6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide

C121H109Cl6F10N31O12S6 — CID 158089575

About 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide

6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide (PubChem CID 158089575) has the molecular formula C121H109Cl6F10N31O12S6 and a molecular weight of 2784.51 g/mol. Its IUPAC name is 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide.

Molecular Properties

• Compound Name: 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide
• PubChem CID: 158089575
• Molecular Formula: C121H109Cl6F10N31O12S6
• Molecular Weight: 2784.51 g/mol
• Exact Mass: 2779.52
• IUPAC Name: 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide
• SMILES: CC(C)NS(=O)(=O)c1cnc(-c2c(C#N)c3cnc(Cl)cc3n2C2CCC2)nc1.CC1(NS(=O)(=O)c2ccc(-c3c(C#N)c4cnc(Cl)cc4n3C3CCC3)nc2)CC1.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cnc(Cl)cc3n2C2CCC2)cc1)C(F)(F)F.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(Cl)ncc12.N#Cc1c(-c2ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn2)n(C2CCC2)c2cc(Cl)ncc12.N#Cc1c(-c2ncc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(Cl)ncc12
• InChI: InChI=1S/C21H17ClF3N5O2S.C21H18ClF3N4O2S.C21H20ClN5O2S.C20H18ClF2N5O2S.C19H17ClF2N6O2S.C19H19ClN6O2S/c22-18-8-17-15(11-28-18)14(9-26)19(30(17)12-2-1-3-12)16-5-4-13(10-27-16)33(31,32)29-20(6-7-20)21(23,24)25;1-12(21(23,24)25)28-32(30,31)15-7-5-13(6-8-15)20-16(10-26)17-11-27-19(22)9-18(17)29(20)14-3-2-4-14;1-21(7-8-21)26-30(28,29)14-5-6-17(24-11-14)20-15(10-23)16-12-25-19(22)9-18(16)27(20)13-3-2-4-13;21-19-6-18-16(11-26-19)15(9-24)20(28(18)13-2-1-3-13)17-5-4-14(10-25-17)31(29,30)27-12(7-22)8-23;20-17-4-16-15(10-24-17)14(7-23)18(28(16)12-2-1-3-12)19-25-8-13(9-26-19)31(29,30)27-11(5-21)6-22;1-11(2)25-29(27,28)13-8-23-19(24-9-13)18-14(7-21)15-10-22-17(20)6-16(15)26(18)12-4-3-5-12/h4-5,8,10-12,29H,1-3,6-7H2;5-9,11-12,14,28H,2-4H2,1H3;5-6,9,11-13,26H,2-4,7-8H2,1H3;4-6,10-13,27H,1-3,7-8H2;4,8-12,27H,1-3,5-6H2;6,8-12,25H,3-5H2,1-2H3/t;12-;;;;/m.0..../s1
• InChIKey: FNXWJVVQDULVKF-DYWLQACDSA-N
• XLogP: 24.78
• TPSA: 616.91 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 37
• Rotatable Bonds: 34
• Heavy Atoms: 186
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2784.51
LogP ≤ 5	24.78
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	37

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide?

The IUPAC name of 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide (CID 158089575) is 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide.

What is the SMILES notation for 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide?

The canonical SMILES for 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide is CC(C)NS(=O)(=O)c1cnc(-c2c(C#N)c3cnc(Cl)cc3n2C2CCC2)nc1.CC1(NS(=O)(=O)c2ccc(-c3c(C#N)c4cnc(Cl)cc4n3C3CCC3)nc2)CC1.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cnc(Cl)cc3n2C2CCC2)cc1)C(F)(F)F.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(Cl)ncc12.N#Cc1c(-c2ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)cn2)n(C2CCC2)c2cc(Cl)ncc12.N#Cc1c(-c2ncc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(Cl)ncc12.

What is the InChIKey of 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide?

The InChIKey is FNXWJVVQDULVKF-DYWLQACDSA-N. The full InChI is InChI=1S/C21H17ClF3N5O2S.C21H18ClF3N4O2S.C21H20ClN5O2S.C20H18ClF2N5O2S.C19H17ClF2N6O2S.C19H19ClN6O2S/c22-18-8-17-15(11-28-18)14(9-26)19(30(17)12-2-1-3-12)16-5-4-13(10-27-16)33(31,32)29-20(6-7-20)21(23,24)25;1-12(21(23,24)25)28-32(30,31)15-7-5-13(6-8-15)20-16(10-26)17-11-27-19(22)9-18(17)29(20)14-3-2-4-14;1-21(7-8-21)26-30(28,29)14-5-6-17(24-11-14)20-15(10-23)16-12-25-19(22)9-18(16)27(20)13-3-2-4-13;21-19-6-18-16(11-26-19)15(9-24)20(28(18)13-2-1-3-13)17-5-4-14(10-25-17)31(29,30)27-12(7-22)8-23;20-17-4-16-15(10-24-17)14(7-23)18(28(16)12-2-1-3-12)19-25-8-13(9-26-19)31(29,30)27-11(5-21)6-22;1-11(2)25-29(27,28)13-8-23-19(24-9-13)18-14(7-21)15-10-22-17(20)6-16(15)26(18)12-4-3-5-12/h4-5,8,10-12,29H,1-3,6-7H2;5-9,11-12,14,28H,2-4H2,1H3;5-6,9,11-13,26H,2-4,7-8H2,1H3;4-6,10-13,27H,1-3,7-8H2;4,8-12,27H,1-3,5-6H2;6,8-12,25H,3-5H2,1-2H3/t;12-;;;;/m.0..../s1.

What are the key properties of 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide?

6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide has a molecular weight of 2784.51 g/mol, XLogP of 24.78, 34 rotatable bonds, 6 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-(1-methylcyclopropyl)pyridine-3-sulfonamide;2-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-propan-2-ylpyrimidine-5-sulfonamide;6-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[1-(trifluoromethyl)cyclopropyl]pyridine-3-sulfonamide;4-(6-chloro-3-cyano-1-cyclobutylpyrrolo[3,2-c]pyridin-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzenesulfonamide is sourced from PubChem (CID 158089575), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).