8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one

C67H79Cl4N21O6 — CID 158338143

About 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one

8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one (PubChem CID 158338143) has the molecular formula C67H79Cl4N21O6 and a molecular weight of 1416.32 g/mol. Its IUPAC name is 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one.

Molecular Properties

• Compound Name: 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one
• PubChem CID: 158338143
• Molecular Formula: C67H79Cl4N21O6
• Molecular Weight: 1416.32 g/mol
• Exact Mass: 1413.53
• IUPAC Name: 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one
• SMILES: CC(=O)N1CCOC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C1.CN1CCN(C2CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C1=O.Cn1ccnc1CN1C(=O)NC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C1=O.O=C1NCCN1C1CCN(c2cc(Cl)cc3[nH]ncc23)CC1
• InChI: InChI=1S/C19H20ClN7O2.C17H21ClN4O2.C16H20ClN5O.C15H18ClN5O/c1-25-7-4-21-16(25)11-27-17(28)19(23-18(27)29)2-5-26(6-3-19)15-9-12(20)8-14-13(15)10-22-24-14;1-12(23)22-6-7-24-17(11-22)2-4-21(5-3-17)16-9-13(18)8-15-14(16)10-19-20-15;1-20-6-7-22(16(20)23)12-2-4-21(5-3-12)15-9-11(17)8-14-13(15)10-18-19-14;16-10-7-13-12(9-18-19-13)14(8-10)20-4-1-11(2-5-20)21-6-3-17-15(21)22/h4,7-10H,2-3,5-6,11H2,1H3,(H,22,24)(H,23,29);8-10H,2-7,11H2,1H3,(H,19,20);8-10,12H,2-7H2,1H3,(H,18,19);7-9,11H,1-6H2,(H,17,22)(H,18,19)
• InChIKey: GQVJDCQLVWBUGQ-UHFFFAOYSA-N
• XLogP: 9.24
• TPSA: 280.34 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 16
• Rotatable Bonds: 8
• Heavy Atoms: 98
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1416.32
LogP ≤ 5	9.24
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	16

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one?

The IUPAC name of 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one (CID 158338143) is 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one.

What is the SMILES notation for 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one?

The canonical SMILES for 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one is CC(=O)N1CCOC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C1.CN1CCN(C2CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C1=O.Cn1ccnc1CN1C(=O)NC2(CCN(c3cc(Cl)cc4[nH]ncc34)CC2)C1=O.O=C1NCCN1C1CCN(c2cc(Cl)cc3[nH]ncc23)CC1.

What is the InChIKey of 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one?

The InChIKey is GQVJDCQLVWBUGQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H20ClN7O2.C17H21ClN4O2.C16H20ClN5O.C15H18ClN5O/c1-25-7-4-21-16(25)11-27-17(28)19(23-18(27)29)2-5-26(6-3-19)15-9-12(20)8-14-13(15)10-22-24-14;1-12(23)22-6-7-24-17(11-22)2-4-21(5-3-17)16-9-13(18)8-15-14(16)10-19-20-15;1-20-6-7-22(16(20)23)12-2-4-21(5-3-12)15-9-11(17)8-14-13(15)10-18-19-14;16-10-7-13-12(9-18-19-13)14(8-10)20-4-1-11(2-5-20)21-6-3-17-15(21)22/h4,7-10H,2-3,5-6,11H2,1H3,(H,22,24)(H,23,29);8-10H,2-7,11H2,1H3,(H,19,20);8-10,12H,2-7H2,1H3,(H,18,19);7-9,11H,1-6H2,(H,17,22)(H,18,19).

What are the key properties of 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one?

8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one has a molecular weight of 1416.32 g/mol, XLogP of 9.24, 8 rotatable bonds, 6 hydrogen bond donors, and 16 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(6-chloro-1H-indazol-4-yl)-3-[(1-methylimidazol-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione;1-[9-(6-chloro-1H-indazol-4-yl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]ethanone;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]imidazolidin-2-one;1-[1-(6-chloro-1H-indazol-4-yl)piperidin-4-yl]-3-methylimidazolidin-2-one is sourced from PubChem (CID 158338143), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).