2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

C99H119Cl5FN41O7 — CID 158263991

About 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (PubChem CID 158263991) has the molecular formula C99H119Cl5FN41O7 and a molecular weight of 2191.58 g/mol. Its IUPAC name is 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.

Molecular Properties

• Compound Name: 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
• PubChem CID: 158263991
• Molecular Formula: C99H119Cl5FN41O7
• Molecular Weight: 2191.58 g/mol
• Exact Mass: 2187.86
• IUPAC Name: 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
• SMILES: CC(C)N1CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.CN(C)C1CCCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)C1.CN(C)C1CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.CN(C)CC1(O)CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.Nc1nn2cc(F)cnc2c1C(=O)Nc1cncc(Cl)c1N1CCN2CCN(C3COC3)CC2C1
• InChI: InChI=1S/C22H25ClFN9O2.C20H25ClN8O2.3C19H23ClN8O/c23-16-6-26-7-17(28-22(34)18-20(25)29-33-8-13(24)5-27-21(18)33)19(16)32-4-2-30-1-3-31(9-14(30)10-32)15-11-35-12-15;1-27(2)12-20(31)4-7-28(8-5-20)15-3-6-23-10-14(15)25-19(30)16-17(22)26-29-11-13(21)9-24-18(16)29;1-26(2)13-4-7-27(8-5-13)15-3-6-22-10-14(15)24-19(29)16-17(21)25-28-11-12(20)9-23-18(16)28;1-12(2)26-5-7-27(8-6-26)15-3-4-22-10-14(15)24-19(29)16-17(21)25-28-11-13(20)9-23-18(16)28;1-26(2)13-4-3-7-27(11-13)15-5-6-22-9-14(15)24-19(29)16-17(21)25-28-10-12(20)8-23-18(16)28/h5-8,14-15H,1-4,9-12H2,(H2,25,29)(H,28,34);3,6,9-11,31H,4-5,7-8,12H2,1-2H3,(H2,22,26)(H,25,30);3,6,9-11,13H,4-5,7-8H2,1-2H3,(H2,21,25)(H,24,29);3-4,9-12H,5-8H2,1-2H3,(H2,21,25)(H,24,29);5-6,8-10,13H,3-4,7,11H2,1-2H3,(H2,21,25)(H,24,29)
• InChIKey: GIFFKGXHBULCST-UHFFFAOYSA-N
• XLogP: 8.89
• TPSA: 556.10 Ų
• H-Bond Donors: 11
• H-Bond Acceptors: 43
• Rotatable Bonds: 21
• Heavy Atoms: 153
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2191.58
LogP ≤ 5	8.89
H-Bond Donors ≤ 5	11
H-Bond Acceptors ≤ 10	43

Frequently Asked Questions

What is the IUPAC name of 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?

The IUPAC name of 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (CID 158263991) is 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.

What is the SMILES notation for 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?

The canonical SMILES for 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is CC(C)N1CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.CN(C)C1CCCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)C1.CN(C)C1CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.CN(C)CC1(O)CCN(c2ccncc2NC(=O)c2c(N)nn3cc(Cl)cnc23)CC1.Nc1nn2cc(F)cnc2c1C(=O)Nc1cncc(Cl)c1N1CCN2CCN(C3COC3)CC2C1.

What is the InChIKey of 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?

The InChIKey is GIFFKGXHBULCST-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H25ClFN9O2.C20H25ClN8O2.3C19H23ClN8O/c23-16-6-26-7-17(28-22(34)18-20(25)29-33-8-13(24)5-27-21(18)33)19(16)32-4-2-30-1-3-31(9-14(30)10-32)15-11-35-12-15;1-27(2)12-20(31)4-7-28(8-5-20)15-3-6-23-10-14(15)25-19(30)16-17(22)26-29-11-13(21)9-24-18(16)29;1-26(2)13-4-7-27(8-5-13)15-3-6-22-10-14(15)24-19(29)16-17(21)25-28-11-12(20)9-23-18(16)28;1-12(2)26-5-7-27(8-6-26)15-3-4-22-10-14(15)24-19(29)16-17(21)25-28-11-13(20)9-23-18(16)28;1-26(2)13-4-3-7-27(11-13)15-5-6-22-9-14(15)24-19(29)16-17(21)25-28-10-12(20)8-23-18(16)28/h5-8,14-15H,1-4,9-12H2,(H2,25,29)(H,28,34);3,6,9-11,31H,4-5,7-8,12H2,1-2H3,(H2,22,26)(H,25,30);3,6,9-11,13H,4-5,7-8H2,1-2H3,(H2,21,25)(H,24,29);3-4,9-12H,5-8H2,1-2H3,(H2,21,25)(H,24,29);5-6,8-10,13H,3-4,7,11H2,1-2H3,(H2,21,25)(H,24,29).

What are the key properties of 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?

2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide has a molecular weight of 2191.58 g/mol, XLogP of 8.89, 21 rotatable bonds, 11 hydrogen bond donors, and 43 hydrogen bond acceptors.

Where does this data come from?

All data for 2-amino-6-chloro-N-[4-[4-[(dimethylamino)methyl]-4-hydroxypiperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-[4-(dimethylamino)piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-N-[5-chloro-4-[8-(oxetan-3-yl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-2-yl]-3-pyridinyl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide;2-amino-6-chloro-N-[4-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is sourced from PubChem (CID 158263991), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).