1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide

C127H109Cl2FN30O8S6 — CID 160718496

IUPAC1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide
SMILESCC(=O)Cc1cc(-c2nc(-c3ccc(C)cc3Cl)c(-c3ncc[nH]3)s2)c(C)cn1.CC(=O)Cc1cc(-c2nc(-c3ccc(N(C)C)cc3)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Cc1cc(-c2nc(-c3ccccc3Cl)c(-c3ncc[nH]3)s2)c(C)cn1.CC(=O)Nc1cc(-c2nc(-c3cc(C(=O)N4CCCC4)ccc3F)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccccc3)c(-c3ncc[nH]3)s2)ccn1.COc1ncccc1-c1nc(-c2ccnc(NC(C)=O)c2)sc1-c1ncc[nH]1
InChIInChI=1S/C24H21FN6O2S.C22H19ClN4OS.C22H21N5OS.C21H17ClN4OS.C19H16N6O2S.C19H15N5OS/c1-14(32)29-19-13-15(6-7-26-19)23-30-20(21(34-23)22-27-8-9-28-22)17-12-16(4-5-18(17)25)24(33)31-10-2-3-11-31;1-12-4-5-16(18(23)8-12)19-20(21-24-6-7-25-21)29-22(27-19)17-10-15(9-14(3)28)26-11-13(17)2;1-14(28)12-17-13-16(8-9-23-17)22-26-19(20(29-22)21-24-10-11-25-21)15-4-6-18(7-5-15)27(2)3;1-12-11-25-14(9-13(2)27)10-16(12)21-26-18(15-5-3-4-6-17(15)22)19(28-21)20-23-7-8-24-20;1-11(26)24-14-10-12(5-7-20-14)19-25-15(13-4-3-6-23-18(13)27-2)16(28-19)17-21-8-9-22-17;1-12(25)23-15-11-14(7-8-20-15)19-24-16(13-5-3-2-4-6-13)17(26-19)18-21-9-10-22-18/h4-9,12-13H,2-3,10-11H2,1H3,(H,27,28)(H,26,29,32);4-8,10-11H,9H2,1-3H3,(H,24,25);4-11,13H,12H2,1-3H3,(H,24,25);3-8,10-11H,9H2,1-2H3,(H,23,24);3-10H,1-2H3,(H,21,22)(H,20,24,26);2-11H,1H3,(H,21,22)(H,20,23,25)
InChIKeyRSUBQECOTLBUKG-UHFFFAOYSA-N
MW2465.78 g/mol
LogP27.92
Rot. Bonds30

About 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide

1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide (PubChem CID 160718496) has the molecular formula C127H109Cl2FN30O8S6 and a molecular weight of 2465.78 g/mol. Its IUPAC name is 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide.

Molecular Properties

Compound Name1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide
PubChem CID160718496
Molecular FormulaC127H109Cl2FN30O8S6
Molecular Weight2465.78 g/mol
Exact Mass2462.67
IUPAC Name1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide
SMILESCC(=O)Cc1cc(-c2nc(-c3ccc(C)cc3Cl)c(-c3ncc[nH]3)s2)c(C)cn1.CC(=O)Cc1cc(-c2nc(-c3ccc(N(C)C)cc3)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Cc1cc(-c2nc(-c3ccccc3Cl)c(-c3ncc[nH]3)s2)c(C)cn1.CC(=O)Nc1cc(-c2nc(-c3cc(C(=O)N4CCCC4)ccc3F)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccccc3)c(-c3ncc[nH]3)s2)ccn1.COc1ncccc1-c1nc(-c2ccnc(NC(C)=O)c2)sc1-c1ncc[nH]1
InChIInChI=1S/C24H21FN6O2S.C22H19ClN4OS.C22H21N5OS.C21H17ClN4OS.C19H16N6O2S.C19H15N5OS/c1-14(32)29-19-13-15(6-7-26-19)23-30-20(21(34-23)22-27-8-9-28-22)17-12-16(4-5-18(17)25)24(33)31-10-2-3-11-31;1-12-4-5-16(18(23)8-12)19-20(21-24-6-7-25-21)29-22(27-19)17-10-15(9-14(3)28)26-11-13(17)2;1-14(28)12-17-13-16(8-9-23-17)22-26-19(20(29-22)21-24-10-11-25-21)15-4-6-18(7-5-15)27(2)3;1-12-11-25-14(9-13(2)27)10-16(12)21-26-18(15-5-3-4-6-17(15)22)19(28-21)20-23-7-8-24-20;1-11(26)24-14-10-12(5-7-20-14)19-25-15(13-4-3-6-23-18(13)27-2)16(28-19)17-21-8-9-22-17;1-12(25)23-15-11-14(7-8-20-15)19-24-16(13-5-3-2-4-6-13)17(26-19)18-21-9-10-22-18/h4-9,12-13H,2-3,10-11H2,1H3,(H,27,28)(H,26,29,32);4-8,10-11H,9H2,1-3H3,(H,24,25);4-11,13H,12H2,1-3H3,(H,24,25);3-8,10-11H,9H2,1-2H3,(H,23,24);3-10H,1-2H3,(H,21,22)(H,20,24,26);2-11H,1H3,(H,21,22)(H,20,23,25)
InChIKeyRSUBQECOTLBUKG-UHFFFAOYSA-N
XLogP27.92
TPSA510.94 Ų
H-Bond Donors9
H-Bond Acceptors34
Rotatable Bonds30
Heavy Atoms174
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002465.78
LogP ≤ 527.92
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1034

Analyze 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[4-[4-[2-chloro-5-(hydroxymethyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[6-[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate
CID 157565455
6-[2-chloro-4-(1-methylpyrrolidin-3-yl)phenyl]-2-[4-[(1-methylpyrrolidin-3-yl)amino]anilino]-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one;6-(3-chloro-5-piperidin-2-yl-2-pyridinyl)-2-[4-(4-methylmorpholin-2-yl)anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-[4-methyl-2-(1-methylpyrrolidin-2-yl)phenyl]-2-[4-(piperidin-4-ylamino)anilino]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;6-(4-methyl-2-thiophen-3-yl-3H-pyrrol-5-yl)-8-phenyl-2-[4-(piperidin-3-ylamino)anilino]pyrido[2,3-d]pyrimidin-7-one;8-(oxan-4-ylmethyl)-2-(4-piperidin-3-yloxyanilino)-6-[4-piperidin-3-yl-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one
CID 159571592
N-[4-[4-(6-amino-3-pyridinyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-(1,3-benzodioxol-5-yl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[4-(2-chloro-4-methoxyphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(5-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-[4-(piperazine-1-carbonyl)phenyl]-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]-2-pyridinyl]acetamide
CID 161419017
6-(4-Cyclohexylphenyl)-2-[4-(4-methylthiomorpholin-2-yl)anilino]-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one;6-[2,6-dichloro-4-(1-methylpyrrolidin-2-yl)phenyl]-8-[2-(dimethylamino)ethyl]-2-[4-[methyl(piperidin-3-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;methane;2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxolan-3-yl)-6-[4-(1,3-thiazol-4-yl)-2-(trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpiperidin-3-yl)oxyanilino]-6-[1-(1-methylpyrrolidin-3-yl)imidazol-2-yl]-8-phenylpyrido[2,3-d]pyrimidin-7-one;2-[4-(1-methylpiperidin-4-yl)oxyanilino]-6-(2-piperidin-2-ylphenyl)-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one
CID 161658037
N-[4-[4-(2-chloro-5-ethylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[6-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]pyrimidin-4-yl]acetamide;1-[4-[4-(2,4-dichlorophenyl)-5-(4,5-dimethyl-1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(3-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(4-methylphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;methyl 4-[5-(1H-imidazol-2-yl)-2-[2-(2-oxopropyl)-4-pyridinyl]-1,3-thiazol-4-yl]benzoate
CID 157230911
N-[4-[4-bromo-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[4-(2-chlorophenyl)-5-(4-methoxybutanoyl)thiophen-2-yl]-2-pyridinyl]acetamide;N-[4-[4-(2-fluoro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-(6-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-(4-phenoxyphenyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;1-[4-[5-(1H-imidazol-2-yl)-4-[4-(prop-1-en-2-ylamino)phenyl]-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one
CID 157310344
1-[4-[4-(2-chlorophenyl)-5-(1H-1,2,4-triazol-5-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide
CID 157969233
N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide
CID 158633930
N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[5-(4-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide
CID 159105016
N-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propanamide;4-[4-(2-chloro-5-propylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-N-ethylpyridin-2-amine;1-[4-[4-[6-(dimethylamino)-3-pyridinyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[5-(1H-imidazol-2-yl)-4-isoquinolin-5-yl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-[4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]-1,3-thiazol-2-yl]-2-pyridinyl]acetamide
CID 159603809
N-(4-benzyl-1,3-thiazol-2-yl)-9-ethyl-12-methyl-10-oxo-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-triene-12-carboxamide;bis(N-[4-[3-[(3-chloro-4-methoxyphenyl)carbamoyl]phenyl]-1,3-thiazol-2-yl]-9,12-dimethyl-10-oxo-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-triene-12-carboxamide);N-[5-(4-fluoronaphthalen-1-yl)-1H-imidazol-2-yl]-4,12-dimethyl-10-oxo-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene-12-carboxamide;N-[5-(4-fluoronaphthalen-1-yl)-1H-imidazol-2-yl]-4,9,12-trimethyl-10-oxo-9-azatricyclo[6.2.2.02,7]dodeca-2(7),3,5-triene-12-carboxamide;N-[4-(4-fluoronaphthalen-1-yl)-1,3-thiazol-2-yl]-6,12-dimethyl-10-oxo-9-azatricyclo[6.2.2.02,7]dodeca-2,4,6-triene-12-carboxamide
CID 159752316
1-[4-(4-Acetylphenyl)piperazin-1-yl]-2-(5-propan-2-yl-1,3-thiazol-2-yl)ethanone;1-[4-(3-chlorophenyl)piperazin-1-yl]-2-(5-methyl-1,3-thiazol-2-yl)ethanone;1-[4-(4-fluorophenyl)piperazin-1-yl]-2-(5-propan-2-yl-1,3-thiazol-2-yl)ethanone;1-[4-(4-methoxyphenyl)piperazin-1-yl]-2-(5-propan-2-yl-1,3-thiazol-2-yl)ethanone;2-[6-methyl-2-(3-phenoxypropyl)imidazo[4,5-b]pyridin-3-yl]ethanamine;3-[6-methyl-2-(3-phenoxypropyl)imidazo[4,5-b]pyridin-3-yl]propan-1-amine;1-(5-methyl-1,3-thiazol-2-yl)-5-phenoxypentan-2-one
CID 160144635

Frequently Asked Questions

What is the IUPAC name of 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide?
The IUPAC name of 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide (CID 160718496) is 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide.
What is the SMILES notation for 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide?
The canonical SMILES for 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide is CC(=O)Cc1cc(-c2nc(-c3ccc(C)cc3Cl)c(-c3ncc[nH]3)s2)c(C)cn1.CC(=O)Cc1cc(-c2nc(-c3ccc(N(C)C)cc3)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Cc1cc(-c2nc(-c3ccccc3Cl)c(-c3ncc[nH]3)s2)c(C)cn1.CC(=O)Nc1cc(-c2nc(-c3cc(C(=O)N4CCCC4)ccc3F)c(-c3ncc[nH]3)s2)ccn1.CC(=O)Nc1cc(-c2nc(-c3ccccc3)c(-c3ncc[nH]3)s2)ccn1.COc1ncccc1-c1nc(-c2ccnc(NC(C)=O)c2)sc1-c1ncc[nH]1.
What is the InChIKey of 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide?
The InChIKey is RSUBQECOTLBUKG-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H21FN6O2S.C22H19ClN4OS.C22H21N5OS.C21H17ClN4OS.C19H16N6O2S.C19H15N5OS/c1-14(32)29-19-13-15(6-7-26-19)23-30-20(21(34-23)22-27-8-9-28-22)17-12-16(4-5-18(17)25)24(33)31-10-2-3-11-31;1-12-4-5-16(18(23)8-12)19-20(21-24-6-7-25-21)29-22(27-19)17-10-15(9-14(3)28)26-11-13(17)2;1-14(28)12-17-13-16(8-9-23-17)22-26-19(20(29-22)21-24-10-11-25-21)15-4-6-18(7-5-15)27(2)3;1-12-11-25-14(9-13(2)27)10-16(12)21-26-18(15-5-3-4-6-17(15)22)19(28-21)20-23-7-8-24-20;1-11(26)24-14-10-12(5-7-20-14)19-25-15(13-4-3-6-23-18(13)27-2)16(28-19)17-21-8-9-22-17;1-12(25)23-15-11-14(7-8-20-15)19-24-16(13-5-3-2-4-6-13)17(26-19)18-21-9-10-22-18/h4-9,12-13H,2-3,10-11H2,1H3,(H,27,28)(H,26,29,32);4-8,10-11H,9H2,1-3H3,(H,24,25);4-11,13H,12H2,1-3H3,(H,24,25);3-8,10-11H,9H2,1-2H3,(H,23,24);3-10H,1-2H3,(H,21,22)(H,20,24,26);2-11H,1H3,(H,21,22)(H,20,23,25).
What are the key properties of 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide?
1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide has a molecular weight of 2465.78 g/mol, XLogP of 27.92, 30 rotatable bonds, 9 hydrogen bond donors, and 34 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[4-[4-(2-chloro-4-methylphenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-(2-chlorophenyl)-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-5-methyl-2-pyridinyl]propan-2-one;1-[4-[4-[4-(dimethylamino)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]propan-2-one;N-[4-[4-[2-fluoro-5-(pyrrolidine-1-carbonyl)phenyl]-5-(1H-imidazol-2-yl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-(2-methoxy-3-pyridinyl)-1,3-thiazol-2-yl]-2-pyridinyl]acetamide;N-[4-[5-(1H-imidazol-2-yl)-4-phenyl-1,3-thiazol-2-yl]-2-pyridinyl]acetamide is sourced from PubChem (CID 160718496), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).