N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide

C113H101F5N28O13S4 — CID 158244032

About N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide

N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide (PubChem CID 158244032) has the molecular formula C113H101F5N28O13S4 and a molecular weight of 2282.49 g/mol. Its IUPAC name is N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide.

Molecular Properties

• Compound Name: N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide
• PubChem CID: 158244032
• Molecular Formula: C113H101F5N28O13S4
• Molecular Weight: 2282.49 g/mol
• Exact Mass: 2280.69
• IUPAC Name: N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide
• SMILES: CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(N(C)C)nc(S(C)(=O)=O)c1.CC[C@H](NC(=O)c1nccc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1.CCc1cc([C@H](CC)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)cc(S(C)(=O)=O)n1.CS(=O)(=O)c1cc([C@H](CC#N)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1.O=C(NCc1ccnc2[nH]ccc12)c1cncc2c1cnn2-c1ccc(F)cc1
• InChI: InChI=1S/C24H25FN6O3S.C24H24FN5O3S.C22H17FN6O3S.C22H20FN5O3S.C21H15FN6O/c1-5-20(15-10-22(30(2)3)29-23(11-15)35(4,33)34)28-24(32)19-12-26-14-21-18(19)13-27-31(21)17-8-6-16(25)7-9-17;1-4-17-10-15(11-23(28-17)34(3,32)33)21(5-2)29-24(31)20-12-26-14-22-19(20)13-27-30(22)18-8-6-16(25)7-9-18;1-33(31,32)21-10-14(7-9-26-21)19(6-8-24)28-22(30)18-11-25-13-20-17(18)12-27-29(20)16-4-2-15(23)3-5-16;1-3-18(14-8-10-24-20(12-14)32(2,30)31)27-22(29)21-17-13-26-28(19(17)9-11-25-21)16-6-4-15(23)5-7-16;22-14-1-3-15(4-2-14)28-19-12-23-10-18(17(19)11-27-28)21(29)26-9-13-5-7-24-20-16(13)6-8-25-20/h6-14,20H,5H2,1-4H3,(H,28,32);6-14,21H,4-5H2,1-3H3,(H,29,31);2-5,7,9-13,19H,6H2,1H3,(H,28,30);4-13,18H,3H2,1-2H3,(H,27,29);1-8,10-12H,9H2,(H,24,25)(H,26,29)/t20-;21-;19-;18-;/m0000./s1
• InChIKey: GFXCADUZKPBOIG-QHEKWENASA-N
• XLogP: 16.45
• TPSA: 542.88 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 35
• Rotatable Bonds: 30
• Heavy Atoms: 163
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2282.49
LogP ≤ 5	16.45
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide?

The IUPAC name of N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide (CID 158244032) is N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide.

What is the SMILES notation for N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide?

The canonical SMILES for N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide is CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(N(C)C)nc(S(C)(=O)=O)c1.CC[C@H](NC(=O)c1nccc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1.CCc1cc([C@H](CC)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)cc(S(C)(=O)=O)n1.CS(=O)(=O)c1cc([C@H](CC#N)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1.O=C(NCc1ccnc2[nH]ccc12)c1cncc2c1cnn2-c1ccc(F)cc1.

What is the InChIKey of N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide?

The InChIKey is GFXCADUZKPBOIG-QHEKWENASA-N. The full InChI is InChI=1S/C24H25FN6O3S.C24H24FN5O3S.C22H17FN6O3S.C22H20FN5O3S.C21H15FN6O/c1-5-20(15-10-22(30(2)3)29-23(11-15)35(4,33)34)28-24(32)19-12-26-14-21-18(19)13-27-31(21)17-8-6-16(25)7-9-17;1-4-17-10-15(11-23(28-17)34(3,32)33)21(5-2)29-24(31)20-12-26-14-22-19(20)13-27-30(22)18-8-6-16(25)7-9-18;1-33(31,32)21-10-14(7-9-26-21)19(6-8-24)28-22(30)18-11-25-13-20-17(18)12-27-29(20)16-4-2-15(23)3-5-16;1-3-18(14-8-10-24-20(12-14)32(2,30)31)27-22(29)21-17-13-26-28(19(17)9-11-25-21)16-6-4-15(23)5-7-16;22-14-1-3-15(4-2-14)28-19-12-23-10-18(17(19)11-27-28)21(29)26-9-13-5-7-24-20-16(13)6-8-25-20/h6-14,20H,5H2,1-4H3,(H,28,32);6-14,21H,4-5H2,1-3H3,(H,29,31);2-5,7,9-13,19H,6H2,1H3,(H,28,30);4-13,18H,3H2,1-2H3,(H,27,29);1-8,10-12H,9H2,(H,24,25)(H,26,29)/t20-;21-;19-;18-;/m0000./s1.

What are the key properties of N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide?

N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide has a molecular weight of 2282.49 g/mol, XLogP of 16.45, 30 rotatable bonds, 6 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[2-(dimethylamino)-6-methylsulfonyl-4-pyridinyl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-(2-ethyl-6-methylsulfonyl-4-pyridinyl)propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1S)-1-(2-methylsulfonyl-4-pyridinyl)propyl]pyrazolo[4,5-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide is sourced from PubChem (CID 158244032), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).