N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate

C124H103Cl4N29O8S6 — CID 157230911

About N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate

N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate (PubChem CID 157230911) has the molecular formula C124H103Cl4N29O8S6 and a molecular weight of 2461.60 g/mol. Its IUPAC name is N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate.

Molecular Properties

• Compound Name: N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate
• PubChem CID: 157230911
• Molecular Formula: C124H103Cl4N29O8S6
• Molecular Weight: 2461.60 g/mol
• Exact Mass: 2457.56
• IUPAC Name: N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate
• SMILES: CC(=O)Cc1cc(-c2nc(-c3ccc(Cl)cc3Cl)c(-c3nc(C)c(C)[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccc(C)cc3)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccc(C)cc3Cl)c(-c3ncc[nH]3)s2)ncn1.CC(=O)Nc1cc(-c2nc(-c3cccc(C)c3)c(-c3ncc[nH]3)s2)ccn1.CCc1ccc(Cl)c(-c2nc(-c3ccnc(NC(C)=O)c3)sc2-c2ncc[nH]2)c1.COC(=O)c1ccc(-c2nc(-c3ccnc(CC(C)=O)c3)sc2-c2ncc[nH]2)cc1
• InChI: InChI=1S/C22H18Cl2N4OS.C22H18N4O3S.C21H18ClN5OS.2C20H17N5OS.C19H15ClN6OS/c1-11(29)8-16-9-14(6-7-25-16)22-28-19(17-5-4-15(23)10-18(17)24)20(30-22)21-26-12(2)13(3)27-21;1-13(27)11-17-12-16(7-8-23-17)21-26-18(19(30-21)20-24-9-10-25-20)14-3-5-15(6-4-14)22(28)29-2;1-3-13-4-5-16(22)15(10-13)18-19(20-24-8-9-25-20)29-21(27-18)14-6-7-23-17(11-14)26-12(2)28;1-12-3-5-14(6-4-12)17-18(19-22-9-10-23-19)27-20(25-17)15-7-8-21-16(11-15)24-13(2)26;1-12-4-3-5-14(10-12)17-18(19-22-8-9-23-19)27-20(25-17)15-6-7-21-16(11-15)24-13(2)26;1-10-3-4-12(13(20)7-10)16-17(18-21-5-6-22-18)28-19(26-16)14-8-15(24-9-23-14)25-11(2)27/h4-7,9-10H,8H2,1-3H3,(H,26,27);3-10,12H,11H2,1-2H3,(H,24,25);4-11H,3H2,1-2H3,(H,24,25)(H,23,26,28);2*3-11H,1-2H3,(H,22,23)(H,21,24,26);3-9H,1-2H3,(H,21,22)(H,23,24,25,27)
• InChIKey: AUBWZYAYJDITFK-UHFFFAOYSA-N
• XLogP: 29.57
• TPSA: 516.49 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 33
• Rotatable Bonds: 28
• Heavy Atoms: 171
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2461.60
LogP ≤ 5	29.57
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate?

The IUPAC name of N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate (CID 157230911) is N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate.

What is the SMILES notation for N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate?

The canonical SMILES for N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate is CC(=O)Cc1cc(-c2nc(-c3ccc(Cl)cc3Cl)c(-c3nc(C)c(C)[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccc(C)cc3)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccc(C)cc3Cl)c(-c3ncc[nH]3)s2)ncn1.CC(=O)Nc1cc(-c2nc(-c3cccc(C)c3)c(-c3ncc[nH]3)s2)ccn1.CCc1ccc(Cl)c(-c2nc(-c3ccnc(NC(C)=O)c3)sc2-c2ncc[nH]2)c1.COC(=O)c1ccc(-c2nc(-c3ccnc(CC(C)=O)c3)sc2-c2ncc[nH]2)cc1.

What is the InChIKey of N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate?

The InChIKey is AUBWZYAYJDITFK-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H18Cl2N4OS.C22H18N4O3S.C21H18ClN5OS.2C20H17N5OS.C19H15ClN6OS/c1-11(29)8-16-9-14(6-7-25-16)22-28-19(17-5-4-15(23)10-18(17)24)20(30-22)21-26-12(2)13(3)27-21;1-13(27)11-17-12-16(7-8-23-17)21-26-18(19(30-21)20-24-9-10-25-20)14-3-5-15(6-4-14)22(28)29-2;1-3-13-4-5-16(22)15(10-13)18-19(20-24-8-9-25-20)29-21(27-18)14-6-7-23-17(11-14)26-12(2)28;1-12-3-5-14(6-4-12)17-18(19-22-9-10-23-19)27-20(25-17)15-7-8-21-16(11-15)24-13(2)26;1-12-4-3-5-14(10-12)17-18(19-22-8-9-23-19)27-20(25-17)15-6-7-21-16(11-15)24-13(2)26;1-10-3-4-12(13(20)7-10)16-17(18-21-5-6-22-18)28-19(26-16)14-8-15(24-9-23-14)25-11(2)27/h4-7,9-10H,8H2,1-3H3,(H,26,27);3-10,12H,11H2,1-2H3,(H,24,25);4-11H,3H2,1-2H3,(H,24,25)(H,23,26,28);2*3-11H,1-2H3,(H,22,23)(H,21,24,26);3-9H,1-2H3,(H,21,22)(H,23,24,25,27).

What are the key properties of N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate?

N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate has a molecular weight of 2461.60 g/mol, XLogP of 29.57, 28 rotatable bonds, 10 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate is sourced from PubChem (CID 157230911), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).