2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide

C179H184F6N28O30S2 — CID 158211332

IUPAC2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide
SMILESCCC1(CC)CC[C@@H](c2cc(F)cc(F)c2)N(CC(=O)Nc2ccc3c(c2)C[C@@]2(C3)C(=O)NC(=O)N2C)C1=O.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3C(=O)C(C)(C)CC[C@H]3c3ccccc3)cc1C2.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3C(=O)CS(=O)(=O)C[C@H]3c3cc(F)cc(F)c3)cc1C2.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3C(=O)CSC[C@H]3c3cc(F)cc(F)c3)cc1C2.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3CCC[C@H](c4ccccc4)C3=O)cc1C2.CN1C(=O)NC(=O)[C@]12Cc1ccc(NC(=O)CN3CCC[C@@H](c4ccccc4)C3=O)cc1C2.CN1C(=O)NC(=O)[C@]12Cc1ccc(NC(=O)CN3CCC[C@H](c4ccccc4)C3=O)cc1C2
InChIInChI=1S/C29H32F2N4O4.C27H30N4O4.3C25H26N4O4.C24H22F2N4O6S.C24H22F2N4O4S/c1-4-28(5-2)9-8-23(18-10-20(30)13-21(31)11-18)35(26(28)38)16-24(36)32-22-7-6-17-14-29(15-19(17)12-22)25(37)33-27(39)34(29)3;1-26(2)12-11-21(17-7-5-4-6-8-17)31(24(26)34)16-22(32)28-20-10-9-18-14-27(15-19(18)13-20)23(33)29-25(35)30(27)3;3*1-28-24(33)27-23(32)25(28)13-17-9-10-19(12-18(17)14-25)26-21(30)15-29-11-5-8-20(22(29)31)16-6-3-2-4-7-16;1-29-23(34)28-22(33)24(29)8-13-2-3-18(6-15(13)9-24)27-20(31)10-30-19(11-37(35,36)12-21(30)32)14-4-16(25)7-17(26)5-14;1-29-23(34)28-22(33)24(29)8-13-2-3-18(6-15(13)9-24)27-20(31)10-30-19(11-35-12-21(30)32)14-4-16(25)7-17(26)5-14/h6-7,10-13,23H,4-5,8-9,14-16H2,1-3H3,(H,32,36)(H,33,37,39);4-10,13,21H,11-12,14-16H2,1-3H3,(H,28,32)(H,29,33,35);3*2-4,6-7,9-10,12,20H,5,8,11,13-15H2,1H3,(H,26,30)(H,27,32,33);2-7,19H,8-12H2,1H3,(H,27,31)(H,28,33,34);2-7,19H,8-12H2,1H3,(H,27,31)(H,28,33,34)/t23-,29-;21-,27-;2*20-,25+;20-,25-;2*19-,24-/m0010100/s1
InChIKeyGCCOIWGSCQWDOK-ZKNGECMISA-N
MW3385.73 g/mol
LogP16.44
Rot. Bonds30

About 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide

2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide (PubChem CID 158211332) has the molecular formula C179H184F6N28O30S2 and a molecular weight of 3385.73 g/mol. Its IUPAC name is 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide.

Molecular Properties

Compound Name2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide
PubChem CID158211332
Molecular FormulaC179H184F6N28O30S2
Molecular Weight3385.73 g/mol
Exact Mass3383.31
IUPAC Name2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide
SMILESCCC1(CC)CC[C@@H](c2cc(F)cc(F)c2)N(CC(=O)Nc2ccc3c(c2)C[C@@]2(C3)C(=O)NC(=O)N2C)C1=O.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3C(=O)C(C)(C)CC[C@H]3c3ccccc3)cc1C2.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3C(=O)CS(=O)(=O)C[C@H]3c3cc(F)cc(F)c3)cc1C2.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3C(=O)CSC[C@H]3c3cc(F)cc(F)c3)cc1C2.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3CCC[C@H](c4ccccc4)C3=O)cc1C2.CN1C(=O)NC(=O)[C@]12Cc1ccc(NC(=O)CN3CCC[C@@H](c4ccccc4)C3=O)cc1C2.CN1C(=O)NC(=O)[C@]12Cc1ccc(NC(=O)CN3CCC[C@H](c4ccccc4)C3=O)cc1C2
InChIInChI=1S/C29H32F2N4O4.C27H30N4O4.3C25H26N4O4.C24H22F2N4O6S.C24H22F2N4O4S/c1-4-28(5-2)9-8-23(18-10-20(30)13-21(31)11-18)35(26(28)38)16-24(36)32-22-7-6-17-14-29(15-19(17)12-22)25(37)33-27(39)34(29)3;1-26(2)12-11-21(17-7-5-4-6-8-17)31(24(26)34)16-22(32)28-20-10-9-18-14-27(15-19(18)13-20)23(33)29-25(35)30(27)3;3*1-28-24(33)27-23(32)25(28)13-17-9-10-19(12-18(17)14-25)26-21(30)15-29-11-5-8-20(22(29)31)16-6-3-2-4-7-16;1-29-23(34)28-22(33)24(29)8-13-2-3-18(6-15(13)9-24)27-20(31)10-30-19(11-37(35,36)12-21(30)32)14-4-16(25)7-17(26)5-14;1-29-23(34)28-22(33)24(29)8-13-2-3-18(6-15(13)9-24)27-20(31)10-30-19(11-35-12-21(30)32)14-4-16(25)7-17(26)5-14/h6-7,10-13,23H,4-5,8-9,14-16H2,1-3H3,(H,32,36)(H,33,37,39);4-10,13,21H,11-12,14-16H2,1-3H3,(H,28,32)(H,29,33,35);3*2-4,6-7,9-10,12,20H,5,8,11,13-15H2,1H3,(H,26,30)(H,27,32,33);2-7,19H,8-12H2,1H3,(H,27,31)(H,28,33,34);2-7,19H,8-12H2,1H3,(H,27,31)(H,28,33,34)/t23-,29-;21-,27-;2*20-,25+;20-,25-;2*19-,24-/m0010100/s1
InChIKeyGCCOIWGSCQWDOK-ZKNGECMISA-N
XLogP16.44
TPSA725.88 Ų
H-Bond Donors14
H-Bond Acceptors31
Rotatable Bonds30
Heavy Atoms245
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003385.73
LogP ≤ 516.44
H-Bond Donors ≤ 514
H-Bond Acceptors ≤ 1031

Analyze 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide with MolForge

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Related Compounds

2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide
CID 25020208
2-[(6S)-6-(3,5-difluorophenyl)-3,3-dimethyl-2-oxopiperidin-1-yl]-N-(1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl)acetamide
CID 25144229
N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide
CID 25020151
2-[(5S)-5-(3,5-difluorophenyl)-2,2-dimethyl-3-oxothiomorpholin-4-yl]-N-(1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl)acetamide
CID 25145494
2-[(6S)-3,3-dimethyl-6-(3-methylthiophen-2-yl)-2-oxopiperidin-1-yl]-N-(1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl)acetamide
CID 25144228
2-[(4aR,9aS)-3-oxo-9,9a-dihydro-4aH-indeno[2,1-b][1,4]oxazin-4-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide;2-[(6R)-6-(3,5-difluorophenyl)-3,3-dimethyl-2-oxopiperazin-1-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide;2-[6-(3,4-difluorophenyl)-3,3-dimethyl-2-oxopiperidin-1-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide;2-[(8R)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(9S)-11-oxo-9-phenyl-6,10-diazaspiro[4.6]undecan-10-yl]acetamide;2-[(9S)-11-oxo-9-phenyl-6,10-diazaspiro[4.6]undecan-10-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide
CID 160967600
2-[(3,5-difluorophenyl)methylamino]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;hydrochloride
CID 173105900
2-[3-chloro-3-(iodomethyl)-2-oxo-5-phenylpiperidin-1-yl]-N-(1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl)acetamide
CID 89323770
2-[3-(1,1-dioxothiolan-3-yl)-2-oxobenzimidazol-1-yl]-N-(1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl)acetamide
CID 10006995
2-[(6S)-6-(2,6-difluorophenyl)-3,3-dimethyl-2-oxopiperidin-1-yl]-N-[(2S)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide
CID 45485692
2-[(6S)-6-(3-chlorophenyl)-3,3-dimethyl-2-oxopiperidin-1-yl]-N-(2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl)acetamide
CID 25145492
2-[(6S)-6-(4-chloro-3-fluorophenyl)-3,3-dimethyl-2-oxopiperidin-1-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide
CID 25020444

Frequently Asked Questions

What is the IUPAC name of 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide?
The IUPAC name of 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide (CID 158211332) is 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide.
What is the SMILES notation for 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide?
The canonical SMILES for 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide is CCC1(CC)CC[C@@H](c2cc(F)cc(F)c2)N(CC(=O)Nc2ccc3c(c2)C[C@@]2(C3)C(=O)NC(=O)N2C)C1=O.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3C(=O)C(C)(C)CC[C@H]3c3ccccc3)cc1C2.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3C(=O)CS(=O)(=O)C[C@H]3c3cc(F)cc(F)c3)cc1C2.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3C(=O)CSC[C@H]3c3cc(F)cc(F)c3)cc1C2.CN1C(=O)NC(=O)[C@@]12Cc1ccc(NC(=O)CN3CCC[C@H](c4ccccc4)C3=O)cc1C2.CN1C(=O)NC(=O)[C@]12Cc1ccc(NC(=O)CN3CCC[C@@H](c4ccccc4)C3=O)cc1C2.CN1C(=O)NC(=O)[C@]12Cc1ccc(NC(=O)CN3CCC[C@H](c4ccccc4)C3=O)cc1C2.
What is the InChIKey of 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide?
The InChIKey is GCCOIWGSCQWDOK-ZKNGECMISA-N. The full InChI is InChI=1S/C29H32F2N4O4.C27H30N4O4.3C25H26N4O4.C24H22F2N4O6S.C24H22F2N4O4S/c1-4-28(5-2)9-8-23(18-10-20(30)13-21(31)11-18)35(26(28)38)16-24(36)32-22-7-6-17-14-29(15-19(17)12-22)25(37)33-27(39)34(29)3;1-26(2)12-11-21(17-7-5-4-6-8-17)31(24(26)34)16-22(32)28-20-10-9-18-14-27(15-19(18)13-20)23(33)29-25(35)30(27)3;3*1-28-24(33)27-23(32)25(28)13-17-9-10-19(12-18(17)14-25)26-21(30)15-29-11-5-8-20(22(29)31)16-6-3-2-4-7-16;1-29-23(34)28-22(33)24(29)8-13-2-3-18(6-15(13)9-24)27-20(31)10-30-19(11-37(35,36)12-21(30)32)14-4-16(25)7-17(26)5-14;1-29-23(34)28-22(33)24(29)8-13-2-3-18(6-15(13)9-24)27-20(31)10-30-19(11-35-12-21(30)32)14-4-16(25)7-17(26)5-14/h6-7,10-13,23H,4-5,8-9,14-16H2,1-3H3,(H,32,36)(H,33,37,39);4-10,13,21H,11-12,14-16H2,1-3H3,(H,28,32)(H,29,33,35);3*2-4,6-7,9-10,12,20H,5,8,11,13-15H2,1H3,(H,26,30)(H,27,32,33);2-7,19H,8-12H2,1H3,(H,27,31)(H,28,33,34);2-7,19H,8-12H2,1H3,(H,27,31)(H,28,33,34)/t23-,29-;21-,27-;2*20-,25+;20-,25-;2*19-,24-/m0010100/s1.
What are the key properties of 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide?
2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide has a molecular weight of 3385.73 g/mol, XLogP of 16.44, 30 rotatable bonds, 14 hydrogen bond donors, and 31 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[(6S)-6-(3,5-difluorophenyl)-3,3-diethyl-2-oxopiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-5-oxothiomorpholin-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(3R)-3-(3,5-difluorophenyl)-1,1,5-trioxo-1,4-thiazinan-4-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;2-[(6S)-3,3-dimethyl-2-oxo-6-phenylpiperidin-1-yl]-N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3S)-2-oxo-3-phenylpiperidin-1-yl]acetamide;N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[(3R)-2-oxo-3-phenylpiperidin-1-yl]acetamide is sourced from PubChem (CID 158211332), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).