6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine

C167H130ClF7N20 — CID 158233355

About 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine

6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine (PubChem CID 158233355) has the molecular formula C167H130ClF7N20 and a molecular weight of 2585.46 g/mol. Its IUPAC name is 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine.

Molecular Properties

• Compound Name: 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine
• PubChem CID: 158233355
• Molecular Formula: C167H130ClF7N20
• Molecular Weight: 2585.46 g/mol
• Exact Mass: 2583.04
• IUPAC Name: 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine
• SMILES: Cc1cccc(-c2ccc(CNc3nccc4cc(-c5cccc(Cl)c5)ncc34)cc2)c1.Cc1cccc(-c2ccc(CNc3nccc4cc(-c5cccc(F)c5)ncc34)cc2)c1.Cc1cccc(-c2ccc(CNc3nccc4cc(-c5cccc(F)c5)ncc34)cn2)c1.Cc1cccc(-c2ccc(CNc3nccc4cc(-c5ccccc5)ncc34)cc2)c1.Cc1cccc(-c2ncc(CNc3nccc4cc(-c5cccc(F)c5)ncc34)cc2C)c1.Fc1cccc(-c2cc3ccnc(NCc4ccc(-c5cccc(C(F)(F)F)c5)cc4)c3cn2)c1
• InChI: InChI=1S/C28H22ClN3.C28H19F4N3.C28H23FN4.C28H22FN3.C28H23N3.C27H21FN4/c1-19-4-2-5-22(14-19)21-10-8-20(9-11-21)17-32-28-26-18-31-27(16-23(26)12-13-30-28)24-6-3-7-25(29)15-24;29-24-6-2-4-22(14-24)26-15-21-11-12-33-27(25(21)17-34-26)35-16-18-7-9-19(10-8-18)20-3-1-5-23(13-20)28(30,31)32;1-18-5-3-7-23(11-18)27-19(2)12-20(15-32-27)16-33-28-25-17-31-26(14-21(25)9-10-30-28)22-6-4-8-24(29)13-22;1-19-4-2-5-22(14-19)21-10-8-20(9-11-21)17-32-28-26-18-31-27(16-23(26)12-13-30-28)24-6-3-7-25(29)15-24;1-20-6-5-9-24(16-20)22-12-10-21(11-13-22)18-31-28-26-19-30-27(17-25(26)14-15-29-28)23-7-3-2-4-8-23;1-18-4-2-5-21(12-18)25-9-8-19(15-30-25)16-32-27-24-17-31-26(14-20(24)10-11-29-27)22-6-3-7-23(28)13-22/h2-16,18H,17H2,1H3,(H,30,32);1-15,17H,16H2,(H,33,35);3-15,17H,16H2,1-2H3,(H,30,33);2-16,18H,17H2,1H3,(H,30,32);2-17,19H,18H2,1H3,(H,29,31);2-15,17H,16H2,1H3,(H,29,32)
• InChIKey: GEQQBOHZMYWQDR-UHFFFAOYSA-N
• XLogP: 42.32
• TPSA: 252.64 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 20
• Rotatable Bonds: 30
• Heavy Atoms: 195
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2585.46
LogP ≤ 5	42.32
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine?

The IUPAC name of 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine (CID 158233355) is 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine.

What is the SMILES notation for 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine?

The canonical SMILES for 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine is Cc1cccc(-c2ccc(CNc3nccc4cc(-c5cccc(Cl)c5)ncc34)cc2)c1.Cc1cccc(-c2ccc(CNc3nccc4cc(-c5cccc(F)c5)ncc34)cc2)c1.Cc1cccc(-c2ccc(CNc3nccc4cc(-c5cccc(F)c5)ncc34)cn2)c1.Cc1cccc(-c2ccc(CNc3nccc4cc(-c5ccccc5)ncc34)cc2)c1.Cc1cccc(-c2ncc(CNc3nccc4cc(-c5cccc(F)c5)ncc34)cc2C)c1.Fc1cccc(-c2cc3ccnc(NCc4ccc(-c5cccc(C(F)(F)F)c5)cc4)c3cn2)c1.

What is the InChIKey of 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine?

The InChIKey is GEQQBOHZMYWQDR-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H22ClN3.C28H19F4N3.C28H23FN4.C28H22FN3.C28H23N3.C27H21FN4/c1-19-4-2-5-22(14-19)21-10-8-20(9-11-21)17-32-28-26-18-31-27(16-23(26)12-13-30-28)24-6-3-7-25(29)15-24;29-24-6-2-4-22(14-24)26-15-21-11-12-33-27(25(21)17-34-26)35-16-18-7-9-19(10-8-18)20-3-1-5-23(13-20)28(30,31)32;1-18-5-3-7-23(11-18)27-19(2)12-20(15-32-27)16-33-28-25-17-31-26(14-21(25)9-10-30-28)22-6-4-8-24(29)13-22;1-19-4-2-5-22(14-19)21-10-8-20(9-11-21)17-32-28-26-18-31-27(16-23(26)12-13-30-28)24-6-3-7-25(29)15-24;1-20-6-5-9-24(16-20)22-12-10-21(11-13-22)18-31-28-26-19-30-27(17-25(26)14-15-29-28)23-7-3-2-4-8-23;1-18-4-2-5-21(12-18)25-9-8-19(15-30-25)16-32-27-24-17-31-26(14-20(24)10-11-29-27)22-6-3-7-23(28)13-22/h2-16,18H,17H2,1H3,(H,30,32);1-15,17H,16H2,(H,33,35);3-15,17H,16H2,1-2H3,(H,30,33);2-16,18H,17H2,1H3,(H,30,32);2-17,19H,18H2,1H3,(H,29,31);2-15,17H,16H2,1H3,(H,29,32).

What are the key properties of 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine?

6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine has a molecular weight of 2585.46 g/mol, XLogP of 42.32, 30 rotatable bonds, 6 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-chlorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[5-methyl-6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-(3-methylphenyl)phenyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[6-(3-methylphenyl)-3-pyridinyl]methyl]-2,7-naphthyridin-1-amine;6-(3-fluorophenyl)-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]-2,7-naphthyridin-1-amine;N-[[4-(3-methylphenyl)phenyl]methyl]-6-phenyl-2,7-naphthyridin-1-amine is sourced from PubChem (CID 158233355), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).