3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine

C128H148Cl9F6N35OS7 — CID 158312234

About 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine

3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine (PubChem CID 158312234) has the molecular formula C128H148Cl9F6N35OS7 and a molecular weight of 2850.37 g/mol. Its IUPAC name is 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine.

Molecular Properties

• Compound Name: 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine
• PubChem CID: 158312234
• Molecular Formula: C128H148Cl9F6N35OS7
• Molecular Weight: 2850.37 g/mol
• Exact Mass: 2843.78
• IUPAC Name: 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine
• SMILES: CC1CCC12CCN(c1cnc(Sc3cccc(Cl)c3Cl)c(N)n1)CC2.C[C@H]1CCC12CCN(c1cnc(Sc3cccc(N)c3Cl)c(N)n1)CC2.C[C@H]1CCC12CCN(c1cnc(Sc3cccnc3C(F)(F)F)c(N)n1)CC2.C[C@H]1CCC12CCN(c1nc(N)c(Sc3cccnc3C(F)(F)F)nc1C(N)=O)CC2.Nc1nc(N2CC[C@@]3(CC[C@H]3N)C2)cnc1Sc1cccc(Cl)c1Cl.Nc1nc(N2CC[C@]3(CC[C@@H]3N)C2)cnc1Sc1cccc(Cl)c1Cl.Nc1nc(N2CC[C@]3(CC[C@H]3N)C2)cnc1Sc1cccc(Cl)c1Cl
• InChI: InChI=1S/C20H23F3N6OS.C19H22Cl2N4S.C19H24ClN5S.C19H22F3N5S.3C17H19Cl2N5S/c1-11-4-5-19(11)6-9-29(10-7-19)17-13(16(25)30)27-18(15(24)28-17)31-12-3-2-8-26-14(12)20(21,22)23;1-12-5-6-19(12)7-9-25(10-8-19)15-11-23-18(17(22)24-15)26-14-4-2-3-13(20)16(14)21;1-12-5-6-19(12)7-9-25(10-8-19)15-11-23-18(17(22)24-15)26-14-4-2-3-13(21)16(14)20;1-12-4-5-18(12)6-9-27(10-7-18)14-11-25-17(16(23)26-14)28-13-3-2-8-24-15(13)19(20,21)22;3*18-10-2-1-3-11(14(10)19)25-16-15(21)23-13(8-22-16)24-7-6-17(9-24)5-4-12(17)20/h2-3,8,11H,4-7,9-10H2,1H3,(H2,24,28)(H2,25,30);2-4,11-12H,5-10H2,1H3,(H2,22,24);2-4,11-12H,5-10,21H2,1H3,(H2,22,24);2-3,8,11-12H,4-7,9-10H2,1H3,(H2,23,26);3*1-3,8,12H,4-7,9,20H2,(H2,21,23)/t11-;;2*12-;2*12-,17+;12-,17-/m0.00101/s1
• InChIKey: GNUWWZCHZZNQFT-GJLAYEGZSA-N
• XLogP: 29.88
• TPSA: 558.23 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 42
• Rotatable Bonds: 22
• Heavy Atoms: 186
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2850.37
LogP ≤ 5	29.88
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	42

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'aniline', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine?

The IUPAC name of 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine (CID 158312234) is 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine.

What is the SMILES notation for 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine?

The canonical SMILES for 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine is CC1CCC12CCN(c1cnc(Sc3cccc(Cl)c3Cl)c(N)n1)CC2.C[C@H]1CCC12CCN(c1cnc(Sc3cccc(N)c3Cl)c(N)n1)CC2.C[C@H]1CCC12CCN(c1cnc(Sc3cccnc3C(F)(F)F)c(N)n1)CC2.C[C@H]1CCC12CCN(c1nc(N)c(Sc3cccnc3C(F)(F)F)nc1C(N)=O)CC2.Nc1nc(N2CC[C@@]3(CC[C@H]3N)C2)cnc1Sc1cccc(Cl)c1Cl.Nc1nc(N2CC[C@]3(CC[C@@H]3N)C2)cnc1Sc1cccc(Cl)c1Cl.Nc1nc(N2CC[C@]3(CC[C@H]3N)C2)cnc1Sc1cccc(Cl)c1Cl.

What is the InChIKey of 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine?

The InChIKey is GNUWWZCHZZNQFT-GJLAYEGZSA-N. The full InChI is InChI=1S/C20H23F3N6OS.C19H22Cl2N4S.C19H24ClN5S.C19H22F3N5S.3C17H19Cl2N5S/c1-11-4-5-19(11)6-9-29(10-7-19)17-13(16(25)30)27-18(15(24)28-17)31-12-3-2-8-26-14(12)20(21,22)23;1-12-5-6-19(12)7-9-25(10-8-19)15-11-23-18(17(22)24-15)26-14-4-2-3-13(20)16(14)21;1-12-5-6-19(12)7-9-25(10-8-19)15-11-23-18(17(22)24-15)26-14-4-2-3-13(21)16(14)20;1-12-4-5-18(12)6-9-27(10-7-18)14-11-25-17(16(23)26-14)28-13-3-2-8-24-15(13)19(20,21)22;3*18-10-2-1-3-11(14(10)19)25-16-15(21)23-13(8-22-16)24-7-6-17(9-24)5-4-12(17)20/h2-3,8,11H,4-7,9-10H2,1H3,(H2,24,28)(H2,25,30);2-4,11-12H,5-10H2,1H3,(H2,22,24);2-4,11-12H,5-10,21H2,1H3,(H2,22,24);2-3,8,11-12H,4-7,9-10H2,1H3,(H2,23,26);3*1-3,8,12H,4-7,9,20H2,(H2,21,23)/t11-;;2*12-;2*12-,17+;12-,17-/m0.00101/s1.

What are the key properties of 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine?

3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine has a molecular weight of 2850.37 g/mol, XLogP of 29.88, 22 rotatable bonds, 12 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for 3-(3-amino-2-chlorophenyl)sulfanyl-6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]pyrazin-2-amine;(3R,4S)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3S,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;(3R,4R)-6-[6-amino-5-(2,3-dichlorophenyl)sulfanylpyrazin-2-yl]-6-azaspiro[3.4]octan-3-amine;5-amino-3-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-6-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazine-2-carboxamide;3-(2,3-dichlorophenyl)sulfanyl-6-(3-methyl-7-azaspiro[3.5]nonan-7-yl)pyrazin-2-amine;6-[(3S)-3-methyl-7-azaspiro[3.5]nonan-7-yl]-3-[[2-(trifluoromethyl)-3-pyridinyl]sulfanyl]pyrazin-2-amine is sourced from PubChem (CID 158312234), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).