6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide

C145H132F22N26O16S6 — CID 158440024

About 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide

6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide (PubChem CID 158440024) has the molecular formula C145H132F22N26O16S6 and a molecular weight of 3105.17 g/mol. Its IUPAC name is 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide.

Molecular Properties

• Compound Name: 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide
• PubChem CID: 158440024
• Molecular Formula: C145H132F22N26O16S6
• Molecular Weight: 3105.17 g/mol
• Exact Mass: 3102.83
• IUPAC Name: 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide
• SMILES: CC(C)(NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C4CC4)cc3n2-c2ccccn2)nc1)C(F)(F)F.CC(C)(NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(OC(F)F)cc3n2-c2ccccn2)nc1)C(F)(F)F.Cc1c(F)cc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn3)n(C3CCCC3)c2c1F.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn3)n(-c3ccccc3)c2c1.NC(=O)c1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(C3CC3)ccc12.NC(=O)c1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(OC(F)F)ccc12
• InChI: InChI=1S/C26H22F3N5O2S.C25H21F3N4O2S.C24H18F5N5O3S.C24H23F5N4O2S.C24H26F2N4O3S.C22H22F4N4O4S/c1-25(2,26(27,28)29)33-37(35,36)18-9-11-21(32-15-18)24-20(14-30)19-10-8-17(16-6-7-16)13-22(19)34(24)23-5-3-4-12-31-23;1-16-9-11-19-20(14-29)23(32(22(19)13-16)17-7-5-4-6-8-17)21-12-10-18(15-30-21)35(33,34)31-24(2,3)25(26,27)28;1-23(2,24(27,28)29)33-38(35,36)15-7-9-18(32-13-15)21-17(12-30)16-8-6-14(37-22(25)26)11-19(16)34(21)20-5-3-4-10-31-20;1-13-18(25)10-16-17(11-30)21(33(22(16)20(13)26)14-6-4-5-7-14)19-9-8-15(12-31-19)36(34,35)32-23(2,3)24(27,28)29;25-11-16(12-26)29-34(32,33)18-7-9-20(28-13-18)23-22(24(27)31)19-8-6-15(14-4-5-14)10-21(19)30(23)17-2-1-3-17;23-9-12(10-24)29-35(32,33)15-5-7-17(28-11-15)20-19(21(27)31)16-6-4-14(34-22(25)26)8-18(16)30(20)13-2-1-3-13/h3-5,8-13,15-16,33H,6-7H2,1-2H3;4-13,15,31H,1-3H3;3-11,13,22,33H,1-2H3;8-10,12,14,32H,4-7H2,1-3H3;6-10,13-14,16-17,29H,1-5,11-12H2,(H2,27,31);4-8,11-13,22,29H,1-3,9-10H2,(H2,27,31)
• InChIKey: HCRZEMRWKJQYGY-UHFFFAOYSA-N
• XLogP: 29.73
• TPSA: 609.52 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 34
• Rotatable Bonds: 42
• Heavy Atoms: 215
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3105.17
LogP ≤ 5	29.73
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide?

The IUPAC name of 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide (CID 158440024) is 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide.

What is the SMILES notation for 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide?

The canonical SMILES for 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide is CC(C)(NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C4CC4)cc3n2-c2ccccn2)nc1)C(F)(F)F.CC(C)(NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(OC(F)F)cc3n2-c2ccccn2)nc1)C(F)(F)F.Cc1c(F)cc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn3)n(C3CCCC3)c2c1F.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)(C)C(F)(F)F)cn3)n(-c3ccccc3)c2c1.NC(=O)c1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(C3CC3)ccc12.NC(=O)c1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(OC(F)F)ccc12.

What is the InChIKey of 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide?

The InChIKey is HCRZEMRWKJQYGY-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H22F3N5O2S.C25H21F3N4O2S.C24H18F5N5O3S.C24H23F5N4O2S.C24H26F2N4O3S.C22H22F4N4O4S/c1-25(2,26(27,28)29)33-37(35,36)18-9-11-21(32-15-18)24-20(14-30)19-10-8-17(16-6-7-16)13-22(19)34(24)23-5-3-4-12-31-23;1-16-9-11-19-20(14-29)23(32(22(19)13-16)17-7-5-4-6-8-17)21-12-10-18(15-30-21)35(33,34)31-24(2,3)25(26,27)28;1-23(2,24(27,28)29)33-38(35,36)15-7-9-18(32-13-15)21-17(12-30)16-8-6-14(37-22(25)26)11-19(16)34(21)20-5-3-4-10-31-20;1-13-18(25)10-16-17(11-30)21(33(22(16)20(13)26)14-6-4-5-7-14)19-9-8-15(12-31-19)36(34,35)32-23(2,3)24(27,28)29;25-11-16(12-26)29-34(32,33)18-7-9-20(28-13-18)23-22(24(27)31)19-8-6-15(14-4-5-14)10-21(19)30(23)17-2-1-3-17;23-9-12(10-24)29-35(32,33)15-5-7-17(28-11-15)20-19(21(27)31)16-6-4-14(34-22(25)26)8-18(16)30(20)13-2-1-3-13/h3-5,8-13,15-16,33H,6-7H2,1-2H3;4-13,15,31H,1-3H3;3-11,13,22,33H,1-2H3;8-10,12,14,32H,4-7H2,1-3H3;6-10,13-14,16-17,29H,1-5,11-12H2,(H2,27,31);4-8,11-13,22,29H,1-3,9-10H2,(H2,27,31).

What are the key properties of 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide?

6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide has a molecular weight of 3105.17 g/mol, XLogP of 29.73, 42 rotatable bonds, 8 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-cyano-1-cyclopentyl-5,7-difluoro-6-methylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-cyclopropyl-1-pyridin-2-ylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-pyridin-2-ylindol-2-yl]-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-6-methyl-1-phenylindol-2-yl)-N-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine-3-sulfonamide;1-cyclobutyl-6-cyclopropyl-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide;1-cyclobutyl-6-(difluoromethoxy)-2-[5-(1,3-difluoropropan-2-ylsulfamoyl)-2-pyridinyl]indole-3-carboxamide is sourced from PubChem (CID 158440024), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).