2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile

C126H87F26N33O6 — CID 158223717

IUPAC2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile
SMILESCN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cccnc3F)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cccnn3)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncc(C#N)c3)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncc(F)c3)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cnccn3)c2)N=C1N.Cc1ncccc1-c1cc(C2(c3cncc(C(F)(F)F)c3)N=C(N)N(C)C2=O)ccc1F
InChIInChI=1S/C22H14F4N6O.C22H17F4N5O.2C21H14F5N5O.2C20H14F4N6O/c1-32-19(33)21(31-20(32)28,15-5-16(11-30-10-15)22(24,25)26)14-2-3-18(23)17(6-14)13-4-12(7-27)8-29-9-13;1-12-16(4-3-7-29-12)17-9-13(5-6-18(17)23)21(19(32)31(2)20(27)30-21)14-8-15(11-28-10-14)22(24,25)26;1-31-18(32)20(30-19(31)27,13-5-14(9-29-8-13)21(24,25)26)12-2-3-17(23)16(6-12)11-4-15(22)10-28-7-11;1-31-18(32)20(30-19(31)27,12-7-13(10-28-9-12)21(24,25)26)11-4-5-16(22)15(8-11)14-3-2-6-29-17(14)23;1-30-17(31)19(29-18(30)25,12-6-13(9-27-8-12)20(22,23)24)11-2-3-15(21)14(7-11)16-10-26-4-5-28-16;1-30-17(31)19(28-18(30)25,12-7-13(10-26-9-12)20(22,23)24)11-4-5-15(21)14(8-11)16-3-2-6-27-29-16/h2-6,8-11H,1H3,(H2,28,31);3-11H,1-2H3,(H2,27,30);2*2-10H,1H3,(H2,27,30);2-10H,1H3,(H2,25,29);2-10H,1H3,(H2,25,28)
InChIKeyGDNZBLXSQAHTDF-UHFFFAOYSA-N
MW2653.25 g/mol
LogP19.24
Rot. Bonds18

About 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile

2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile (PubChem CID 158223717) has the molecular formula C126H87F26N33O6 and a molecular weight of 2653.25 g/mol. Its IUPAC name is 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile.

Molecular Properties

Compound Name2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile
PubChem CID158223717
Molecular FormulaC126H87F26N33O6
Molecular Weight2653.25 g/mol
Exact Mass2651.71
IUPAC Name2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile
SMILESCN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cccnc3F)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cccnn3)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncc(C#N)c3)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncc(F)c3)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cnccn3)c2)N=C1N.Cc1ncccc1-c1cc(C2(c3cncc(C(F)(F)F)c3)N=C(N)N(C)C2=O)ccc1F
InChIInChI=1S/C22H14F4N6O.C22H17F4N5O.2C21H14F5N5O.2C20H14F4N6O/c1-32-19(33)21(31-20(32)28,15-5-16(11-30-10-15)22(24,25)26)14-2-3-18(23)17(6-14)13-4-12(7-27)8-29-9-13;1-12-16(4-3-7-29-12)17-9-13(5-6-18(17)23)21(19(32)31(2)20(27)30-21)14-8-15(11-28-10-14)22(24,25)26;1-31-18(32)20(30-19(31)27,13-5-14(9-29-8-13)21(24,25)26)12-2-3-17(23)16(6-12)11-4-15(22)10-28-7-11;1-31-18(32)20(30-19(31)27,12-7-13(10-28-9-12)21(24,25)26)11-4-5-16(22)15(8-11)14-3-2-6-29-17(14)23;1-30-17(31)19(29-18(30)25,12-6-13(9-27-8-12)20(22,23)24)11-2-3-15(21)14(7-11)16-10-26-4-5-28-16;1-30-17(31)19(28-18(30)25,12-7-13(10-26-9-12)20(22,23)24)11-4-5-15(21)14(8-11)16-3-2-6-27-29-16/h2-6,8-11H,1H3,(H2,28,31);3-11H,1-2H3,(H2,27,30);2*2-10H,1H3,(H2,27,30);2-10H,1H3,(H2,25,29);2-10H,1H3,(H2,25,28)
InChIKeyGDNZBLXSQAHTDF-UHFFFAOYSA-N
XLogP19.24
TPSA556.39 Ų
H-Bond Donors6
H-Bond Acceptors33
Rotatable Bonds18
Heavy Atoms191
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002653.25
LogP ≤ 519.24
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1033

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Analyze 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-Amino-3-[[3-[2-amino-1-[[3-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-5-pyrimidin-5-ylphenyl]methyl]-4-[3-(difluoromethyl)phenyl]-5-oxoimidazol-4-yl]-5-pyrimidin-5-ylphenyl]methyl]-5-[6-(fluoromethyl)-3-pyridinyl]-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one
CID 142510293
2-Amino-5-[2-[2-[2-amino-4-[4-[2-[2-amino-4-(6-ethyl-3-pyridinyl)-5-oxo-4-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]imidazol-1-yl]-1-fluoroethyl]-2-pyridinyl]-5-oxo-4-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]imidazol-1-yl]-1-fluoroethyl]-4-pyridinyl]-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]imidazol-4-one
CID 146623003
2-Amino-5-(4-ethylphenyl)-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]imidazol-4-one;2-amino-5-[5-(fluoromethyl)-3-pyridinyl]-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]imidazol-4-one;2-amino-5-[6-(fluoromethyl)-2-pyridinyl]-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]imidazol-4-one;2-amino-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]-5-[4-(trifluoromethyl)phenyl]imidazol-4-one;2-amino-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one
CID 157050882
N-[6-(1-acetyl-3,6-dihydro-2H-pyridin-4-yl)-3-pyridinyl]-2-[4-(2-methyl-4-pyridinyl)phenyl]acetamide;2-[3-methyl-4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-piperidin-1-yl-3-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(5-pyridazin-4-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)phenyl]-N-(6-pyridazin-4-yl-3-pyridinyl)acetamide;2-(3-methyl-4-pyridin-4-ylphenyl)-N-(5-pyridin-2-yl-2-pyridinyl)acetamide;2-[4-(2-methyl-4-pyridinyl)-3-(trifluoromethyl)phenyl]-N-(5-pyrazin-2-yl-2-pyridinyl)acetamide
CID 157829070
2-Amino-5-[5-(difluoromethyl)-2-pyridinyl]-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]imidazol-4-one;2-amino-5-[5-(difluoromethyl)-3-pyridinyl]-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]imidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]imidazol-4-one;2-amino-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-[3-(5-prop-1-ynyl-3-pyridinyl)phenyl]-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one
CID 158132214
2-Amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-pyridazin-4-ylphenyl)imidazol-4-one;2-amino-5-[5-(1,1-difluoroethyl)-2-pyridinyl]-3-methyl-5-(3-pyridin-2-ylphenyl)imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]phenyl]pyridine-3-carbonitrile;2-amino-3-methyl-5-(3-pyrazin-2-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridazin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyridin-3-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one
CID 158184762
2-Amino-5-[2-fluoro-5-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-pyridazin-4-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-pyridin-2-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;5-[3-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-4-fluorophenyl]pyridine-3-carbonitrile
CID 158250509
CID 158439255
CID 158439255
CID 158825599
CID 158825599
tert-butyl 4-[5-[[2-[4-(2-methyl-4-pyridinyl)phenyl]acetyl]amino]-2-pyridinyl]piperazine-1-carboxylate;N-[6-(1-ethyl-3,6-dihydro-2H-pyridin-4-yl)-3-pyridinyl]-2-[4-(2-methyl-4-pyridinyl)phenyl]acetamide;N-[6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-3-pyridinyl]-2-[4-(2-methyl-4-pyridinyl)phenyl]acetamide;2-(2-methyl-4-pyridinyl)-5-[2-oxo-3-[5-(4-prop-1-en-2-ylpiperazin-1-yl)-2-pyridinyl]propyl]benzonitrile;N-(5-pyridazin-3-yl-2-pyridinyl)-2-(4-pyridin-4-ylphenyl)acetamide;bis(1-[4-pyridazin-4-yl-3-(trifluoromethyl)phenyl]-3-(5-pyridin-2-yl-2-pyridinyl)propan-2-one)
CID 159133024
2-Amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one
CID 160533477
CID 160818942
CID 160818942

Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile?
The IUPAC name of 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile (CID 158223717) is 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile.
What is the SMILES notation for 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile?
The canonical SMILES for 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile is CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cccnc3F)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cccnn3)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncc(C#N)c3)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncc(F)c3)c2)N=C1N.CN1C(=O)C(c2cncc(C(F)(F)F)c2)(c2ccc(F)c(-c3cnccn3)c2)N=C1N.Cc1ncccc1-c1cc(C2(c3cncc(C(F)(F)F)c3)N=C(N)N(C)C2=O)ccc1F.
What is the InChIKey of 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile?
The InChIKey is GDNZBLXSQAHTDF-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H14F4N6O.C22H17F4N5O.2C21H14F5N5O.2C20H14F4N6O/c1-32-19(33)21(31-20(32)28,15-5-16(11-30-10-15)22(24,25)26)14-2-3-18(23)17(6-14)13-4-12(7-27)8-29-9-13;1-12-16(4-3-7-29-12)17-9-13(5-6-18(17)23)21(19(32)31(2)20(27)30-21)14-8-15(11-28-10-14)22(24,25)26;1-31-18(32)20(30-19(31)27,13-5-14(9-29-8-13)21(24,25)26)12-2-3-17(23)16(6-12)11-4-15(22)10-28-7-11;1-31-18(32)20(30-19(31)27,12-7-13(10-28-9-12)21(24,25)26)11-4-5-16(22)15(8-11)14-3-2-6-29-17(14)23;1-30-17(31)19(29-18(30)25,12-6-13(9-27-8-12)20(22,23)24)11-2-3-15(21)14(7-11)16-10-26-4-5-28-16;1-30-17(31)19(28-18(30)25,12-7-13(10-26-9-12)20(22,23)24)11-4-5-15(21)14(8-11)16-3-2-6-27-29-16/h2-6,8-11H,1H3,(H2,28,31);3-11H,1-2H3,(H2,27,30);2*2-10H,1H3,(H2,27,30);2-10H,1H3,(H2,25,29);2-10H,1H3,(H2,25,28).
What are the key properties of 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile?
2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile has a molecular weight of 2653.25 g/mol, XLogP of 19.24, 18 rotatable bonds, 6 hydrogen bond donors, and 33 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-5-[4-fluoro-3-(2-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(5-fluoro-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methyl-3-pyridinyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyrazin-2-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-pyridazin-3-ylphenyl)-3-methyl-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;5-[5-[2-amino-1-methyl-5-oxo-4-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]-2-fluorophenyl]pyridine-3-carbonitrile is sourced from PubChem (CID 158223717), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).