6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide

C131H119ClF20N26O14S6 — CID 158443776

About 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide

6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide (PubChem CID 158443776) has the molecular formula C131H119ClF20N26O14S6 and a molecular weight of 2889.38 g/mol. Its IUPAC name is 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide.

Molecular Properties

• Compound Name: 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide
• PubChem CID: 158443776
• Molecular Formula: C131H119ClF20N26O14S6
• Molecular Weight: 2889.38 g/mol
• Exact Mass: 2886.71
• IUPAC Name: 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide
• SMILES: CC(C)n1c(-c2ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn2)c(C#N)c2ccc(OC(F)F)cc21.COc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCCC3)c2c1.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(F)c(Cl)cc3n2C2CCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(CF)cc3n2C2CCC2)nc1)C(F)(F)F.Cc1ccc(-n2c(-c3ncc(S(=O)(=O)NC(C)C)cn3)c(C#N)c3cc(F)ccc32)cc1.N#Cc1c(-c2ncc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(CF)ccc12
• InChI: InChI=1S/C23H23F3N4O3S.C23H20FN5O2S.C22H20F4N4O2S.C21H17ClF4N4O2S.C21H19F5N4O3S.C21H20F3N5O2S/c1-14(23(24,25)26)29-34(31,32)17-8-10-20(28-13-17)22-19(12-27)18-9-7-16(33-2)11-21(18)30(22)15-5-3-4-6-15;1-14(2)28-32(30,31)18-12-26-23(27-13-18)22-20(11-25)19-10-16(24)6-9-21(19)29(22)17-7-4-15(3)5-8-17;1-13(22(24,25)26)29-33(31,32)16-6-8-19(28-12-16)21-18(11-27)17-7-5-14(10-23)9-20(17)30(21)15-3-2-4-15;1-11(21(24,25)26)29-33(31,32)13-5-6-18(28-10-13)20-15(9-27)14-7-17(23)16(22)8-19(14)30(20)12-3-2-4-12;1-11(2)30-18-8-13(33-20(22)23)4-6-15(18)16(9-27)19(30)17-7-5-14(10-28-17)34(31,32)29-12(3)21(24,25)26;22-7-13-4-5-17-18(10-25)20(29(19(17)6-13)15-2-1-3-15)21-26-11-16(12-27-21)32(30,31)28-14(8-23)9-24/h7-11,13-15,29H,3-6H2,1-2H3;4-10,12-14,28H,1-3H3;5-9,12-13,15,29H,2-4,10H2,1H3;5-8,10-12,29H,2-4H2,1H3;4-8,10-12,20,29H,1-3H3;4-6,11-12,14-15,28H,1-3,7-9H2/t14-;;13-;11-;12-;/m0.000./s1
• InChIKey: HDDFLWJTXFZCEI-GVFPOAFNSA-N
• XLogP: 28.08
• TPSA: 570.92 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 34
• Rotatable Bonds: 37
• Heavy Atoms: 198
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2889.38
LogP ≤ 5	28.08
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide?

The IUPAC name of 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide (CID 158443776) is 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide.

What is the SMILES notation for 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide?

The canonical SMILES for 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide is CC(C)n1c(-c2ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn2)c(C#N)c2ccc(OC(F)F)cc21.COc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn3)n(C3CCCC3)c2c1.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(F)c(Cl)cc3n2C2CCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(CF)cc3n2C2CCC2)nc1)C(F)(F)F.Cc1ccc(-n2c(-c3ncc(S(=O)(=O)NC(C)C)cn3)c(C#N)c3cc(F)ccc32)cc1.N#Cc1c(-c2ncc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(CF)ccc12.

What is the InChIKey of 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide?

The InChIKey is HDDFLWJTXFZCEI-GVFPOAFNSA-N. The full InChI is InChI=1S/C23H23F3N4O3S.C23H20FN5O2S.C22H20F4N4O2S.C21H17ClF4N4O2S.C21H19F5N4O3S.C21H20F3N5O2S/c1-14(23(24,25)26)29-34(31,32)17-8-10-20(28-13-17)22-19(12-27)18-9-7-16(33-2)11-21(18)30(22)15-5-3-4-6-15;1-14(2)28-32(30,31)18-12-26-23(27-13-18)22-20(11-25)19-10-16(24)6-9-21(19)29(22)17-7-4-15(3)5-8-17;1-13(22(24,25)26)29-33(31,32)16-6-8-19(28-12-16)21-18(11-27)17-7-5-14(10-23)9-20(17)30(21)15-3-2-4-15;1-11(21(24,25)26)29-33(31,32)13-5-6-18(28-10-13)20-15(9-27)14-7-17(23)16(22)8-19(14)30(20)12-3-2-4-12;1-11(2)30-18-8-13(33-20(22)23)4-6-15(18)16(9-27)19(30)17-7-5-14(10-28-17)34(31,32)29-12(3)21(24,25)26;22-7-13-4-5-17-18(10-25)20(29(19(17)6-13)15-2-1-3-15)21-26-11-16(12-27-21)32(30,31)28-14(8-23)9-24/h7-11,13-15,29H,3-6H2,1-2H3;4-10,12-14,28H,1-3H3;5-9,12-13,15,29H,2-4,10H2,1H3;5-8,10-12,29H,2-4H2,1H3;4-8,10-12,20,29H,1-3H3;4-6,11-12,14-15,28H,1-3,7-9H2/t14-;;13-;11-;12-;/m0.000./s1.

What are the key properties of 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide?

6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide has a molecular weight of 2889.38 g/mol, XLogP of 28.08, 37 rotatable bonds, 6 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(6-chloro-3-cyano-1-cyclobutyl-5-fluoroindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyrimidine-5-sulfonamide;6-[3-cyano-1-cyclobutyl-6-(fluoromethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methoxyindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-6-(difluoromethoxy)-1-propan-2-ylindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;2-[3-cyano-5-fluoro-1-(4-methylphenyl)indol-2-yl]-N-propan-2-ylpyrimidine-5-sulfonamide is sourced from PubChem (CID 158443776), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).