N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide

C265H329F10N31O21 — CID 158203156

IUPACN-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide
SMILESCC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC(C)C)cc3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC4CCC4)cc3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4(F)F)cc3F)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4)cc3F)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(C(F)(F)F)n3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(Oc4cncnc4)c3)CC2)cc1.CCC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4)cc3)CC2)cc1.CCOc1cc(N2CCC(c3ccc([C@H](C)NC(=O)N(C)C)cc3)CC2)ccn1.CCOc1ccc(N2CCC(c3ccc([C@H](C)NC(C)=O)cc3)CC2)c(C#N)n1.CCOc1ccc(N2CCC(c3ccc([C@H](C)NC(C)=O)cc3)CC2)c(F)c1.C[C@H](NC(=O)C1CC1)c1ccc(C2CCN(c3ccc(OCC4CC4(F)F)cc3)CC2)cc1
InChIInChI=1S/C27H32F2N2O2.C26H34N2O2.C25H29F3N2O2.C25H31FN2O2.C25H32N2O2.C24H27N5O2.C24H32N2O2.C23H29FN2O2.C23H32N4O2.C23H28N4O2.C20H23F3N4O/c1-18(30-26(32)22-6-7-22)19-2-4-20(5-3-19)21-12-14-31(15-13-21)24-8-10-25(11-9-24)33-17-23-16-27(23,28)29;1-3-26(29)27-19(2)21-6-8-22(9-7-21)23-14-16-28(17-15-23)24-10-12-25(13-11-24)30-18-20-4-5-20;1-16(29-17(2)31)18-3-5-19(6-4-18)20-9-11-30(12-10-20)24-8-7-22(13-23(24)26)32-15-21-14-25(21,27)28;1-17(27-18(2)29)20-5-7-21(8-6-20)22-11-13-28(14-12-22)25-10-9-23(15-24(25)26)30-16-19-3-4-19;1-18(26-19(2)28)20-6-8-21(9-7-20)22-14-16-27(17-15-22)23-10-12-25(13-11-23)29-24-4-3-5-24;1-17(28-18(2)30)19-3-5-20(6-4-19)21-8-11-29(12-9-21)22-7-10-27-24(13-22)31-23-14-25-16-26-15-23;1-17(2)28-24-11-9-23(10-12-24)26-15-13-22(14-16-26)21-7-5-20(6-8-21)18(3)25-19(4)27;1-4-28-21-9-10-23(22(24)15-21)26-13-11-20(12-14-26)19-7-5-18(6-8-19)16(2)25-17(3)27;1-5-29-22-16-21(10-13-24-22)27-14-11-20(12-15-27)19-8-6-18(7-9-19)17(2)25-23(28)26(3)4;1-4-29-23-10-9-22(21(15-24)26-23)27-13-11-20(12-14-27)19-7-5-18(6-8-19)16(2)25-17(3)28;1-13(25-14(2)28)15-3-5-16(6-4-15)17-8-11-27(12-9-17)18-7-10-24-19(26-18)20(21,22)23/h2-5,8-11,18,21-23H,6-7,12-17H2,1H3,(H,30,32);6-13,19-20,23H,3-5,14-18H2,1-2H3,(H,27,29);3-8,13,16,20-21H,9-12,14-15H2,1-2H3,(H,29,31);5-10,15,17,19,22H,3-4,11-14,16H2,1-2H3,(H,27,29);6-13,18,22,24H,3-5,14-17H2,1-2H3,(H,26,28);3-7,10,13-17,21H,8-9,11-12H2,1-2H3,(H,28,30);5-12,17-18,22H,13-16H2,1-4H3,(H,25,27);5-10,15-16,20H,4,11-14H2,1-3H3,(H,25,27);6-10,13,16-17,20H,5,11-12,14-15H2,1-4H3,(H,25,28);5-10,16,20H,4,11-14H2,1-3H3,(H,25,28);3-7,10,13,17H,8-9,11-12H2,1-2H3,(H,25,28)/t18-,23?;19-;16-,21?;17-;18-;17-;18-;16-;17-;16-;13-/m00000000000/s1
InChIKeyGBEJCCWYFMNHQT-IXRLKQFBSA-N
MW4474.72 g/mol
LogP53.29
Rot. Bonds70

About N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide

N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide (PubChem CID 158203156) has the molecular formula C265H329F10N31O21 and a molecular weight of 4474.72 g/mol. Its IUPAC name is N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide.

Molecular Properties

Compound NameN-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide
PubChem CID158203156
Molecular FormulaC265H329F10N31O21
Molecular Weight4474.72 g/mol
Exact Mass4471.55
IUPAC NameN-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide
SMILESCC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC(C)C)cc3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC4CCC4)cc3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4(F)F)cc3F)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4)cc3F)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(C(F)(F)F)n3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(Oc4cncnc4)c3)CC2)cc1.CCC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4)cc3)CC2)cc1.CCOc1cc(N2CCC(c3ccc([C@H](C)NC(=O)N(C)C)cc3)CC2)ccn1.CCOc1ccc(N2CCC(c3ccc([C@H](C)NC(C)=O)cc3)CC2)c(C#N)n1.CCOc1ccc(N2CCC(c3ccc([C@H](C)NC(C)=O)cc3)CC2)c(F)c1.C[C@H](NC(=O)C1CC1)c1ccc(C2CCN(c3ccc(OCC4CC4(F)F)cc3)CC2)cc1
InChIInChI=1S/C27H32F2N2O2.C26H34N2O2.C25H29F3N2O2.C25H31FN2O2.C25H32N2O2.C24H27N5O2.C24H32N2O2.C23H29FN2O2.C23H32N4O2.C23H28N4O2.C20H23F3N4O/c1-18(30-26(32)22-6-7-22)19-2-4-20(5-3-19)21-12-14-31(15-13-21)24-8-10-25(11-9-24)33-17-23-16-27(23,28)29;1-3-26(29)27-19(2)21-6-8-22(9-7-21)23-14-16-28(17-15-23)24-10-12-25(13-11-24)30-18-20-4-5-20;1-16(29-17(2)31)18-3-5-19(6-4-18)20-9-11-30(12-10-20)24-8-7-22(13-23(24)26)32-15-21-14-25(21,27)28;1-17(27-18(2)29)20-5-7-21(8-6-20)22-11-13-28(14-12-22)25-10-9-23(15-24(25)26)30-16-19-3-4-19;1-18(26-19(2)28)20-6-8-21(9-7-20)22-14-16-27(17-15-22)23-10-12-25(13-11-23)29-24-4-3-5-24;1-17(28-18(2)30)19-3-5-20(6-4-19)21-8-11-29(12-9-21)22-7-10-27-24(13-22)31-23-14-25-16-26-15-23;1-17(2)28-24-11-9-23(10-12-24)26-15-13-22(14-16-26)21-7-5-20(6-8-21)18(3)25-19(4)27;1-4-28-21-9-10-23(22(24)15-21)26-13-11-20(12-14-26)19-7-5-18(6-8-19)16(2)25-17(3)27;1-5-29-22-16-21(10-13-24-22)27-14-11-20(12-15-27)19-8-6-18(7-9-19)17(2)25-23(28)26(3)4;1-4-29-23-10-9-22(21(15-24)26-23)27-13-11-20(12-14-27)19-7-5-18(6-8-19)16(2)25-17(3)28;1-13(25-14(2)28)15-3-5-16(6-4-15)17-8-11-27(12-9-17)18-7-10-24-19(26-18)20(21,22)23/h2-5,8-11,18,21-23H,6-7,12-17H2,1H3,(H,30,32);6-13,19-20,23H,3-5,14-18H2,1-2H3,(H,27,29);3-8,13,16,20-21H,9-12,14-15H2,1-2H3,(H,29,31);5-10,15,17,19,22H,3-4,11-14,16H2,1-2H3,(H,27,29);6-13,18,22,24H,3-5,14-17H2,1-2H3,(H,26,28);3-7,10,13-17,21H,8-9,11-12H2,1-2H3,(H,28,30);5-12,17-18,22H,13-16H2,1-4H3,(H,25,27);5-10,15-16,20H,4,11-14H2,1-3H3,(H,25,27);6-10,13,16-17,20H,5,11-12,14-15H2,1-4H3,(H,25,28);5-10,16,20H,4,11-14H2,1-3H3,(H,25,28);3-7,10,13,17H,8-9,11-12H2,1-2H3,(H,25,28)/t18-,23?;19-;16-,21?;17-;18-;17-;18-;16-;17-;16-;13-/m00000000000/s1
InChIKeyGBEJCCWYFMNHQT-IXRLKQFBSA-N
XLogP53.29
TPSA565.30 Ų
H-Bond Donors11
H-Bond Acceptors40
Rotatable Bonds70
Heavy Atoms327
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004474.72
LogP ≤ 553.29
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1040

Analyze N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide?
The IUPAC name of N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide (CID 158203156) is N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide.
What is the SMILES notation for N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide?
The canonical SMILES for N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide is CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC(C)C)cc3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC4CCC4)cc3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4(F)F)cc3F)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4)cc3F)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(C(F)(F)F)n3)CC2)cc1.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccnc(Oc4cncnc4)c3)CC2)cc1.CCC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OCC4CC4)cc3)CC2)cc1.CCOc1cc(N2CCC(c3ccc([C@H](C)NC(=O)N(C)C)cc3)CC2)ccn1.CCOc1ccc(N2CCC(c3ccc([C@H](C)NC(C)=O)cc3)CC2)c(C#N)n1.CCOc1ccc(N2CCC(c3ccc([C@H](C)NC(C)=O)cc3)CC2)c(F)c1.C[C@H](NC(=O)C1CC1)c1ccc(C2CCN(c3ccc(OCC4CC4(F)F)cc3)CC2)cc1.
What is the InChIKey of N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide?
The InChIKey is GBEJCCWYFMNHQT-IXRLKQFBSA-N. The full InChI is InChI=1S/C27H32F2N2O2.C26H34N2O2.C25H29F3N2O2.C25H31FN2O2.C25H32N2O2.C24H27N5O2.C24H32N2O2.C23H29FN2O2.C23H32N4O2.C23H28N4O2.C20H23F3N4O/c1-18(30-26(32)22-6-7-22)19-2-4-20(5-3-19)21-12-14-31(15-13-21)24-8-10-25(11-9-24)33-17-23-16-27(23,28)29;1-3-26(29)27-19(2)21-6-8-22(9-7-21)23-14-16-28(17-15-23)24-10-12-25(13-11-24)30-18-20-4-5-20;1-16(29-17(2)31)18-3-5-19(6-4-18)20-9-11-30(12-10-20)24-8-7-22(13-23(24)26)32-15-21-14-25(21,27)28;1-17(27-18(2)29)20-5-7-21(8-6-20)22-11-13-28(14-12-22)25-10-9-23(15-24(25)26)30-16-19-3-4-19;1-18(26-19(2)28)20-6-8-21(9-7-20)22-14-16-27(17-15-22)23-10-12-25(13-11-23)29-24-4-3-5-24;1-17(28-18(2)30)19-3-5-20(6-4-19)21-8-11-29(12-9-21)22-7-10-27-24(13-22)31-23-14-25-16-26-15-23;1-17(2)28-24-11-9-23(10-12-24)26-15-13-22(14-16-26)21-7-5-20(6-8-21)18(3)25-19(4)27;1-4-28-21-9-10-23(22(24)15-21)26-13-11-20(12-14-26)19-7-5-18(6-8-19)16(2)25-17(3)27;1-5-29-22-16-21(10-13-24-22)27-14-11-20(12-15-27)19-8-6-18(7-9-19)17(2)25-23(28)26(3)4;1-4-29-23-10-9-22(21(15-24)26-23)27-13-11-20(12-14-27)19-7-5-18(6-8-19)16(2)25-17(3)28;1-13(25-14(2)28)15-3-5-16(6-4-15)17-8-11-27(12-9-17)18-7-10-24-19(26-18)20(21,22)23/h2-5,8-11,18,21-23H,6-7,12-17H2,1H3,(H,30,32);6-13,19-20,23H,3-5,14-18H2,1-2H3,(H,27,29);3-8,13,16,20-21H,9-12,14-15H2,1-2H3,(H,29,31);5-10,15,17,19,22H,3-4,11-14,16H2,1-2H3,(H,27,29);6-13,18,22,24H,3-5,14-17H2,1-2H3,(H,26,28);3-7,10,13-17,21H,8-9,11-12H2,1-2H3,(H,28,30);5-12,17-18,22H,13-16H2,1-4H3,(H,25,27);5-10,15-16,20H,4,11-14H2,1-3H3,(H,25,27);6-10,13,16-17,20H,5,11-12,14-15H2,1-4H3,(H,25,28);5-10,16,20H,4,11-14H2,1-3H3,(H,25,28);3-7,10,13,17H,8-9,11-12H2,1-2H3,(H,25,28)/t18-,23?;19-;16-,21?;17-;18-;17-;18-;16-;17-;16-;13-/m00000000000/s1.
What are the key properties of N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide?
N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide has a molecular weight of 4474.72 g/mol, XLogP of 53.29, 70 rotatable bonds, 11 hydrogen bond donors, and 40 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1S)-1-[4-[1-(2-cyano-6-ethoxy-3-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(4-cyclobutyloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-(cyclopropylmethoxy)phenyl]piperidin-4-yl]phenyl]ethyl]propanamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]-2-fluorophenyl]piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[4-[(2,2-difluorocyclopropyl)methoxy]phenyl]piperidin-4-yl]phenyl]ethyl]cyclopropanecarboxamide;N-[(1S)-1-[4-[1-(4-ethoxy-2-fluorophenyl)piperidin-4-yl]phenyl]ethyl]acetamide;3-[(1S)-1-[4-[1-(2-ethoxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]-1,1-dimethylurea;N-[(1S)-1-[4-[1-(4-propan-2-yloxyphenyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-(2-pyrimidin-5-yloxy-4-pyridinyl)piperidin-4-yl]phenyl]ethyl]acetamide;N-[(1S)-1-[4-[1-[2-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]phenyl]ethyl]acetamide is sourced from PubChem (CID 158203156), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).