2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole

C138H137F26N22O18S12+ — CID 158717942

About 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole

2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole (PubChem CID 158717942) has the molecular formula C138H137F26N22O18S12+ and a molecular weight of 3270.50 g/mol. Its IUPAC name is 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole.

Molecular Properties

• Compound Name: 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole
• PubChem CID: 158717942
• Molecular Formula: C138H137F26N22O18S12+
• Molecular Weight: 3270.50 g/mol
• Exact Mass: 3267.67
• IUPAC Name: 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole
• SMILES: C[n+]1cc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4ncns4)ccc32)c[nH]1.Cn1ccc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4ncns4)ccc32)n1.O=S(=O)(Cc1nccs1)c1cc2c(cc1F)[C@@H](N1CC[C@@H](C(F)(F)F)C[C@H]1c1ccc(F)c(F)c1)CCO2.O=S(=O)(Cc1nccs1)c1cc2c(cc1F)[C@@H](N1CC[C@@H](C(F)(F)F)C[C@H]1c1cn[nH]c1)CCO2.O=S(=O)(Cc1nccs1)c1cc2c(cc1F)[C@H](N1CC[C@@H](C(F)(F)F)C[C@H]1c1ccc(F)c(F)c1)CCO2.O=S(=O)(Cc1nccs1)c1cc2c(cc1F)[C@H](N1CC[C@@H](C(F)(F)F)C[C@H]1c1cn[nH]c1)CCO2
• InChI: InChI=1S/2C25H22F6N2O3S2.2C22H22F4N4O3S2.2C22H24F3N5O3S2/c2*26-17-2-1-14(9-18(17)27)21-10-15(25(29,30)31)3-6-33(21)20-4-7-36-22-12-23(19(28)11-16(20)22)38(34,35)13-24-32-5-8-37-24;2*23-16-8-15-17(30-4-1-14(22(24,25)26)7-18(30)13-10-28-29-11-13)2-5-33-19(15)9-20(16)35(31,32)12-21-27-3-6-34-21;1-29-7-5-17(28-29)19-10-14(22(23,24)25)4-8-30(19)18-6-9-33-20-11-15(2-3-16(18)20)35(31,32)12-21-26-13-27-34-21;1-29-11-14(10-27-29)19-8-15(22(23,24)25)4-6-30(19)18-5-7-33-20-9-16(2-3-17(18)20)35(31,32)12-21-26-13-28-34-21/h2*1-2,5,8-9,11-12,15,20-21H,3-4,6-7,10,13H2;2*3,6,8-11,14,17-18H,1-2,4-5,7,12H2,(H,28,29);2-3,5,7,11,13-14,18-19H,4,6,8-10,12H2,1H3;2-3,9-11,13,15,18-19H,4-8,12H2,1H3/p+1/t15-,20+,21+;15-,20-,21+;14-,17+,18+;14-,17-,18+;14-,18+,19+;15-,18+,19+/m111111/s1
• InChIKey: FOWRRKWLLYAXCW-ICFDFZIQSA-O
• XLogP: 29.97
• TPSA: 477.63 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 42
• Rotatable Bonds: 30
• Heavy Atoms: 216
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	3270.50
LogP ≤ 5	29.97
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	42

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'quaternary_nitrogen_1', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole?

The IUPAC name of 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole (CID 158717942) is 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole.

What is the SMILES notation for 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole?

The canonical SMILES for 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole is C[n+]1cc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4ncns4)ccc32)c[nH]1.Cn1ccc([C@@H]2C[C@H](C(F)(F)F)CCN2[C@H]2CCOc3cc(S(=O)(=O)Cc4ncns4)ccc32)n1.O=S(=O)(Cc1nccs1)c1cc2c(cc1F)[C@@H](N1CC[C@@H](C(F)(F)F)C[C@H]1c1ccc(F)c(F)c1)CCO2.O=S(=O)(Cc1nccs1)c1cc2c(cc1F)[C@@H](N1CC[C@@H](C(F)(F)F)C[C@H]1c1cn[nH]c1)CCO2.O=S(=O)(Cc1nccs1)c1cc2c(cc1F)[C@H](N1CC[C@@H](C(F)(F)F)C[C@H]1c1ccc(F)c(F)c1)CCO2.O=S(=O)(Cc1nccs1)c1cc2c(cc1F)[C@H](N1CC[C@@H](C(F)(F)F)C[C@H]1c1cn[nH]c1)CCO2.

What is the InChIKey of 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole?

The InChIKey is FOWRRKWLLYAXCW-ICFDFZIQSA-O. The full InChI is InChI=1S/2C25H22F6N2O3S2.2C22H22F4N4O3S2.2C22H24F3N5O3S2/c2*26-17-2-1-14(9-18(17)27)21-10-15(25(29,30)31)3-6-33(21)20-4-7-36-22-12-23(19(28)11-16(20)22)38(34,35)13-24-32-5-8-37-24;2*23-16-8-15-17(30-4-1-14(22(24,25)26)7-18(30)13-10-28-29-11-13)2-5-33-19(15)9-20(16)35(31,32)12-21-27-3-6-34-21;1-29-7-5-17(28-29)19-10-14(22(23,24)25)4-8-30(19)18-6-9-33-20-11-15(2-3-16(18)20)35(31,32)12-21-26-13-27-34-21;1-29-11-14(10-27-29)19-8-15(22(23,24)25)4-6-30(19)18-5-7-33-20-9-16(2-3-17(18)20)35(31,32)12-21-26-13-28-34-21/h2*1-2,5,8-9,11-12,15,20-21H,3-4,6-7,10,13H2;2*3,6,8-11,14,17-18H,1-2,4-5,7,12H2,(H,28,29);2-3,5,7,11,13-14,18-19H,4,6,8-10,12H2,1H3;2-3,9-11,13,15,18-19H,4-8,12H2,1H3/p+1/t15-,20+,21+;15-,20-,21+;14-,17+,18+;14-,17-,18+;14-,18+,19+;15-,18+,19+/m111111/s1.

What are the key properties of 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole?

2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole has a molecular weight of 3270.50 g/mol, XLogP of 29.97, 30 rotatable bonds, 3 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[[(4S)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-4-[(2S,4R)-2-(3,4-difluorophenyl)-4-(trifluoromethyl)piperidin-1-yl]-6-fluoro-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4S)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;2-[[(4R)-6-fluoro-4-[(2S,4R)-2-(1H-pyrazol-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,3-thiazole;5-[[(4S)-4-[(2S,4R)-2-(2-methyl-1H-pyrazol-2-ium-4-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole;5-[[(4S)-4-[(2S,4R)-2-(1-methylpyrazol-3-yl)-4-(trifluoromethyl)piperidin-1-yl]-3,4-dihydro-2H-chromen-7-yl]sulfonylmethyl]-1,2,4-thiadiazole is sourced from PubChem (CID 158717942), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).