N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide

C173H121Cl2F16N25O9S10 — CID 158633930

About N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide

N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide (PubChem CID 158633930) has the molecular formula C173H121Cl2F16N25O9S10 and a molecular weight of 3389.58 g/mol. Its IUPAC name is N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide.

Molecular Properties

• Compound Name: N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide
• PubChem CID: 158633930
• Molecular Formula: C173H121Cl2F16N25O9S10
• Molecular Weight: 3389.58 g/mol
• Exact Mass: 3385.61
• IUPAC Name: N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide
• SMILES: COc1ncc(Cl)cc1-c1cc(-c2ccc(NC(=O)c3c(F)cccc3F)cc2)c(C)s1.Cc1ccncc1-c1cc(-c2ccc(NC(=O)c3c(F)cccc3F)cc2)c(C)s1.Cc1ccncc1-c1cc(-c2ccc(NC(=O)c3c(F)cccc3F)cc2)c(C)s1.Cc1sc(-c2cnc[nH]2)cc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1.Cc1sc(-c2cnccc2Cl)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cncn2C)cc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1.Cc1sc(-c2nccs2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cc1sc(-c2nccs2)cc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1
• InChI: InChI=1S/C24H17ClF2N2O2S.2C24H18F2N2OS.C23H15ClF2N2OS.C20H15F2N5OS.C20H13F2N3OS2.C19H13F2N5OS.C19H12F2N4OS2/c1-13-17(11-21(32-13)18-10-15(25)12-28-24(18)31-2)14-6-8-16(9-7-14)29-23(30)22-19(26)4-3-5-20(22)27;2*1-14-10-11-27-13-19(14)22-12-18(15(2)30-22)16-6-8-17(9-7-16)28-24(29)23-20(25)4-3-5-21(23)26;1-13-16(11-21(30-13)17-12-27-10-9-18(17)24)14-5-7-15(8-6-14)28-23(29)22-19(25)3-2-4-20(22)26;1-11-12(6-17(29-11)16-8-23-10-27(16)2)15-7-25-18(9-24-15)26-20(28)19-13(21)4-3-5-14(19)22;1-11-13(9-16(28-11)20-23-7-8-27-20)12-5-6-17(24-10-12)25-19(26)18-14(21)3-2-4-15(18)22;1-10-11(5-16(28-10)15-6-22-9-25-15)14-7-24-17(8-23-14)26-19(27)18-12(20)3-2-4-13(18)21;1-10-11(7-15(28-10)19-22-5-6-27-19)14-8-24-16(9-23-14)25-18(26)17-12(20)3-2-4-13(17)21/h3-12H,1-2H3,(H,29,30);2*3-13H,1-2H3,(H,28,29);2-12H,1H3,(H,28,29);3-10H,1-2H3,(H,25,26,28);2-10H,1H3,(H,24,25,26);2-9H,1H3,(H,22,25)(H,24,26,27);2-9H,1H3,(H,24,25,26)
• InChIKey: HZNMOHVDPFRHDX-UHFFFAOYSA-N
• XLogP: 47.01
• TPSA: 456.10 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 35
• Rotatable Bonds: 33
• Heavy Atoms: 235
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3389.58
LogP ≤ 5	47.01
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide?

The IUPAC name of N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide (CID 158633930) is N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide.

What is the SMILES notation for N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide?

The canonical SMILES for N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide is COc1ncc(Cl)cc1-c1cc(-c2ccc(NC(=O)c3c(F)cccc3F)cc2)c(C)s1.Cc1ccncc1-c1cc(-c2ccc(NC(=O)c3c(F)cccc3F)cc2)c(C)s1.Cc1ccncc1-c1cc(-c2ccc(NC(=O)c3c(F)cccc3F)cc2)c(C)s1.Cc1sc(-c2cnc[nH]2)cc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1.Cc1sc(-c2cnccc2Cl)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1.Cc1sc(-c2cncn2C)cc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1.Cc1sc(-c2nccs2)cc1-c1ccc(NC(=O)c2c(F)cccc2F)nc1.Cc1sc(-c2nccs2)cc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1.

What is the InChIKey of N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide?

The InChIKey is HZNMOHVDPFRHDX-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H17ClF2N2O2S.2C24H18F2N2OS.C23H15ClF2N2OS.C20H15F2N5OS.C20H13F2N3OS2.C19H13F2N5OS.C19H12F2N4OS2/c1-13-17(11-21(32-13)18-10-15(25)12-28-24(18)31-2)14-6-8-16(9-7-14)29-23(30)22-19(26)4-3-5-20(22)27;2*1-14-10-11-27-13-19(14)22-12-18(15(2)30-22)16-6-8-17(9-7-16)28-24(29)23-20(25)4-3-5-21(23)26;1-13-16(11-21(30-13)17-12-27-10-9-18(17)24)14-5-7-15(8-6-14)28-23(29)22-19(25)3-2-4-20(22)26;1-11-12(6-17(29-11)16-8-23-10-27(16)2)15-7-25-18(9-24-15)26-20(28)19-13(21)4-3-5-14(19)22;1-11-13(9-16(28-11)20-23-7-8-27-20)12-5-6-17(24-10-12)25-19(26)18-14(21)3-2-4-15(18)22;1-10-11(5-16(28-10)15-6-22-9-25-15)14-7-24-17(8-23-14)26-19(27)18-12(20)3-2-4-13(18)21;1-10-11(7-15(28-10)19-22-5-6-27-19)14-8-24-16(9-23-14)25-18(26)17-12(20)3-2-4-13(17)21/h3-12H,1-2H3,(H,29,30);2*3-13H,1-2H3,(H,28,29);2-12H,1H3,(H,28,29);3-10H,1-2H3,(H,25,26,28);2-10H,1H3,(H,24,25,26);2-9H,1H3,(H,22,25)(H,24,26,27);2-9H,1H3,(H,24,25,26).

What are the key properties of N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide?

N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide has a molecular weight of 3389.58 g/mol, XLogP of 47.01, 33 rotatable bonds, 9 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for N-[4-[5-(5-chloro-2-methoxy-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;N-[4-[5-(4-chloro-3-pyridinyl)-2-methylthiophen-3-yl]phenyl]-2,6-difluorobenzamide;2,6-difluoro-N-[5-[5-(1H-imidazol-5-yl)-2-methylthiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(3-methylimidazol-4-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;bis(2,6-difluoro-N-[4-[2-methyl-5-(4-methyl-3-pyridinyl)thiophen-3-yl]phenyl]benzamide);2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]pyrazin-2-yl]benzamide;2,6-difluoro-N-[5-[2-methyl-5-(1,3-thiazol-2-yl)thiophen-3-yl]-2-pyridinyl]benzamide is sourced from PubChem (CID 158633930), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).