4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one

C228H297N41O12 — CID 158373396

IUPAC4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccccn1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1cccnc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccnc(N3CCCCC3)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccnc(N3CCNCC3)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccnc(N3CCOCC3)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccncc1)C(=O)N2.CN1CCN(c2cc(CN3CC4(CCC(c5ccccc5)(N(C)C)CC4)NC3=O)ccn2)CC1.COc1ccccc1CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(Cc2ccc(C#N)cc2)C1=O.COc1ccccc1CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O
InChIInChI=1S/C32H36N4O2.C27H38N6O.C27H37N5O.C26H36N6O.C26H35N5O2.C24H31N3O2.3C22H28N4O/c1-34(2)32(28-10-5-4-6-11-28)19-17-31(18-20-32)24-35(23-27-9-7-8-12-29(27)38-3)30(37)36(31)22-26-15-13-25(21-33)14-16-26;1-30(2)27(23-7-5-4-6-8-23)12-10-26(11-13-27)21-33(25(34)29-26)20-22-9-14-28-24(19-22)32-17-15-31(3)16-18-32;1-30(2)27(23-9-5-3-6-10-23)14-12-26(13-15-27)21-32(25(33)29-26)20-22-11-16-28-24(19-22)31-17-7-4-8-18-31;1-30(2)26(22-6-4-3-5-7-22)11-9-25(10-12-26)20-32(24(33)29-25)19-21-8-13-28-23(18-21)31-16-14-27-15-17-31;1-29(2)26(22-6-4-3-5-7-22)11-9-25(10-12-26)20-31(24(32)28-25)19-21-8-13-27-23(18-21)30-14-16-33-17-15-30;1-26(2)24(20-10-5-4-6-11-20)15-13-23(14-16-24)18-27(22(28)25-23)17-19-9-7-8-12-21(19)29-3;1-25(2)22(19-8-4-3-5-9-19)12-10-21(11-13-22)17-26(20(27)24-21)16-18-7-6-14-23-15-18;1-25(2)22(18-8-4-3-5-9-18)13-11-21(12-14-22)17-26(20(27)24-21)16-19-10-6-7-15-23-19;1-25(2)22(19-6-4-3-5-7-19)12-10-21(11-13-22)17-26(20(27)24-21)16-18-8-14-23-15-9-18/h4-16H,17-20,22-24H2,1-3H3;4-9,14,19H,10-13,15-18,20-21H2,1-3H3,(H,29,34);3,5-6,9-11,16,19H,4,7-8,12-15,17-18,20-21H2,1-2H3,(H,29,33);3-8,13,18,27H,9-12,14-17,19-20H2,1-2H3,(H,29,33);3-8,13,18H,9-12,14-17,19-20H2,1-2H3,(H,28,32);4-12H,13-18H2,1-3H3,(H,25,28);3-9,14-15H,10-13,16-17H2,1-2H3,(H,24,27);3-10,15H,11-14,16-17H2,1-2H3,(H,24,27);3-9,14-15H,10-13,16-17H2,1-2H3,(H,24,27)
InChIKeyGUWYSEXCKDDXPJ-UHFFFAOYSA-N
MW3804.16 g/mol
LogP33.39
Rot. Bonds44

About 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one

4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 158373396) has the molecular formula C228H297N41O12 and a molecular weight of 3804.16 g/mol. Its IUPAC name is 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

Compound Name4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one
PubChem CID158373396
Molecular FormulaC228H297N41O12
Molecular Weight3804.16 g/mol
Exact Mass3801.39
IUPAC Name4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccccn1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1cccnc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccnc(N3CCCCC3)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccnc(N3CCNCC3)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccnc(N3CCOCC3)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccncc1)C(=O)N2.CN1CCN(c2cc(CN3CC4(CCC(c5ccccc5)(N(C)C)CC4)NC3=O)ccn2)CC1.COc1ccccc1CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(Cc2ccc(C#N)cc2)C1=O.COc1ccccc1CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O
InChIInChI=1S/C32H36N4O2.C27H38N6O.C27H37N5O.C26H36N6O.C26H35N5O2.C24H31N3O2.3C22H28N4O/c1-34(2)32(28-10-5-4-6-11-28)19-17-31(18-20-32)24-35(23-27-9-7-8-12-29(27)38-3)30(37)36(31)22-26-15-13-25(21-33)14-16-26;1-30(2)27(23-7-5-4-6-8-23)12-10-26(11-13-27)21-33(25(34)29-26)20-22-9-14-28-24(19-22)32-17-15-31(3)16-18-32;1-30(2)27(23-9-5-3-6-10-23)14-12-26(13-15-27)21-32(25(33)29-26)20-22-11-16-28-24(19-22)31-17-7-4-8-18-31;1-30(2)26(22-6-4-3-5-7-22)11-9-25(10-12-26)20-32(24(33)29-25)19-21-8-13-28-23(18-21)31-16-14-27-15-17-31;1-29(2)26(22-6-4-3-5-7-22)11-9-25(10-12-26)20-31(24(32)28-25)19-21-8-13-27-23(18-21)30-14-16-33-17-15-30;1-26(2)24(20-10-5-4-6-11-20)15-13-23(14-16-24)18-27(22(28)25-23)17-19-9-7-8-12-21(19)29-3;1-25(2)22(19-8-4-3-5-9-19)12-10-21(11-13-22)17-26(20(27)24-21)16-18-7-6-14-23-15-18;1-25(2)22(18-8-4-3-5-9-18)13-11-21(12-14-22)17-26(20(27)24-21)16-19-10-6-7-15-23-19;1-25(2)22(19-6-4-3-5-7-19)12-10-21(11-13-22)17-26(20(27)24-21)16-18-8-14-23-15-9-18/h4-16H,17-20,22-24H2,1-3H3;4-9,14,19H,10-13,15-18,20-21H2,1-3H3,(H,29,34);3,5-6,9-11,16,19H,4,7-8,12-15,17-18,20-21H2,1-2H3,(H,29,33);3-8,13,18,27H,9-12,14-17,19-20H2,1-2H3,(H,29,33);3-8,13,18H,9-12,14-17,19-20H2,1-2H3,(H,28,32);4-12H,13-18H2,1-3H3,(H,25,28);3-9,14-15H,10-13,16-17H2,1-2H3,(H,24,27);3-10,15H,11-14,16-17H2,1-2H3,(H,24,27);3-9,14-15H,10-13,16-17H2,1-2H3,(H,24,27)
InChIKeyGUWYSEXCKDDXPJ-UHFFFAOYSA-N
XLogP33.39
TPSA481.37 Ų
H-Bond Donors9
H-Bond Acceptors35
Rotatable Bonds44
Heavy Atoms281
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003804.16
LogP ≤ 533.39
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1035

Analyze 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one with MolForge

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Related Compounds

8-(Dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(2-methoxyphenyl)methyl]-3-(2-methylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-methylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-2-carbonitrile;8-(dimethylamino)-8-phenyl-3-[6-(trifluoromethyl)-3-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one;2-[1-(3-methoxypropyl)-8-(methylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-5-carbonitrile
CID 157121317
8-(Dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one
CID 158131395
8-(Dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one
CID 158819720
8-(Dimethylamino)-1-[(1-hydroxycyclobutyl)methyl]-3-(2-methylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-1-[(2-methoxyphenyl)methyl]-3-(2-methylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-methylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-methylpyrimidin-5-yl)-8-phenyl-1-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(2-morpholin-4-ylpyrimidin-5-yl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-4-methylpyridine-2-carbonitrile;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-8-phenyl-3-pyrimidin-5-yl-1,3-diazaspiro[4.5]decan-2-one;1-[(1-hydroxycyclobutyl)methyl]-8-(methylamino)-8-phenyl-3-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-diazaspiro[4.5]decan-2-one
CID 159215817
CID 160731578
CID 160731578
CID 161310473
CID 161310473
CID 161692053
CID 161692053
4-[1-[2-[(5S)-2-[4-amino-3-(4-methylpyridine-3-carboximidoyl)phenyl]-1-oxo-2,7-diazaspiro[4.4]nonan-7-yl]acetyl]-3,6-dihydro-2H-pyridin-4-yl]-N'-(methyliminomethyl)benzenecarboximidamide;4-[1-[2-[(5S)-2-[4-amino-3-(6-methylpyridine-3-carboximidoyl)phenyl]-1-oxo-2,7-diazaspiro[4.4]nonan-7-yl]acetyl]-3,6-dihydro-2H-pyridin-4-yl]-N'-(methyliminomethyl)benzenecarboximidamide;4-[4-[2-[(5S)-2-[4-amino-3-(6-propan-2-yloxypyridine-3-carboximidoyl)phenyl]-1-oxo-2,7-diazaspiro[4.4]nonan-7-yl]acetyl]piperazin-1-yl]-N'-(methyliminomethyl)benzenecarboximidamide;6-[4-[2-[(5S)-2-[4-amino-3-(6-propan-2-yloxypyridine-3-carboximidoyl)phenyl]-1-oxo-2,7-diazaspiro[4.4]nonan-7-yl]acetyl]piperazin-1-yl]-N'-(methyliminomethyl)pyridine-3-carboximidamide
CID 158629010
2-cyclopentyloxy-5-[2-(4-morpholin-4-ylphenyl)-1H-imidazo[4,5-b]pyridin-7-yl]benzonitrile;2-[(3R)-1-(2-isocyanoacetyl)pyrrolidin-3-yl]oxy-5-[2-(4-morpholin-4-ylphenyl)-1H-imidazo[4,5-b]pyridin-7-yl]benzonitrile;5-[2-(4-morpholin-4-ylphenyl)-1H-imidazo[4,5-b]pyridin-7-yl]-2-[(3R)-pyrrolidin-3-yl]oxybenzonitrile
CID 158655065
1-[(4-aminophenyl)methyl]-3-[2-oxo-2-[(2R)-2-pyridin-3-ylpyrrolidin-1-yl]ethyl]urea;1-[(6-amino-3-pyridinyl)methyl]-3-[2-(1,2-oxazolidin-2-yl)-2-oxoethyl]urea;1-[(6-amino-3-pyridinyl)methyl]-3-[2-oxo-2-(2-pyridin-2-ylpyrrolidin-1-yl)ethyl]urea;1-[2-[2-(2-methoxyphenyl)pyrrolidin-1-yl]-2-oxoethyl]-3-[(6-methyl-3-pyridinyl)methyl]urea
CID 158758431
3-[2-(4-acetylpiperazin-1-yl)pyrimidin-5-yl]-8-(dimethylamino)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[2-(4-methylpiperazine-1-carbonyl)pyrimidin-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-N-(2-hydroxyethyl)pyrimidine-2-carboxamide;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyrimidine-2-carboxamide;8-(dimethylamino)-8-phenyl-3-(2-pyridin-3-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(2-pyridin-4-ylpyrimidin-5-yl)-1,3-diazaspiro[4.5]decan-2-one;bis(4-[8-(ethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]-3-methoxybenzonitrile)
CID 159282878
1-[5-[3-cyano-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl]-2-pyridinyl]-N-(2-methoxy-3-methylbutyl)piperidine-4-carboxamide;4-[6-[4-[(2,6-difluorophenyl)methyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[2-(4-fluorophenyl)acetyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile;4-[6-[4-[(2-methoxyphenyl)methyl]piperazin-1-yl]-3-pyridinyl]-6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
CID 159663335

Frequently Asked Questions

What is the IUPAC name of 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one?
The IUPAC name of 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one (CID 158373396) is 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one.
What is the SMILES notation for 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one?
The canonical SMILES for 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one is CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccccn1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1cccnc1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccnc(N3CCCCC3)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccnc(N3CCNCC3)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccnc(N3CCOCC3)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1ccncc1)C(=O)N2.CN1CCN(c2cc(CN3CC4(CCC(c5ccccc5)(N(C)C)CC4)NC3=O)ccn2)CC1.COc1ccccc1CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)N(Cc2ccc(C#N)cc2)C1=O.COc1ccccc1CN1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.
What is the InChIKey of 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one?
The InChIKey is GUWYSEXCKDDXPJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C32H36N4O2.C27H38N6O.C27H37N5O.C26H36N6O.C26H35N5O2.C24H31N3O2.3C22H28N4O/c1-34(2)32(28-10-5-4-6-11-28)19-17-31(18-20-32)24-35(23-27-9-7-8-12-29(27)38-3)30(37)36(31)22-26-15-13-25(21-33)14-16-26;1-30(2)27(23-7-5-4-6-8-23)12-10-26(11-13-27)21-33(25(34)29-26)20-22-9-14-28-24(19-22)32-17-15-31(3)16-18-32;1-30(2)27(23-9-5-3-6-10-23)14-12-26(13-15-27)21-32(25(33)29-26)20-22-11-16-28-24(19-22)31-17-7-4-8-18-31;1-30(2)26(22-6-4-3-5-7-22)11-9-25(10-12-26)20-32(24(33)29-25)19-21-8-13-28-23(18-21)31-16-14-27-15-17-31;1-29(2)26(22-6-4-3-5-7-22)11-9-25(10-12-26)20-31(24(32)28-25)19-21-8-13-27-23(18-21)30-14-16-33-17-15-30;1-26(2)24(20-10-5-4-6-11-20)15-13-23(14-16-24)18-27(22(28)25-23)17-19-9-7-8-12-21(19)29-3;1-25(2)22(19-8-4-3-5-9-19)12-10-21(11-13-22)17-26(20(27)24-21)16-18-7-6-14-23-15-18;1-25(2)22(18-8-4-3-5-9-18)13-11-21(12-14-22)17-26(20(27)24-21)16-19-10-6-7-15-23-19;1-25(2)22(19-6-4-3-5-7-19)12-10-21(11-13-22)17-26(20(27)24-21)16-18-8-14-23-15-9-18/h4-16H,17-20,22-24H2,1-3H3;4-9,14,19H,10-13,15-18,20-21H2,1-3H3,(H,29,34);3,5-6,9-11,16,19H,4,7-8,12-15,17-18,20-21H2,1-2H3,(H,29,33);3-8,13,18,27H,9-12,14-17,19-20H2,1-2H3,(H,29,33);3-8,13,18H,9-12,14-17,19-20H2,1-2H3,(H,28,32);4-12H,13-18H2,1-3H3,(H,25,28);3-9,14-15H,10-13,16-17H2,1-2H3,(H,24,27);3-10,15H,11-14,16-17H2,1-2H3,(H,24,27);3-9,14-15H,10-13,16-17H2,1-2H3,(H,24,27).
What are the key properties of 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one?
4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 3804.16 g/mol, XLogP of 33.39, 44 rotatable bonds, 9 hydrogen bond donors, and 35 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[[8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]methyl]benzonitrile;8-(dimethylamino)-3-[(2-methoxyphenyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[[2-(4-methylpiperazin-1-yl)-4-pyridinyl]methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(2-morpholin-4-yl-4-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperazin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[(2-piperidin-1-yl-4-pyridinyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-2-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-(pyridin-4-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 158373396), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).