5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide

C142H143ClF22N24O19S12 — CID 158435959

About 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide

5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide (PubChem CID 158435959) has the molecular formula C142H143ClF22N24O19S12 and a molecular weight of 3328.07 g/mol. Its IUPAC name is 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide.

Molecular Properties

• Compound Name: 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide
• PubChem CID: 158435959
• Molecular Formula: C142H143ClF22N24O19S12
• Molecular Weight: 3328.07 g/mol
• Exact Mass: 3324.69
• IUPAC Name: 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide
• SMILES: Cc1cc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4ncns4)ccc32)n(C)n1.Cn1ccc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4ncns4)ccc32)n1.NC(=O)c1cccc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4ncns4)ccc32)c1.Nc1cccc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4nccs4)c(F)cc32)n1.O=S(=O)(Cc1ncns1)c1ccc2c(c1)OCC[C@@H]2N1CC[C@@H](C(F)(F)F)C[C@H]1c1ccc(F)c(Cl)c1.O=S(=O)(Nc1nccs1)c1cc2c(cc1F)[C@@H](N1CC[C@@H](C(F)(F)F)C[C@H]1c1ccc(F)cc1)CCO2
• InChI: InChI=1S/C25H25F3N4O4S2.C24H22ClF4N3O3S2.C24H22F5N3O3S2.C24H24F4N4O3S2.C23H26F3N5O3S2.C22H24F3N5O3S2/c26-25(27,28)17-6-8-32(21(11-17)15-2-1-3-16(10-15)24(29)33)20-7-9-36-22-12-18(4-5-19(20)22)38(34,35)13-23-30-14-31-37-23;25-18-9-14(1-4-19(18)26)21-10-15(24(27,28)29)5-7-32(21)20-6-8-35-22-11-16(2-3-17(20)22)37(33,34)12-23-30-13-31-36-23;25-16-3-1-14(2-4-16)20-11-15(24(27,28)29)5-8-32(20)19-6-9-35-21-13-22(18(26)12-17(19)21)37(33,34)31-23-30-7-10-36-23;25-16-11-15-18(5-8-35-20(15)12-21(16)37(33,34)13-23-30-6-9-36-23)32-7-4-14(24(26,27)28)10-19(32)17-2-1-3-22(29)31-17;1-14-9-19(30(2)29-14)20-10-15(23(24,25)26)5-7-31(20)18-6-8-34-21-11-16(3-4-17(18)21)36(32,33)12-22-27-13-28-35-22;1-29-7-5-17(28-29)19-10-14(22(23,24)25)4-8-30(19)18-6-9-33-20-11-15(2-3-16(18)20)35(31,32)12-21-26-13-27-34-21/h1-5,10,12,14,17,20-21H,6-9,11,13H2,(H2,29,33);1-4,9,11,13,15,20-21H,5-8,10,12H2;1-4,7,10,12-13,15,19-20H,5-6,8-9,11H2,(H,30,31);1-3,6,9,11-12,14,18-19H,4-5,7-8,10,13H2,(H2,29,31);3-4,9,11,13,15,18,20H,5-8,10,12H2,1-2H3;2-3,5,7,11,13-14,18-19H,4,6,8-10,12H2,1H3/t17-,20+,21+;15-,20+,21+;15-,19+,20+;14-,18+,19+;15-,18+,20+;14-,18+,19+/m111111/s1
• InChIKey: HCFLSJKAUGDKBA-BFORGLBKSA-N
• XLogP: 30.21
• TPSA: 538.23 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 47
• Rotatable Bonds: 31
• Heavy Atoms: 220
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	3328.07
LogP ≤ 5	30.21
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	47

Frequently Asked Questions

What is the IUPAC name of 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide?

The IUPAC name of 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide (CID 158435959) is 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide.

What is the SMILES notation for 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide?

The canonical SMILES for 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide is Cc1cc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4ncns4)ccc32)n(C)n1.Cn1ccc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4ncns4)ccc32)n1.NC(=O)c1cccc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4ncns4)ccc32)c1.Nc1cccc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4nccs4)c(F)cc32)n1.O=S(=O)(Cc1ncns1)c1ccc2c(c1)OCC[C@@H]2N1CC[C@@H](C(F)(F)F)C[C@H]1c1ccc(F)c(Cl)c1.O=S(=O)(Nc1nccs1)c1cc2c(cc1F)[C@@H](N1CC[C@@H](C(F)(F)F)C[C@H]1c1ccc(F)cc1)CCO2.

What is the InChIKey of 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide?

The InChIKey is HCFLSJKAUGDKBA-BFORGLBKSA-N. The full InChI is InChI=1S/C25H25F3N4O4S2.C24H22ClF4N3O3S2.C24H22F5N3O3S2.C24H24F4N4O3S2.C23H26F3N5O3S2.C22H24F3N5O3S2/c26-25(27,28)17-6-8-32(21(11-17)15-2-1-3-16(10-15)24(29)33)20-7-9-36-22-12-18(4-5-19(20)22)38(34,35)13-23-30-14-31-37-23;25-18-9-14(1-4-19(18)26)21-10-15(24(27,28)29)5-7-32(21)20-6-8-35-22-11-16(2-3-17(20)22)37(33,34)12-23-30-13-31-36-23;25-16-3-1-14(2-4-16)20-11-15(24(27,28)29)5-8-32(20)19-6-9-35-21-13-22(18(26)12-17(19)21)37(33,34)31-23-30-7-10-36-23;25-16-11-15-18(5-8-35-20(15)12-21(16)37(33,34)13-23-30-6-9-36-23)32-7-4-14(24(26,27)28)10-19(32)17-2-1-3-22(29)31-17;1-14-9-19(30(2)29-14)20-10-15(23(24,25)26)5-7-31(20)18-6-8-34-21-11-16(3-4-17(18)21)36(32,33)12-22-27-13-28-35-22;1-29-7-5-17(28-29)19-10-14(22(23,24)25)4-8-30(19)18-6-9-33-20-11-15(2-3-16(18)20)35(31,32)12-21-26-13-27-34-21/h1-5,10,12,14,17,20-21H,6-9,11,13H2,(H2,29,33);1-4,9,11,13,15,20-21H,5-8,10,12H2;1-4,7,10,12-13,15,19-20H,5-6,8-9,11H2,(H,30,31);1-3,6,9,11-12,14,18-19H,4-5,7-8,10,13H2,(H2,29,31);3-4,9,11,13,15,18,20H,5-8,10,12H2,1-2H3;2-3,5,7,11,13-14,18-19H,4,6,8-10,12H2,1H3/t17-,20+,21+;15-,20+,21+;15-,19+,20+;14-,18+,19+;15-,18+,20+;14-,18+,19+/m111111/s1.

What are the key properties of 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide?

5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide has a molecular weight of 3328.07 g/mol, XLogP of 30.21, 31 rotatable bonds, 3 hydrogen bond donors, and 47 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[[(4S)-4-[(2S,4R)-2-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(2,5-dimethylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;(4S)-6-fluoro-4-[(2S,4R)-2-(4-fluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-N-(1,3-thiazol-2-yl)-3,4-dihydro-2H-chromene-7-sulfonamide;6-[(2S,4R)-1-[(4S)-6-fluoro-7-(1,3-thiazol-2-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]pyridin-2-amine;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;3-[(2S,4R)-1-[(4S)-7-(1,2,4-thiadiazol-5-ylmethylsulfonyl)-3,4-dihydro-2H-chromen-4-yl]-4-(trifluoromethyl)piperidin-2-yl]benzamide is sourced from PubChem (CID 158435959), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).