4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one

C119H98Cl2N28O6S6 — CID 158187756

About 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one

4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one (PubChem CID 158187756) has the molecular formula C119H98Cl2N28O6S6 and a molecular weight of 2279.59 g/mol. Its IUPAC name is 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one.

Molecular Properties

• Compound Name: 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one
• PubChem CID: 158187756
• Molecular Formula: C119H98Cl2N28O6S6
• Molecular Weight: 2279.59 g/mol
• Exact Mass: 2276.59
• IUPAC Name: 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one
• SMILES: CC(=O)Cc1cc(-c2nc(-c3ccccc3)c(-c3ncc[nH]3)s2)c(C)cn1.CC(=O)Cc1cc(-c2nc(-c3ccccc3C)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccc(C)cc3)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccc(CO)cc3)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccc(Cl)cc3)c(-c3ncc[nH]3)s2)ccn1.Cc1ccc(-c2nc(-c3ccnc(N)c3)sc2-c2ncc[nH]2)c(Cl)c1
• InChI: InChI=1S/2C21H18N4OS.C20H17N5O2S.C20H17N5OS.C19H14ClN5OS.C18H14ClN5S/c1-13-5-3-4-6-17(13)18-19(20-23-9-10-24-20)27-21(25-18)15-7-8-22-16(12-15)11-14(2)26;1-13-12-24-16(10-14(2)26)11-17(13)21-25-18(15-6-4-3-5-7-15)19(27-21)20-22-8-9-23-20;1-12(27)24-16-10-15(6-7-21-16)20-25-17(14-4-2-13(11-26)3-5-14)18(28-20)19-22-8-9-23-19;1-12-3-5-14(6-4-12)17-18(19-22-9-10-23-19)27-20(25-17)15-7-8-21-16(11-15)24-13(2)26;1-11(26)24-15-10-13(6-7-21-15)19-25-16(12-2-4-14(20)5-3-12)17(27-19)18-22-8-9-23-18;1-10-2-3-12(13(19)8-10)15-16(17-22-6-7-23-17)25-18(24-15)11-4-5-21-14(20)9-11/h3-10,12H,11H2,1-2H3,(H,23,24);3-9,11-12H,10H2,1-2H3,(H,22,23);2-10,26H,11H2,1H3,(H,22,23)(H,21,24,27);3-11H,1-2H3,(H,22,23)(H,21,24,26);2-10H,1H3,(H,22,23)(H,21,24,26);2-9H,1H3,(H2,20,21)(H,22,23)
• InChIKey: FZIVWAJHBMSPEQ-UHFFFAOYSA-N
• XLogP: 27.33
• TPSA: 494.45 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 31
• Rotatable Bonds: 26
• Heavy Atoms: 161
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2279.59
LogP ≤ 5	27.33
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one?

The IUPAC name of 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one (CID 158187756) is 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one.

What is the SMILES notation for 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one?

The canonical SMILES for 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one is CC(=O)Cc1cc(-c2nc(-c3ccccc3)c(-c3ncc[nH]3)s2)c(C)cn1.CC(=O)Cc1cc(-c2nc(-c3ccccc3C)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccc(C)cc3)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccc(CO)cc3)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccc(Cl)cc3)c(-c3ncc[nH]3)s2)ccn1.Cc1ccc(-c2nc(-c3ccnc(N)c3)sc2-c2ncc[nH]2)c(Cl)c1.

What is the InChIKey of 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one?

The InChIKey is FZIVWAJHBMSPEQ-UHFFFAOYSA-N. The full InChI is InChI=1S/2C21H18N4OS.C20H17N5O2S.C20H17N5OS.C19H14ClN5OS.C18H14ClN5S/c1-13-5-3-4-6-17(13)18-19(20-23-9-10-24-20)27-21(25-18)15-7-8-22-16(12-15)11-14(2)26;1-13-12-24-16(10-14(2)26)11-17(13)21-25-18(15-6-4-3-5-7-15)19(27-21)20-22-8-9-23-20;1-12(27)24-16-10-15(6-7-21-16)20-25-17(14-4-2-13(11-26)3-5-14)18(28-20)19-22-8-9-23-19;1-12-3-5-14(6-4-12)17-18(19-22-9-10-23-19)27-20(25-17)15-7-8-21-16(11-15)24-13(2)26;1-11(26)24-15-10-13(6-7-21-15)19-25-16(12-2-4-14(20)5-3-12)17(27-19)18-22-8-9-23-18;1-10-2-3-12(13(19)8-10)15-16(17-22-6-7-23-17)25-18(24-15)11-4-5-21-14(20)9-11/h3-10,12H,11H2,1-2H3,(H,23,24);3-9,11-12H,10H2,1-2H3,(H,22,23);2-10,26H,11H2,1H3,(H,22,23)(H,21,24,27);3-11H,1-2H3,(H,22,23)(H,21,24,26);2-10H,1H3,(H,22,23)(H,21,24,26);2-9H,1H3,(H2,20,21)(H,22,23).

What are the key properties of 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one?

4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one has a molecular weight of 2279.59 g/mol, XLogP of 27.33, 26 rotatable bonds, 11 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for 4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyridin-2-amine;N-[4-[4-(4-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-[4-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(2-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;1-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one is sourced from PubChem (CID 158187756), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).