8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one

C111H132F6N20O6 — CID 158819720

About 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one

8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 158819720) has the molecular formula C111H132F6N20O6 and a molecular weight of 1956.40 g/mol. Its IUPAC name is 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

• Compound Name: 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one
• PubChem CID: 158819720
• Molecular Formula: C111H132F6N20O6
• Molecular Weight: 1956.40 g/mol
• Exact Mass: 1955.05
• IUPAC Name: 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one
• SMILES: CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C(F)(F)F)cn1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cccc(C(F)(F)F)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cncc(C#N)c1)C(=O)N2.COc1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.Cc1cccnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O
• InChI: InChI=1S/C23H26F3N3O.C22H25F3N4O.C22H25N5O.C22H28N4O2.C22H28N4O/c1-28(2)22(17-7-4-3-5-8-17)13-11-21(12-14-22)16-29(20(30)27-21)19-10-6-9-18(15-19)23(24,25)26;1-28(2)21(16-6-4-3-5-7-16)12-10-20(11-13-21)15-29(19(30)27-20)18-9-8-17(14-26-18)22(23,24)25;1-26(2)22(18-6-4-3-5-7-18)10-8-21(9-11-22)16-27(20(28)25-21)19-12-17(13-23)14-24-15-19;1-25(2)22(17-7-5-4-6-8-17)13-11-21(12-14-22)16-26(20(27)24-21)18-9-10-19(28-3)23-15-18;1-17-8-7-15-23-19(17)26-16-21(24-20(26)27)11-13-22(14-12-21,25(2)3)18-9-5-4-6-10-18/h3-10,15H,11-14,16H2,1-2H3,(H,27,30);3-9,14H,10-13,15H2,1-2H3,(H,27,30);3-7,12,14-15H,8-11,16H2,1-2H3,(H,25,28);4-10,15H,11-14,16H2,1-3H3,(H,24,27);4-10,15H,11-14,16H2,1-3H3,(H,24,27)
• InChIKey: IVSCMAKWWPYNTO-UHFFFAOYSA-N
• XLogP: 19.74
• TPSA: 262.48 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 16
• Rotatable Bonds: 16
• Heavy Atoms: 143
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1956.40
LogP ≤ 5	19.74
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	16

Frequently Asked Questions

What is the IUPAC name of 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one?

The IUPAC name of 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one (CID 158819720) is 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one.

What is the SMILES notation for 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one?

The canonical SMILES for 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one is CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1ccc(C(F)(F)F)cn1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cccc(C(F)(F)F)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cncc(C#N)c1)C(=O)N2.COc1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.Cc1cccnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.

What is the InChIKey of 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one?

The InChIKey is IVSCMAKWWPYNTO-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H26F3N3O.C22H25F3N4O.C22H25N5O.C22H28N4O2.C22H28N4O/c1-28(2)22(17-7-4-3-5-8-17)13-11-21(12-14-22)16-29(20(30)27-21)19-10-6-9-18(15-19)23(24,25)26;1-28(2)21(16-6-4-3-5-7-16)12-10-20(11-13-21)15-29(19(30)27-20)18-9-8-17(14-26-18)22(23,24)25;1-26(2)22(18-6-4-3-5-7-18)10-8-21(9-11-22)16-27(20(28)25-21)19-12-17(13-23)14-24-15-19;1-25(2)22(17-7-5-4-6-8-17)13-11-21(12-14-22)16-26(20(27)24-21)18-9-10-19(28-3)23-15-18;1-17-8-7-15-23-19(17)26-16-21(24-20(26)27)11-13-22(14-12-21,25(2)3)18-9-5-4-6-10-18/h3-10,15H,11-14,16H2,1-2H3,(H,27,30);3-9,14H,10-13,15H2,1-2H3,(H,27,30);3-7,12,14-15H,8-11,16H2,1-2H3,(H,25,28);4-10,15H,11-14,16H2,1-3H3,(H,24,27);4-10,15H,11-14,16H2,1-3H3,(H,24,27).

What are the key properties of 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one?

8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 1956.40 g/mol, XLogP of 19.74, 16 rotatable bonds, 5 hydrogen bond donors, and 16 hydrogen bond acceptors.

Where does this data come from?

All data for 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 158819720), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).