2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one

C126H98F16N34O6 — CID 158184762

About 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one

2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one (PubChem CID 158184762) has the molecular formula C126H98F16N34O6 and a molecular weight of 2488.37 g/mol. Its IUPAC name is 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one.

Molecular Properties

• Compound Name: 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one
• PubChem CID: 158184762
• Molecular Formula: C126H98F16N34O6
• Molecular Weight: 2488.37 g/mol
• Exact Mass: 2486.82
• IUPAC Name: 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one
• SMILES: CN1C(=O)C(c2ccc(C(C)(F)F)nc2)(c2cccc(-c3ccnnc3)c2)N=C1N.CN1C(=O)C(c2ccc(C(F)(F)F)nc2)(c2cccc(-c3cccnc3)c2)N=C1N.CN1C(=O)C(c2ccc(C(F)(F)F)nc2)(c2cccc(-c3cccnn3)c2)N=C1N.CN1C(=O)C(c2cccc(-c3ccccn3)c2)(c2ccc(C(C)(F)F)cn2)N=C1N.CN1C(=O)C(c2cccc(-c3cncc(C#N)c3)c2)(c2ccc(C(F)(F)F)cn2)N=C1N.CN1C(=O)C(c2cccc(-c3cnccn3)c2)(c2ccc(C(F)(F)F)cn2)N=C1N
• InChI: InChI=1S/C22H15F3N6O.C22H19F2N5O.C21H16F3N5O.C21H18F2N6O.2C20H15F3N6O/c1-31-19(32)21(30-20(31)27,18-6-5-17(12-29-18)22(23,24)25)16-4-2-3-14(8-16)15-7-13(9-26)10-28-11-15;1-21(23,24)16-9-10-18(27-13-16)22(19(30)29(2)20(25)28-22)15-7-5-6-14(12-15)17-8-3-4-11-26-17;1-29-18(30)20(28-19(29)25,16-7-8-17(27-12-16)21(22,23)24)15-6-2-4-13(10-15)14-5-3-9-26-11-14;1-20(22,23)17-7-6-16(12-25-17)21(18(30)29(2)19(24)28-21)15-5-3-4-13(10-15)14-8-9-26-27-11-14;1-29-17(30)19(27-18(29)24,14-7-8-16(25-11-14)20(21,22)23)13-5-2-4-12(10-13)15-6-3-9-26-28-15;1-29-17(30)19(28-18(29)24,16-6-5-14(10-27-16)20(21,22)23)13-4-2-3-12(9-13)15-11-25-7-8-26-15/h2-8,10-12H,1H3,(H2,27,30);3-13H,1-2H3,(H2,25,28);2-12H,1H3,(H2,25,28);3-12H,1-2H3,(H2,24,28);2-11H,1H3,(H2,24,27);2-11H,1H3,(H2,24,28)
• InChIKey: FYZYKGLMICKNHD-UHFFFAOYSA-N
• XLogP: 17.40
• TPSA: 569.28 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 34
• Rotatable Bonds: 20
• Heavy Atoms: 182
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2488.37
LogP ≤ 5	17.40
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one?

The IUPAC name of 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one (CID 158184762) is 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one.

What is the SMILES notation for 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one?

The canonical SMILES for 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one is CN1C(=O)C(c2ccc(C(C)(F)F)nc2)(c2cccc(-c3ccnnc3)c2)N=C1N.CN1C(=O)C(c2ccc(C(F)(F)F)nc2)(c2cccc(-c3cccnc3)c2)N=C1N.CN1C(=O)C(c2ccc(C(F)(F)F)nc2)(c2cccc(-c3cccnn3)c2)N=C1N.CN1C(=O)C(c2cccc(-c3ccccn3)c2)(c2ccc(C(C)(F)F)cn2)N=C1N.CN1C(=O)C(c2cccc(-c3cncc(C#N)c3)c2)(c2ccc(C(F)(F)F)cn2)N=C1N.CN1C(=O)C(c2cccc(-c3cnccn3)c2)(c2ccc(C(F)(F)F)cn2)N=C1N.

What is the InChIKey of 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one?

The InChIKey is FYZYKGLMICKNHD-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H15F3N6O.C22H19F2N5O.C21H16F3N5O.C21H18F2N6O.2C20H15F3N6O/c1-31-19(32)21(30-20(31)27,18-6-5-17(12-29-18)22(23,24)25)16-4-2-3-14(8-16)15-7-13(9-26)10-28-11-15;1-21(23,24)16-9-10-18(27-13-16)22(19(30)29(2)20(25)28-22)15-7-5-6-14(12-15)17-8-3-4-11-26-17;1-29-18(30)20(28-19(29)25,16-7-8-17(27-12-16)21(22,23)24)15-6-2-4-13(10-15)14-5-3-9-26-11-14;1-20(22,23)17-7-6-16(12-25-17)21(18(30)29(2)19(24)28-21)15-5-3-4-13(10-15)14-8-9-26-27-11-14;1-29-17(30)19(27-18(29)24,14-7-8-16(25-11-14)20(21,22)23)13-5-2-4-12(10-13)15-6-3-9-26-28-15;1-29-17(30)19(28-18(29)24,16-6-5-14(10-27-16)20(21,22)23)13-4-2-3-12(9-13)15-11-25-7-8-26-15/h2-8,10-12H,1H3,(H2,27,30);3-13H,1-2H3,(H2,25,28);2-12H,1H3,(H2,25,28);3-12H,1-2H3,(H2,24,28);2-11H,1H3,(H2,24,27);2-11H,1H3,(H2,24,28).

What are the key properties of 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one?

2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one has a molecular weight of 2488.37 g/mol, XLogP of 17.40, 20 rotatable bonds, 6 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for 2-amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one is sourced from PubChem (CID 158184762), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).