,5,9H2,1-4H3;2*7-12,18H,5-6H2,1-4H3;7-10,17H,5-6H2,1-4H3;7-11H,4-6H2,1-3H3/t;;4*12-;;/m..1010../s1
• InChIKey: FTIBTPMSHVRAHD-XZBQGCCWSA-N
• XLogP: 35.40
• TPSA: 197.81 Ų
• H-Bond Acceptors: 25
• Rotatable Bonds: 26
• Heavy Atoms: 183
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2530.15
LogP ≤ 5	35.40
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine?

The IUPAC name of 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine (CID 158135751) is 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine.

What is the SMILES notation for 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine?

The canonical SMILES for 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine is CC(C)N1CCCc2cc(-c3cnn(C)c3)ncc21.CC(C)N1CC[C@@H](C)c2cc(-c3cnn(C)c3)c(C(F)F)cc21.CC(C)N1CC[C@H](C)c2cc(-c3cnn(C)c3)c(C(F)F)cc21.CC(C)N1C[C@@H](C)Cc2cc(-c3cnn(C)c3)c(C(F)F)cc21.CC(C)N1C[C@H](C)Cc2cc(-c3cnn(C)c3)c(C(F)F)cc21.CCC(=O)c1ccc(-c2cc3c(cc2C(F)F)N(C(C)C)CCC3)cn1.COc1cc(-c2cc3c(cc2C(F)F)N(C(C)C)CCC3)ccn1.Cc1c(-c2cc3c(cc2C(F)F)N(C(C)C)CC3)cnn1C.

What is the InChIKey of 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine?

The InChIKey is FTIBTPMSHVRAHD-XZBQGCCWSA-N. The full InChI is InChI=1S/C21H24F2N2O.C19H22F2N2O.4C18H23F2N3.C17H21F2N3.C15H20N4/c1-4-20(26)18-8-7-15(12-24-18)16-10-14-6-5-9-25(13(2)3)19(14)11-17(16)21(22)23;1-12(2)23-8-4-5-14-9-15(16(19(20)21)11-17(14)23)13-6-7-22-18(10-13)24-3;2*1-11(2)23-9-12(3)5-13-6-15(14-8-21-22(4)10-14)16(18(19)20)7-17(13)23;2*1-11(2)23-6-5-12(3)14-7-15(13-9-21-22(4)10-13)16(18(19)20)8-17(14)23;1-10(2)22-6-5-12-7-13(14(17(18)19)8-16(12)22)15-9-20-21(4)11(15)3;1-11(2)19-6-4-5-12-7-14(16-9-15(12)19)13-8-17-18(3)10-13/h7-8,10-13,21H,4-6,9H2,1-3H3;6-7,9-12,19H,4-5,8H2,1-3H3;2*6-8,10-12,18H,5,9H2,1-4H3;2*7-12,18H,5-6H2,1-4H3;7-10,17H,5-6H2,1-4H3;7-11H,4-6H2,1-3H3/t;;4*12-;;/m..1010../s1.

What are the key properties of 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine?

6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine has a molecular weight of 2530.15 g/mol, XLogP of 35.40, 26 rotatable bonds, 0 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(difluoromethyl)-5-(1,5-dimethylpyrazol-4-yl)-1-propan-2-yl-2,3-dihydroindole;7-(difluoromethyl)-6-(2-methoxy-4-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3R)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(3S)-7-(difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4S)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;(4R)-7-(difluoromethyl)-4-methyl-6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;1-[5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-2-pyridinyl]propan-1-one;6-(1-methylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-1,7-naphthyridine is sourced from PubChem (CID 158135751), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).