N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide

C158H171F11N26O24S — CID 158859789

IUPACN-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide
SMILESCNC(=O)c1ncc(-c2cc(NC(=O)c3cccc(C(C)(C)F)c3)cnc2C)cc1N1CCOCC1.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(NC[C@@H](C)O)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cnc(OC[C@H](C)O)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cnc(OCC2COCCO2)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1C1=CCC(=O)C(N2CCOCC2)=C1.Cc1ncc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cnc(OC[C@H](C)O)c(N2CCOCC2)c1
InChIInChI=1S/C28H29F3N4O5.C27H32FN5O4.C27H30FN5O3.C26H28F3N5O3.C26H30N4O6S.C24H22F3N3O3/c1-18-24(13-22(15-32-18)34-26(36)19-3-2-4-21(11-19)28(29,30)31)20-12-25(35-5-7-37-8-6-35)27(33-14-20)40-17-23-16-38-9-10-39-23;1-17(34)16-37-26-23(33-7-9-36-10-8-33)11-20(14-31-26)22-13-21(15-30-18(22)2)32-25(35)19-5-6-29-24(12-19)27(3,4)28;1-17-22(19-13-23(33-8-10-36-11-9-33)24(31-15-19)26(35)29-4)14-21(16-30-17)32-25(34)18-6-5-7-20(12-18)27(2,3)28;1-16-3-4-20(32-25(36)18-5-6-30-22(11-18)26(27,28)29)14-21(16)19-12-23(31-15-17(2)35)33-24(13-19)34-7-9-37-10-8-34;1-17-4-5-21(29-25(32)19-6-7-27-24(13-19)37(3,33)34)14-22(17)20-12-23(30-8-10-35-11-9-30)26(28-15-20)36-16-18(2)31;1-15-20(16-5-6-22(31)21(12-16)30-7-9-33-10-8-30)13-19(14-28-15)29-23(32)17-3-2-4-18(11-17)24(25,26)27/h2-4,11-15,23H,5-10,16-17H2,1H3,(H,34,36);5-6,11-15,17,34H,7-10,16H2,1-4H3,(H,32,35);5-7,12-16H,8-11H2,1-4H3,(H,29,35)(H,32,34);3-6,11-14,17,35H,7-10,15H2,1-2H3,(H,31,33)(H,32,36);4-7,12-15,18,31H,8-11,16H2,1-3H3,(H,29,32);2-5,11-14H,6-10H2,1H3,(H,29,32)/t;17-;;17-;18-;/m.0.10./s1
InChIKeyJAMZMDRWEOENGA-LEEGGBIZSA-N
MW3059.31 g/mol
LogP23.65
Rot. Bonds40

About N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide

N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide (PubChem CID 158859789) has the molecular formula C158H171F11N26O24S and a molecular weight of 3059.31 g/mol. Its IUPAC name is N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide.

Molecular Properties

Compound NameN-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide
PubChem CID158859789
Molecular FormulaC158H171F11N26O24S
Molecular Weight3059.31 g/mol
Exact Mass3057.25
IUPAC NameN-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide
SMILESCNC(=O)c1ncc(-c2cc(NC(=O)c3cccc(C(C)(C)F)c3)cnc2C)cc1N1CCOCC1.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(NC[C@@H](C)O)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cnc(OC[C@H](C)O)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cnc(OCC2COCCO2)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1C1=CCC(=O)C(N2CCOCC2)=C1.Cc1ncc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cnc(OC[C@H](C)O)c(N2CCOCC2)c1
InChIInChI=1S/C28H29F3N4O5.C27H32FN5O4.C27H30FN5O3.C26H28F3N5O3.C26H30N4O6S.C24H22F3N3O3/c1-18-24(13-22(15-32-18)34-26(36)19-3-2-4-21(11-19)28(29,30)31)20-12-25(35-5-7-37-8-6-35)27(33-14-20)40-17-23-16-38-9-10-39-23;1-17(34)16-37-26-23(33-7-9-36-10-8-33)11-20(14-31-26)22-13-21(15-30-18(22)2)32-25(35)19-5-6-29-24(12-19)27(3,4)28;1-17-22(19-13-23(33-8-10-36-11-9-33)24(31-15-19)26(35)29-4)14-21(16-30-17)32-25(34)18-6-5-7-20(12-18)27(2,3)28;1-16-3-4-20(32-25(36)18-5-6-30-22(11-18)26(27,28)29)14-21(16)19-12-23(31-15-17(2)35)33-24(13-19)34-7-9-37-10-8-34;1-17-4-5-21(29-25(32)19-6-7-27-24(13-19)37(3,33)34)14-22(17)20-12-23(30-8-10-35-11-9-30)26(28-15-20)36-16-18(2)31;1-15-20(16-5-6-22(31)21(12-16)30-7-9-33-10-8-30)13-19(14-28-15)29-23(32)17-3-2-4-18(11-17)24(25,26)27/h2-4,11-15,23H,5-10,16-17H2,1H3,(H,34,36);5-6,11-15,17,34H,7-10,16H2,1-4H3,(H,32,35);5-7,12-16H,8-11H2,1-4H3,(H,29,35)(H,32,34);3-6,11-14,17,35H,7-10,15H2,1-2H3,(H,31,33)(H,32,36);4-7,12-15,18,31H,8-11,16H2,1-3H3,(H,29,32);2-5,11-14H,6-10H2,1H3,(H,29,32)/t;17-;;17-;18-;/m.0.10./s1
InChIKeyJAMZMDRWEOENGA-LEEGGBIZSA-N
XLogP23.65
TPSA603.28 Ų
H-Bond Donors11
H-Bond Acceptors43
Rotatable Bonds40
Heavy Atoms220
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003059.31
LogP ≤ 523.65
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1043

Analyze N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide with MolForge

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Launch Full Analysis

Related Compounds

N-[5-[6-(1-acetylpiperidin-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-[3-(difluoromethoxy)phenyl]-1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]ethanone;1-[5-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-2-[3-(trifluoromethyl)phenyl]ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-(3-methylsulfonylphenyl)ethanone;1-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxy-3-pyridinyl)-3-pyridinyl]-2-[3-(trifluoromethoxy)phenyl]ethanone;N-[4-methyl-3-[2-morpholin-4-yl-6-(2-pyrrolidin-1-ylethoxy)-4-pyridinyl]phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157562317
N-[2-fluoro-5-[2-(2-hydroxyethoxy)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-[2-(2-hydroxyethoxy)-6-morpholin-4-yl-4-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-[2-[(2S)-1-hydroxypropan-2-yl]oxy-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157591436
N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]benzamide;N-[3-[2-(3-hydroxyazetidine-1-carbonyl)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 158172241
N-[5-[5-cyano-6-(1,1-dioxo-1,4-thiazinan-4-yl)-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(3-hydroxyazetidin-1-yl)-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-(5-cyano-6-methoxy-3-pyridinyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-(5-cyano-6-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(oxan-4-ylamino)-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[5-cyano-6-(propylamino)-3-pyridinyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
CID 158356876
1-ethyl-N-[5-[2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-6-methyl-3-pyridinyl]-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;3-(4-ethylpiperazin-1-yl)-N-[5-[2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;N-[5-[2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-6-methyl-3-pyridinyl]-3-(2-hydroxypropan-2-yl)benzamide;N-[5-[2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-6-methyl-3-pyridinyl]-2-methylsulfonylpyridine-4-carboxamide
CID 158480797
N-[5-[6-(4-deuteriooxan-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;3-(1,1-difluoro-2-hydroxyethyl)-N-[4-methyl-3-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-[2-morpholin-4-yl-6-(oxan-4-yloxy)-4-pyridinyl]phenyl]pyridine-4-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-[2-morpholin-4-yl-6-(oxan-4-yloxy)-4-pyridinyl]phenyl]pyridine-4-carboxamide
CID 158776131
2-(2-cyanopropan-2-yl)-N-[3-[6-[[(2R)-2-hydroxypropyl]amino]-2-morpholin-4-ylpyrimidin-4-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(5-ethoxy-6-morpholin-4-yl-2-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[5-[6-(1,1-dioxothian-4-yl)oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(5-ethoxy-6-morpholin-4-yl-2-pyridinyl)-6-methyl-3-pyridinyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[5-[6-[2-(2-hydroxyethoxy)ethoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(trideuteriomethoxy)-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 159048832
N-[3-[2-[(3-aminooxetan-3-yl)methoxy]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]pyridine-4-carboxamide;N-[3-[6-[(2R)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;2-methyl-1-(2-morpholin-4-yl-4-pyridinyl)-5-[2-[3-(trifluoromethyl)phenyl]acetyl]pyridin-4-one;N-[5-(2-morpholin-4-yl-4-pyridinyl)-4-oxocyclohexa-1,5-dien-1-yl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 159284294
2-[2-(1,1-difluoroethyl)-4-pyridinyl]-1-[3-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]ethanone;N-[3-[3,5-difluoro-2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[3-[3,5-difluoro-2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(difluoromethyl)-N-[3-[3-fluoro-2-(2-hydroxyethylamino)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[5-[6-[(2R)-1-hydroxypropan-2-yl]oxy-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;1-[3-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-[2-(trifluoromethyl)-4-pyridinyl]ethanone
CID 159467237
N-cyclopropyl-1-[3-(6-methoxy-3-pyridinyl)phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide;N-cyclopropyl-1-[3-(6-methyl-3-pyridinyl)phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide;N-cyclopropyl-1-[3-(6-methylsulfonyl-3-pyridinyl)phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide;N-cyclopropyl-4-oxo-1-[3-[6-(2,2,2-trifluoroethoxy)-3-pyridinyl]phenyl]-1,8-naphthyridine-3-carboxamide
CID 159469047
2-(1,1-difluoroethyl)-N-[5-(5-ethoxy-6-morpholin-4-ylpyrazin-2-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;3-[(dimethylamino)methyl]-N-[5-(5-ethoxy-6-morpholin-4-ylpyrazin-2-yl)-6-methyl-3-pyridinyl]-5-(trifluoromethyl)benzamide;N-[5-(5-ethoxy-6-morpholin-4-ylpyrazin-2-yl)-6-methyl-3-pyridinyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[5-(5-ethoxy-6-morpholin-4-ylpyrazin-2-yl)-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-(5-methoxy-6-morpholin-4-ylpyrazin-2-yl)-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 159487682
2-cyclopropyl-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]pyridine-4-carboxamide;N-[5-[3-fluoro-6-(2-hydroxyethylamino)-2-morpholin-4-yl-4-pyridinyl]-6-methyl-3-pyridinyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[3-[6-(2-hydroxyethoxy)-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-5-(trifluoromethyl)pyridine-3-carboxamide;methyl N-[(2R)-2-[[5-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]-3-pyridinyl]-3-morpholin-4-yl-2-pyridinyl]oxy]propyl]carbamate
CID 159557122

Frequently Asked Questions

What is the IUPAC name of N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide?
The IUPAC name of N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide (CID 158859789) is N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide.
What is the SMILES notation for N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide?
The canonical SMILES for N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide is CNC(=O)c1ncc(-c2cc(NC(=O)c3cccc(C(C)(C)F)c3)cnc2C)cc1N1CCOCC1.Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(NC[C@@H](C)O)nc(N2CCOCC2)c1.Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1cnc(OC[C@H](C)O)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cnc(OCC2COCCO2)c(N2CCOCC2)c1.Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1C1=CCC(=O)C(N2CCOCC2)=C1.Cc1ncc(NC(=O)c2ccnc(C(C)(C)F)c2)cc1-c1cnc(OC[C@H](C)O)c(N2CCOCC2)c1.
What is the InChIKey of N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide?
The InChIKey is JAMZMDRWEOENGA-LEEGGBIZSA-N. The full InChI is InChI=1S/C28H29F3N4O5.C27H32FN5O4.C27H30FN5O3.C26H28F3N5O3.C26H30N4O6S.C24H22F3N3O3/c1-18-24(13-22(15-32-18)34-26(36)19-3-2-4-21(11-19)28(29,30)31)20-12-25(35-5-7-37-8-6-35)27(33-14-20)40-17-23-16-38-9-10-39-23;1-17(34)16-37-26-23(33-7-9-36-10-8-33)11-20(14-31-26)22-13-21(15-30-18(22)2)32-25(35)19-5-6-29-24(12-19)27(3,4)28;1-17-22(19-13-23(33-8-10-36-11-9-33)24(31-15-19)26(35)29-4)14-21(16-30-17)32-25(34)18-6-5-7-20(12-18)27(2,3)28;1-16-3-4-20(32-25(36)18-5-6-30-22(11-18)26(27,28)29)14-21(16)19-12-23(31-15-17(2)35)33-24(13-19)34-7-9-37-10-8-34;1-17-4-5-21(29-25(32)19-6-7-27-24(13-19)37(3,33)34)14-22(17)20-12-23(30-8-10-35-11-9-30)26(28-15-20)36-16-18(2)31;1-15-20(16-5-6-22(31)21(12-16)30-7-9-33-10-8-30)13-19(14-28-15)29-23(32)17-3-2-4-18(11-17)24(25,26)27/h2-4,11-15,23H,5-10,16-17H2,1H3,(H,34,36);5-6,11-15,17,34H,7-10,16H2,1-4H3,(H,32,35);5-7,12-16H,8-11H2,1-4H3,(H,29,35)(H,32,34);3-6,11-14,17,35H,7-10,15H2,1-2H3,(H,31,33)(H,32,36);4-7,12-15,18,31H,8-11,16H2,1-3H3,(H,29,32);2-5,11-14H,6-10H2,1H3,(H,29,32)/t;17-;;17-;18-;/m.0.10./s1.
What are the key properties of N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide?
N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide has a molecular weight of 3059.31 g/mol, XLogP of 23.65, 40 rotatable bonds, 11 hydrogen bond donors, and 43 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-[6-(1,4-dioxan-2-ylmethoxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;5-[5-[[3-(2-fluoropropan-2-yl)benzoyl]amino]-2-methyl-3-pyridinyl]-N-methyl-3-morpholin-4-ylpyridine-2-carboxamide;2-(2-fluoropropan-2-yl)-N-[5-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[3-[6-[(2S)-2-hydroxypropoxy]-5-morpholin-4-yl-3-pyridinyl]-4-methylphenyl]-2-methylsulfonylpyridine-4-carboxamide;N-[3-[2-[[(2R)-2-hydroxypropyl]amino]-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-(5-morpholin-4-yl-4-oxocyclohexa-1,5-dien-1-yl)-3-pyridinyl]-3-(trifluoromethyl)benzamide is sourced from PubChem (CID 158859789), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).