6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen

C135H139Cl4F7N26O12S6 — CID 158231280

About 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen

6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen (PubChem CID 158231280) has the molecular formula C135H139Cl4F7N26O12S6 and a molecular weight of 2784.97 g/mol. Its IUPAC name is 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen.

Molecular Properties

• Compound Name: 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen
• PubChem CID: 158231280
• Molecular Formula: C135H139Cl4F7N26O12S6
• Molecular Weight: 2784.97 g/mol
• Exact Mass: 2780.80
• IUPAC Name: 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen
• SMILES: CC(C)NS(=O)(=O)c1cnc(-c2c(C#N)c3ccc(Cl)cc3n2C(C)C)nc1.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(Cl)cc3n2C2CCC2)nc1)C1CC1.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(Cl)cc3n2C2CCCC2)nc1)C1CC1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)NC(CF)CF)cn1)n2C1CCCC1.N#Cc1c(-c2ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn2)n(C2CCC2)c2cc(C3CC3)ccc12.N#Cc1c(-c2ncc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCC2)c2cc(Cl)ccc12.[H][H].[H][H]
• InChI: InChI=1S/C25H23F3N4O2S.C24H25ClN4O2S.C23H23ClN4O2S.C23H24F2N4O2S.C21H20ClF2N5O2S.C19H20ClN5O2S.2H2/c26-25(27,28)24(10-11-24)31-35(33,34)18-7-9-21(30-14-18)23-20(13-29)19-8-6-16(15-4-5-15)12-22(19)32(23)17-2-1-3-17;1-15(16-6-7-16)28-32(30,31)19-9-11-22(27-14-19)24-21(13-26)20-10-8-17(25)12-23(20)29(24)18-4-2-3-5-18;1-14(15-5-6-15)27-31(29,30)18-8-10-21(26-13-18)23-20(12-25)19-9-7-16(24)11-22(19)28(23)17-3-2-4-17;1-15-6-9-22-19(10-15)20(13-26)23(29(22)17-4-2-3-5-17)21-8-7-18(14-27-21)32(30,31)28-16(11-24)12-25;22-13-5-6-17-18(10-25)20(29(19(17)7-13)15-3-1-2-4-15)21-26-11-16(12-27-21)32(30,31)28-14(8-23)9-24;1-11(2)24-28(26,27)14-9-22-19(23-10-14)18-16(8-21)15-6-5-13(20)7-17(15)25(18)12(3)4;;/h6-9,12,14-15,17,31H,1-5,10-11H2;8-12,14-16,18,28H,2-7H2,1H3;7-11,13-15,17,27H,2-6H2,1H3;6-10,14,16-17,28H,2-5,11-12H2,1H3;5-7,11-12,14-15,28H,1-4,8-9H2;5-7,9-12,24H,1-4H3;2*1H/t;15-;14-;;;;;/m.00...../s1
• InChIKey: GEKJCQOMGXIDRT-FHEMNUHDSA-N
• XLogP: 29.29
• TPSA: 552.46 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 32
• Rotatable Bonds: 37
• Heavy Atoms: 190
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2784.97
LogP ≤ 5	29.29
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen?

The IUPAC name of 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen (CID 158231280) is 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen.

What is the SMILES notation for 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen?

The canonical SMILES for 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen is CC(C)NS(=O)(=O)c1cnc(-c2c(C#N)c3ccc(Cl)cc3n2C(C)C)nc1.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(Cl)cc3n2C2CCC2)nc1)C1CC1.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(Cl)cc3n2C2CCCC2)nc1)C1CC1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)NC(CF)CF)cn1)n2C1CCCC1.N#Cc1c(-c2ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn2)n(C2CCC2)c2cc(C3CC3)ccc12.N#Cc1c(-c2ncc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCC2)c2cc(Cl)ccc12.[H][H].[H][H].

What is the InChIKey of 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen?

The InChIKey is GEKJCQOMGXIDRT-FHEMNUHDSA-N. The full InChI is InChI=1S/C25H23F3N4O2S.C24H25ClN4O2S.C23H23ClN4O2S.C23H24F2N4O2S.C21H20ClF2N5O2S.C19H20ClN5O2S.2H2/c26-25(27,28)24(10-11-24)31-35(33,34)18-7-9-21(30-14-18)23-20(13-29)19-8-6-16(15-4-5-15)12-22(19)32(23)17-2-1-3-17;1-15(16-6-7-16)28-32(30,31)19-9-11-22(27-14-19)24-21(13-26)20-10-8-17(25)12-23(20)29(24)18-4-2-3-5-18;1-14(15-5-6-15)27-31(29,30)18-8-10-21(26-13-18)23-20(12-25)19-9-7-16(24)11-22(19)28(23)17-3-2-4-17;1-15-6-9-22-19(10-15)20(13-26)23(29(22)17-4-2-3-5-17)21-8-7-18(14-27-21)32(30,31)28-16(11-24)12-25;22-13-5-6-17-18(10-25)20(29(19(17)7-13)15-3-1-2-4-15)21-26-11-16(12-27-21)32(30,31)28-14(8-23)9-24;1-11(2)24-28(26,27)14-9-22-19(23-10-14)18-16(8-21)15-6-5-13(20)7-17(15)25(18)12(3)4;;/h6-9,12,14-15,17,31H,1-5,10-11H2;8-12,14-16,18,28H,2-7H2,1H3;7-11,13-15,17,27H,2-6H2,1H3;6-10,14,16-17,28H,2-5,11-12H2,1H3;5-7,11-12,14-15,28H,1-4,8-9H2;5-7,9-12,24H,1-4H3;2*1H/t;15-;14-;;;;;/m.00...../s1.

What are the key properties of 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen?

6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen has a molecular weight of 2784.97 g/mol, XLogP of 29.29, 37 rotatable bonds, 6 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(6-chloro-3-cyano-1-cyclobutylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;6-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-[(1S)-1-cyclopropylethyl]pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;2-(6-chloro-3-cyano-1-propan-2-ylindol-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;molecular hydrogen is sourced from PubChem (CID 158231280), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).