8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one

C89H107F3N16O5 — CID 159300216

IUPAC8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cccc(C(F)(F)F)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cncc(C#N)c1)C(=O)N2.COc1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.Cc1cccnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O
InChIInChI=1S/C23H26F3N3O.C22H25N5O.C22H28N4O2.C22H28N4O/c1-28(2)22(17-7-4-3-5-8-17)13-11-21(12-14-22)16-29(20(30)27-21)19-10-6-9-18(15-19)23(24,25)26;1-26(2)22(18-6-4-3-5-7-18)10-8-21(9-11-22)16-27(20(28)25-21)19-12-17(13-23)14-24-15-19;1-25(2)22(17-7-5-4-6-8-17)13-11-21(12-14-22)16-26(20(27)24-21)18-9-10-19(28-3)23-15-18;1-17-8-7-15-23-19(17)26-16-21(24-20(26)27)11-13-22(14-12-21,25(2)3)18-9-5-4-6-10-18/h3-10,15H,11-14,16H2,1-2H3,(H,27,30);3-7,12,14-15H,8-11,16H2,1-2H3,(H,25,28);4-10,15H,11-14,16H2,1-3H3,(H,24,27);4-10,15H,11-14,16H2,1-3H3,(H,24,27)
InChIKeyLBFVGFPYZRNFGJ-UHFFFAOYSA-N
MW1537.94 g/mol
LogP15.34
Rot. Bonds13

About 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one

8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 159300216) has the molecular formula C89H107F3N16O5 and a molecular weight of 1537.94 g/mol. Its IUPAC name is 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

Compound Name8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one
PubChem CID159300216
Molecular FormulaC89H107F3N16O5
Molecular Weight1537.94 g/mol
Exact Mass1536.86
IUPAC Name8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cccc(C(F)(F)F)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cncc(C#N)c1)C(=O)N2.COc1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.Cc1cccnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O
InChIInChI=1S/C23H26F3N3O.C22H25N5O.C22H28N4O2.C22H28N4O/c1-28(2)22(17-7-4-3-5-8-17)13-11-21(12-14-22)16-29(20(30)27-21)19-10-6-9-18(15-19)23(24,25)26;1-26(2)22(18-6-4-3-5-7-18)10-8-21(9-11-22)16-27(20(28)25-21)19-12-17(13-23)14-24-15-19;1-25(2)22(17-7-5-4-6-8-17)13-11-21(12-14-22)16-26(20(27)24-21)18-9-10-19(28-3)23-15-18;1-17-8-7-15-23-19(17)26-16-21(24-20(26)27)11-13-22(14-12-21,25(2)3)18-9-5-4-6-10-18/h3-10,15H,11-14,16H2,1-2H3,(H,27,30);3-7,12,14-15H,8-11,16H2,1-2H3,(H,25,28);4-10,15H,11-14,16H2,1-3H3,(H,24,27);4-10,15H,11-14,16H2,1-3H3,(H,24,27)
InChIKeyLBFVGFPYZRNFGJ-UHFFFAOYSA-N
XLogP15.34
TPSA214.01 Ų
H-Bond Donors4
H-Bond Acceptors13
Rotatable Bonds13
Heavy Atoms113
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001537.94
LogP ≤ 515.34
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1013

Analyze 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one with MolForge

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Related Compounds

6-[5-(Cyclopropylmethyl)-2-(dimethylamino)-2-(3-fluorophenyl)-6-oxo-5,7-diazaspiro[3.4]octan-7-yl]-5-methylpyridine-3-carbonitrile;5-(cyclopropylmethyl)-2-(dimethylamino)-2-(3-fluorophenyl)-7-[5-(trifluoromethoxy)-2-pyridinyl]-5,7-diazaspiro[3.4]octan-6-one;2-(dimethylamino)-2-(3-fluorophenyl)-7-[5-(trifluoromethoxy)-2-pyridinyl]-5,7-diazaspiro[3.4]octan-6-one;2-(dimethylamino)-7-(4-methyl-6-morpholin-4-yl-3-pyridinyl)-2-phenyl-5,7-diazaspiro[3.4]octan-6-one
CID 157770022
8-(Dimethylamino)-3-(6-methoxy-4-methyl-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methoxy-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one
CID 158131395
8-(Dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-phenyl-3-[5-(trifluoromethyl)-2-pyridinyl]-1,3-diazaspiro[4.5]decan-2-one
CID 158819720
5-[5-(Cyclopropylmethyl)-2-(dimethylamino)-2-(3-fluorophenyl)-6-oxo-5,7-diazaspiro[3.4]octan-7-yl]-4-methylpyridine-2-carbonitrile;5-(cyclopropylmethyl)-2-(dimethylamino)-2-(3-fluorophenyl)-7-[5-(trifluoromethoxy)-2-pyridinyl]-5,7-diazaspiro[3.4]octan-6-one;2-(dimethylamino)-2-(3-fluorophenyl)-7-[5-(trifluoromethoxy)-2-pyridinyl]-5,7-diazaspiro[3.4]octan-6-one
CID 159412325

Frequently Asked Questions

What is the IUPAC name of 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one?
The IUPAC name of 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one (CID 159300216) is 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one.
What is the SMILES notation for 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one?
The canonical SMILES for 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one is CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cccc(C(F)(F)F)c1)C(=O)N2.CN(C)C1(c2ccccc2)CCC2(CC1)CN(c1cncc(C#N)c1)C(=O)N2.COc1ccc(N2CC3(CCC(c4ccccc4)(N(C)C)CC3)NC2=O)cn1.Cc1cccnc1N1CC2(CCC(c3ccccc3)(N(C)C)CC2)NC1=O.
What is the InChIKey of 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one?
The InChIKey is LBFVGFPYZRNFGJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H26F3N3O.C22H25N5O.C22H28N4O2.C22H28N4O/c1-28(2)22(17-7-4-3-5-8-17)13-11-21(12-14-22)16-29(20(30)27-21)19-10-6-9-18(15-19)23(24,25)26;1-26(2)22(18-6-4-3-5-7-18)10-8-21(9-11-22)16-27(20(28)25-21)19-12-17(13-23)14-24-15-19;1-25(2)22(17-7-5-4-6-8-17)13-11-21(12-14-22)16-26(20(27)24-21)18-9-10-19(28-3)23-15-18;1-17-8-7-15-23-19(17)26-16-21(24-20(26)27)11-13-22(14-12-21,25(2)3)18-9-5-4-6-10-18/h3-10,15H,11-14,16H2,1-2H3,(H,27,30);3-7,12,14-15H,8-11,16H2,1-2H3,(H,25,28);4-10,15H,11-14,16H2,1-3H3,(H,24,27);4-10,15H,11-14,16H2,1-3H3,(H,24,27).
What are the key properties of 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one?
8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 1537.94 g/mol, XLogP of 15.34, 13 rotatable bonds, 4 hydrogen bond donors, and 13 hydrogen bond acceptors.
Where does this data come from?
All data for 8-(dimethylamino)-3-(6-methoxy-3-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-(3-methyl-2-pyridinyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;5-[8-(dimethylamino)-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-3-yl]pyridine-3-carbonitrile;8-(dimethylamino)-8-phenyl-3-[3-(trifluoromethyl)phenyl]-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 159300216), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).