5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide

C124H116F12N26O18 — CID 158265804

About 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide

5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide (PubChem CID 158265804) has the molecular formula C124H116F12N26O18 and a molecular weight of 2486.43 g/mol. Its IUPAC name is 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide
• PubChem CID: 158265804
• Molecular Formula: C124H116F12N26O18
• Molecular Weight: 2486.43 g/mol
• Exact Mass: 2484.88
• IUPAC Name: 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide
• SMILES: CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(CCC(F)(F)F)c(-c3cnc(C)c(C(=O)NC(C)(c4ncon4)C4CC4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(CCC(F)(F)F)c(-c3cnc(OC)c(C(=O)NC(C)(C)c4ncon4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cnc(C)c(C(=O)NC(C)(C)c4ncon4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cnc(OC)c(C(=O)NC(C)(C)c4ncon4)c3)cc12
• InChI: InChI=1S/C33H31F3N6O4.C31H29F3N6O5.C30H28F3N7O5.C30H28F3N7O4/c1-17-5-7-19(8-6-17)27-26(29(44)37-4)24-14-23(25(40-30(24)46-27)11-12-33(34,35)36)20-13-22(18(2)38-15-20)28(43)41-32(3,21-9-10-21)31-39-16-45-42-31;1-16-6-8-17(9-7-16)24-23(26(42)35-4)20-13-19(22(38-28(20)45-24)10-11-31(32,33)34)18-12-21(27(43-5)36-14-18)25(41)39-30(2,3)29-37-15-44-40-29;1-15-6-8-16(9-7-15)22-21(25(42)34-4)19-11-18(23(38-27(19)45-22)36-13-30(31,32)33)17-10-20(26(43-5)35-12-17)24(41)39-29(2,3)28-37-14-44-40-28;1-15-6-8-17(9-7-15)23-22(26(42)34-5)21-11-20(24(38-27(21)44-23)36-13-30(31,32)33)18-10-19(16(2)35-12-18)25(41)39-29(3,4)28-37-14-43-40-28/h5-8,13-16,21H,9-12H2,1-4H3,(H,37,44)(H,41,43);6-9,12-15H,10-11H2,1-5H3,(H,35,42)(H,39,41);6-12,14H,13H2,1-5H3,(H,34,42)(H,36,38)(H,39,41);6-12,14H,13H2,1-5H3,(H,34,42)(H,36,38)(H,39,41)
• InChIKey: GIKSKMXAMCOSBM-UHFFFAOYSA-N
• XLogP: 23.05
• TPSA: 586.68 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 36
• Rotatable Bonds: 35
• Heavy Atoms: 180
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2486.43
LogP ≤ 5	23.05
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide?

The IUPAC name of 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide (CID 158265804) is 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide.

What is the SMILES notation for 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide?

The canonical SMILES for 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide is CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(CCC(F)(F)F)c(-c3cnc(C)c(C(=O)NC(C)(c4ncon4)C4CC4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(CCC(F)(F)F)c(-c3cnc(OC)c(C(=O)NC(C)(C)c4ncon4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cnc(C)c(C(=O)NC(C)(C)c4ncon4)c3)cc12.CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(NCC(F)(F)F)c(-c3cnc(OC)c(C(=O)NC(C)(C)c4ncon4)c3)cc12.

What is the InChIKey of 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide?

The InChIKey is GIKSKMXAMCOSBM-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H31F3N6O4.C31H29F3N6O5.C30H28F3N7O5.C30H28F3N7O4/c1-17-5-7-19(8-6-17)27-26(29(44)37-4)24-14-23(25(40-30(24)46-27)11-12-33(34,35)36)20-13-22(18(2)38-15-20)28(43)41-32(3,21-9-10-21)31-39-16-45-42-31;1-16-6-8-17(9-7-16)24-23(26(42)35-4)20-13-19(22(38-28(20)45-24)10-11-31(32,33)34)18-12-21(27(43-5)36-14-18)25(41)39-30(2,3)29-37-15-44-40-29;1-15-6-8-16(9-7-15)22-21(25(42)34-4)19-11-18(23(38-27(19)45-22)36-13-30(31,32)33)17-10-20(26(43-5)35-12-17)24(41)39-29(2,3)28-37-14-44-40-28;1-15-6-8-17(9-7-15)23-22(26(42)34-5)21-11-20(24(38-27(21)44-23)36-13-30(31,32)33)18-10-19(16(2)35-12-18)25(41)39-29(3,4)28-37-14-43-40-28/h5-8,13-16,21H,9-12H2,1-4H3,(H,37,44)(H,41,43);6-9,12-15H,10-11H2,1-5H3,(H,35,42)(H,39,41);6-12,14H,13H2,1-5H3,(H,34,42)(H,36,38)(H,39,41);6-12,14H,13H2,1-5H3,(H,34,42)(H,36,38)(H,39,41).

What are the key properties of 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide?

5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide has a molecular weight of 2486.43 g/mol, XLogP of 23.05, 35 rotatable bonds, 10 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[5-[[1-cyclopropyl-1-(1,2,4-oxadiazol-3-yl)ethyl]carbamoyl]-6-methyl-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide;5-[6-methoxy-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-N-methyl-2-(4-methylphenyl)-6-(3,3,3-trifluoropropyl)furo[2,3-b]pyridine-3-carboxamide;N-methyl-5-[6-methyl-5-[2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamoyl]-3-pyridinyl]-2-(4-methylphenyl)-6-(2,2,2-trifluoroethylamino)furo[2,3-b]pyridine-3-carboxamide is sourced from PubChem (CID 158265804), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).