N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide

C174H171F14N29O26S — CID 158172241

IUPACN-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide
SMILESCC(C)(C#N)c1cc(C(=O)NC2=CCC(=O)C(c3ccnc(N4CCOCC4)c3)=C2)ccn1.Cc1cc(=O)c(C(=O)Cc2cccc(C(F)(F)F)c2)cn1-c1ccnc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cc(C(=O)N2CC(O)C2)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(OCC2(N)COC2)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cnc(OC[C@@H](C)O)c(N2CCOCC2)c1.O=C1CC=C(NC(=O)c2cccc(C(F)F)c2)C=C1c1ccnc(N2CCOCC2)c1.O=C1CC=C(NC(=O)c2ccnc(C(F)(F)F)c2)C=C1c1ccnc(N2CCOCC2)c1
InChIInChI=1S/C27H28F3N5O4.C27H26F3N5O4.C26H30N4O6S.C25H25N5O3.C24H22F3N3O3.C23H21F2N3O3.C22H19F3N4O3/c1-17-2-3-20(33-25(36)18-4-5-32-22(10-18)27(28,29)30)13-21(17)19-11-23(35-6-8-37-9-7-35)34-24(12-19)39-16-26(31)14-38-15-26;1-16-2-3-19(32-25(37)22-12-18(4-5-31-22)27(28,29)30)13-21(16)17-10-23(26(38)35-14-20(36)15-35)33-24(11-17)34-6-8-39-9-7-34;1-17-4-5-21(29-25(32)19-6-7-27-24(13-19)37(3,33)34)14-22(17)20-12-23(30-8-10-35-11-9-30)26(28-15-20)36-16-18(2)31;1-25(2,16-26)22-13-18(6-7-27-22)24(32)29-19-3-4-21(31)20(15-19)17-5-8-28-23(14-17)30-9-11-33-12-10-30;1-16-11-21(31)20(22(32)13-17-3-2-4-18(12-17)24(25,26)27)15-30(16)19-5-6-28-23(14-19)29-7-9-33-10-8-29;24-22(25)16-2-1-3-17(12-16)23(30)27-18-4-5-20(29)19(14-18)15-6-7-26-21(13-15)28-8-10-31-11-9-28;23-22(24,25)19-11-15(4-5-26-19)21(31)28-16-1-2-18(30)17(13-16)14-3-6-27-20(12-14)29-7-9-32-10-8-29/h2-5,10-13H,6-9,14-16,31H2,1H3,(H,33,36);2-5,10-13,20,36H,6-9,14-15H2,1H3,(H,32,37);4-7,12-15,18,31H,8-11,16H2,1-3H3,(H,29,32);3,5-8,13-15H,4,9-12H2,1-2H3,(H,29,32);2-6,11-12,14-15H,7-10,13H2,1H3;1-4,6-7,12-14,22H,5,8-11H2,(H,27,30);1,3-6,11-13H,2,7-10H2,(H,28,31)/t;;18-;;;;/m..1..../s1
InChIKeyFXPBPKMMKDXUHP-VXSHBMHISA-N
MW3382.50 g/mol
LogP22.88
Rot. Bonds39

About N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide

N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide (PubChem CID 158172241) has the molecular formula C174H171F14N29O26S and a molecular weight of 3382.50 g/mol. Its IUPAC name is N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide.

Molecular Properties

Compound NameN-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide
PubChem CID158172241
Molecular FormulaC174H171F14N29O26S
Molecular Weight3382.50 g/mol
Exact Mass3380.24
IUPAC NameN-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide
SMILESCC(C)(C#N)c1cc(C(=O)NC2=CCC(=O)C(c3ccnc(N4CCOCC4)c3)=C2)ccn1.Cc1cc(=O)c(C(=O)Cc2cccc(C(F)(F)F)c2)cn1-c1ccnc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cc(C(=O)N2CC(O)C2)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(OCC2(N)COC2)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cnc(OC[C@@H](C)O)c(N2CCOCC2)c1.O=C1CC=C(NC(=O)c2cccc(C(F)F)c2)C=C1c1ccnc(N2CCOCC2)c1.O=C1CC=C(NC(=O)c2ccnc(C(F)(F)F)c2)C=C1c1ccnc(N2CCOCC2)c1
InChIInChI=1S/C27H28F3N5O4.C27H26F3N5O4.C26H30N4O6S.C25H25N5O3.C24H22F3N3O3.C23H21F2N3O3.C22H19F3N4O3/c1-17-2-3-20(33-25(36)18-4-5-32-22(10-18)27(28,29)30)13-21(17)19-11-23(35-6-8-37-9-7-35)34-24(12-19)39-16-26(31)14-38-15-26;1-16-2-3-19(32-25(37)22-12-18(4-5-31-22)27(28,29)30)13-21(16)17-10-23(26(38)35-14-20(36)15-35)33-24(11-17)34-6-8-39-9-7-34;1-17-4-5-21(29-25(32)19-6-7-27-24(13-19)37(3,33)34)14-22(17)20-12-23(30-8-10-35-11-9-30)26(28-15-20)36-16-18(2)31;1-25(2,16-26)22-13-18(6-7-27-22)24(32)29-19-3-4-21(31)20(15-19)17-5-8-28-23(14-17)30-9-11-33-12-10-30;1-16-11-21(31)20(22(32)13-17-3-2-4-18(12-17)24(25,26)27)15-30(16)19-5-6-28-23(14-19)29-7-9-33-10-8-29;24-22(25)16-2-1-3-17(12-16)23(30)27-18-4-5-20(29)19(14-18)15-6-7-26-21(13-15)28-8-10-31-11-9-28;23-22(24,25)19-11-15(4-5-26-19)21(31)28-16-1-2-18(30)17(13-16)14-3-6-27-20(12-14)29-7-9-32-10-8-29/h2-5,10-13H,6-9,14-16,31H2,1H3,(H,33,36);2-5,10-13,20,36H,6-9,14-15H2,1H3,(H,32,37);4-7,12-15,18,31H,8-11,16H2,1-3H3,(H,29,32);3,5-8,13-15H,4,9-12H2,1-2H3,(H,29,32);2-6,11-12,14-15H,7-10,13H2,1H3;1-4,6-7,12-14,22H,5,8-11H2,(H,27,30);1,3-6,11-13H,2,7-10H2,(H,28,31)/t;;18-;;;;/m..1..../s1
InChIKeyFXPBPKMMKDXUHP-VXSHBMHISA-N
XLogP22.88
TPSA679.26 Ų
H-Bond Donors9
H-Bond Acceptors48
Rotatable Bonds39
Heavy Atoms244
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003382.50
LogP ≤ 522.88
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1048

Analyze N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

N-[5-[6-(azetidin-3-yloxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-(2-cyanopropan-2-yl)-N-[5-(1-ethyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[5-[6-(2-cyanopropan-2-yl)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-(1-ethyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;4-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-3-(trifluoromethyl)benzamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[6-(methylsulfonylmethyl)-5-morpholin-4-yl-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157502605
N-[5-[6-(1-acetylpiperidin-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-[3-(difluoromethoxy)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;1-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-[3-(trifluoromethyl)phenyl]ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone;N-[4-methyl-3-[2-morpholin-4-yl-6-(2-pyrrolidin-1-ylethoxy)-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157562317
2-(2-cyanopropan-2-yl)-N-[3-[6-[[(2R)-2-hydroxypropyl]amino]-2-morpholin-4-ylpyrimidin-4-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-[6-[[(2R)-2-hydroxypropyl]amino]-2-morpholin-4-ylpyrimidin-4-yl]-4-methylphenyl]pyridine-4-carboxamide;N-[5-(5-ethoxy-6-morpholin-4-yl-2-pyridinyl)-6-methyl-3-pyridinyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[3-[6-[[(2R)-2-hydroxypropyl]amino]-2-morpholin-4-ylpyrimidin-4-yl]-4-methylphenyl]pyridine-4-carboxamide;N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-[6-[[(2R)-2-hydroxypropyl]amino]-2-morpholin-4-ylpyrimidin-4-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 158114370
N-[5-[5-cyano-6-(1,1-dioxo-1,4-thiazinan-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(3-hydroxyazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-(5-cyano-6-methoxy-3-pyridinyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(propylamino)-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
CID 158356876
N-[5-[6-(azetidin-3-yloxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-[6-(2-cyanopropan-2-yl)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-(1-ethyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;4-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-3-(trifluoromethyl)benzamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[6-(methylsulfonylmethyl)-5-morpholin-4-yl-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 158498722
N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 158859789
2-(2-cyanopropan-2-yl)-N-[3-[6-[[(2R)-2-hydroxypropyl]amino]-2-morpholin-4-ylpyrimidin-4-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(5-ethoxy-6-morpholin-4-yl-2-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[5-[6-(1,1-dioxothian-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(5-ethoxy-6-morpholin-4-yl-2-pyridinyl)-6-methyl-3-pyridinyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[5-[6-[2-(2-hydroxyethoxy)ethoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(trideuteriomethoxy)-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 159048832
N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 159284294
2-(2-cyanopropan-2-yl)-N-[5-[3-(3-fluorooxetan-3-yl)-5-(3-hydroxyoxetan-3-yl)phenyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-[3-(3-fluorooxetan-3-yl)-5-(3-hydroxyoxetan-3-yl)phenyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-[2-(2-hydroxyethoxy)-6-(3-methoxyoxetan-3-yl)-4-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-[5-(3-hydroxyoxetan-3-yl)-6-(1-methylpyrazol-4-yl)-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[5-[6-ethoxy-5-[3-(fluoromethyl)oxetan-3-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[5-[3-(3-fluorooxetan-3-yl)-5-(3-hydroxyoxetan-3-yl)phenyl]-6-methyl-3-pyridinyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;1-[3-[5-(3-hydroxyoxetan-3-yl)-6-methoxy-3-pyridinyl]-4-methylphenyl]-2-(2-methylsulfonyl-4-pyridinyl)ethanone
CID 159306868
2-(1,1-difluoroethyl)-N-[5-(5-ethoxy-6-morpholin-4-ylpyrazin-2-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[5-(5-ethoxy-6-morpholin-4-ylpyrazin-2-yl)-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;N-[5-(5-ethoxy-6-morpholin-4-ylpyrazin-2-yl)-6-methyl-3-pyridinyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[5-(5-ethoxy-6-morpholin-4-ylpyrazin-2-yl)-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-(5-methoxy-6-morpholin-4-ylpyrazin-2-yl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 159487682
2-(1,1-difluoroethyl)-N-[5-(5-ethoxy-6-morpholin-4-yl-2-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-[2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[3-[2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]benzamide;N-[5-[6-(1,1-dioxothian-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-[6-[2-(2-hydroxyethoxy)ethoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(trideuteriomethoxy)-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 159557691
2-(1,1-difluoroethyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]benzamide;2-(1,1-difluoropropyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-3-methylsulfonylbenzamide;N-[5-[6-[(3S,4S)-3-methoxyoxan-4-yl]oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[2-morpholin-4-yl-6-(oxan-4-yloxy)-4-pyridinyl]phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;1-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-2-[3-(trifluoromethyl)phenyl]ethanone
CID 159801934

Frequently Asked Questions

What is the IUPAC name of N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The IUPAC name of N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide (CID 158172241) is N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide.
What is the SMILES notation for N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The canonical SMILES for N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide is CC(C)(C#N)c1cc(C(=O)NC2=CCC(=O)C(c3ccnc(N4CCOCC4)c3)=C2)ccn1.Cc1cc(=O)c(C(=O)Cc2cccc(C(F)(F)F)c2)cn1-c1ccnc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2cc(C(F)(F)F)ccn2)cc1-c1cc(C(=O)N2CC(O)C2)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(OCC2(N)COC2)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cnc(OC[C@@H](C)O)c(N2CCOCC2)c1.O=C1CC=C(NC(=O)c2cccc(C(F)F)c2)C=C1c1ccnc(N2CCOCC2)c1.O=C1CC=C(NC(=O)c2ccnc(C(F)(F)F)c2)C=C1c1ccnc(N2CCOCC2)c1.
What is the InChIKey of N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide?
The InChIKey is FXPBPKMMKDXUHP-VXSHBMHISA-N. The full InChI is InChI=1S/C27H28F3N5O4.C27H26F3N5O4.C26H30N4O6S.C25H25N5O3.C24H22F3N3O3.C23H21F2N3O3.C22H19F3N4O3/c1-17-2-3-20(33-25(36)18-4-5-32-22(10-18)27(28,29)30)13-21(17)19-11-23(35-6-8-37-9-7-35)34-24(12-19)39-16-26(31)14-38-15-26;1-16-2-3-19(32-25(37)22-12-18(4-5-31-22)27(28,29)30)13-21(16)17-10-23(26(38)35-14-20(36)15-35)33-24(11-17)34-6-8-39-9-7-34;1-17-4-5-21(29-25(32)19-6-7-27-24(13-19)37(3,33)34)14-22(17)20-12-23(30-8-10-35-11-9-30)26(28-15-20)36-16-18(2)31;1-25(2,16-26)22-13-18(6-7-27-22)24(32)29-19-3-4-21(31)20(15-19)17-5-8-28-23(14-17)30-9-11-33-12-10-30;1-16-11-21(31)20(22(32)13-17-3-2-4-18(12-17)24(25,26)27)15-30(16)19-5-6-28-23(14-19)29-7-9-33-10-8-29;24-22(25)16-2-1-3-17(12-16)23(30)27-18-4-5-20(29)19(14-18)15-6-7-26-21(13-15)28-8-10-31-11-9-28;23-22(24,25)19-11-15(4-5-26-19)21(31)28-16-1-2-18(30)17(13-16)14-3-6-27-20(12-14)29-7-9-32-10-8-29/h2-5,10-13H,6-9,14-16,31H2,1H3,(H,33,36);2-5,10-13,20,36H,6-9,14-15H2,1H3,(H,32,37);4-7,12-15,18,31H,8-11,16H2,1-3H3,(H,29,32);3,5-8,13-15H,4,9-12H2,1-2H3,(H,29,32);2-6,11-12,14-15H,7-10,13H2,1H3;1-4,6-7,12-14,22H,5,8-11H2,(H,27,30);1,3-6,11-13H,2,7-10H2,(H,28,31)/t;;18-;;;;/m..1..../s1.
What are the key properties of N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide?
N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide has a molecular weight of 3382.50 g/mol, XLogP of 22.88, 39 rotatable bonds, 9 hydrogen bond donors, and 48 hydrogen bond acceptors.
Where does this data come from?
All data for N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide is sourced from PubChem (CID 158172241), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).