6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide

C180H203F5N38O23S2 — CID 158481617

IUPAC6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide
SMILESCCOc1ncc(-c2cc(C(=O)Nc3ccnc(C(F)(F)F)c3)ccc2C)cc1N1CCOCC1.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)C#N)c3)cnc2C)cc1N1CCOCC1.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)C#N)c3)cnc2C)cc1N1CCOC[C@H]1C.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)F)c3)ccc2C)cc1N1CCOCC1.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)F)c3)cnc2C)cc1N1CCOCC1.[H]N=S(C)(=O)c1cccc(C(=O)Nc2ccc(C)c(-c3cnc(OCC)c(N4CCOCC4)c3)c2)c1.[H]N=S(C)(=O)c1cccc(C(=O)Nc2cnc(C)c(-c3cnc(OCC)c(N4CCOCC4)c3)c2)c1
InChIInChI=1S/C27H31N7O3.C26H30FN5O3.C26H29N7O3.C26H30N4O4S.C25H25F3N4O3.C25H29FN6O3.C25H29N5O4S/c1-6-37-26-23(34-7-8-36-15-17(34)2)9-19(12-30-26)22-11-21(14-29-18(22)3)32-25(35)20-10-24(33-31-13-20)27(4,5)16-28;1-5-35-25-22(32-8-10-34-11-9-32)12-18(15-28-25)21-14-20(7-6-17(21)2)30-24(33)19-13-23(26(3,4)27)31-29-16-19;1-5-36-25-22(33-6-8-35-9-7-33)10-18(13-29-25)21-12-20(15-28-17(21)2)31-24(34)19-11-23(32-30-14-19)26(3,4)16-27;1-4-34-26-24(30-10-12-33-13-11-30)15-20(17-28-26)23-16-21(9-8-18(23)2)29-25(31)19-6-5-7-22(14-19)35(3,27)32;1-3-35-24-21(32-8-10-34-11-9-32)13-18(15-30-24)20-12-17(5-4-16(20)2)23(33)31-19-6-7-29-22(14-19)25(26,27)28;1-5-35-24-21(32-6-8-34-9-7-32)10-17(13-28-24)20-12-19(15-27-16(20)2)30-23(33)18-11-22(25(3,4)26)31-29-14-18;1-4-34-25-23(30-8-10-33-11-9-30)13-19(15-28-25)22-14-20(16-27-17(22)2)29-24(31)18-6-5-7-21(12-18)35(3,26)32/h9-14,17H,6-8,15H2,1-5H3,(H,32,35);6-7,12-16H,5,8-11H2,1-4H3,(H,30,33);10-15H,5-9H2,1-4H3,(H,31,34);5-9,14-17,27H,4,10-13H2,1-3H3,(H,29,31);4-7,12-15H,3,8-11H2,1-2H3,(H,29,31,33);10-15H,5-9H2,1-4H3,(H,30,33);5-7,12-16,26H,4,8-11H2,1-3H3,(H,29,31)/t17-;;;;;;/m1....../s1
InChIKeyHHOVFBYQFWIHIJ-MFGRGHSBSA-N
MW3425.97 g/mol
LogP29.44
Rot. Bonds48

About 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide

6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide (PubChem CID 158481617) has the molecular formula C180H203F5N38O23S2 and a molecular weight of 3425.97 g/mol. Its IUPAC name is 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide.

Molecular Properties

Compound Name6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide
PubChem CID158481617
Molecular FormulaC180H203F5N38O23S2
Molecular Weight3425.97 g/mol
Exact Mass3423.52
IUPAC Name6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide
SMILESCCOc1ncc(-c2cc(C(=O)Nc3ccnc(C(F)(F)F)c3)ccc2C)cc1N1CCOCC1.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)C#N)c3)cnc2C)cc1N1CCOCC1.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)C#N)c3)cnc2C)cc1N1CCOC[C@H]1C.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)F)c3)ccc2C)cc1N1CCOCC1.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)F)c3)cnc2C)cc1N1CCOCC1.[H]N=S(C)(=O)c1cccc(C(=O)Nc2ccc(C)c(-c3cnc(OCC)c(N4CCOCC4)c3)c2)c1.[H]N=S(C)(=O)c1cccc(C(=O)Nc2cnc(C)c(-c3cnc(OCC)c(N4CCOCC4)c3)c2)c1
InChIInChI=1S/C27H31N7O3.C26H30FN5O3.C26H29N7O3.C26H30N4O4S.C25H25F3N4O3.C25H29FN6O3.C25H29N5O4S/c1-6-37-26-23(34-7-8-36-15-17(34)2)9-19(12-30-26)22-11-21(14-29-18(22)3)32-25(35)20-10-24(33-31-13-20)27(4,5)16-28;1-5-35-25-22(32-8-10-34-11-9-32)12-18(15-28-25)21-14-20(7-6-17(21)2)30-24(33)19-13-23(26(3,4)27)31-29-16-19;1-5-36-25-22(33-6-8-35-9-7-33)10-18(13-29-25)21-12-20(15-28-17(21)2)31-24(34)19-11-23(32-30-14-19)26(3,4)16-27;1-4-34-26-24(30-10-12-33-13-11-30)15-20(17-28-26)23-16-21(9-8-18(23)2)29-25(31)19-6-5-7-22(14-19)35(3,27)32;1-3-35-24-21(32-8-10-34-11-9-32)13-18(15-30-24)20-12-17(5-4-16(20)2)23(33)31-19-6-7-29-22(14-19)25(26,27)28;1-5-35-24-21(32-6-8-34-9-7-32)10-17(13-28-24)20-12-19(15-27-16(20)2)30-23(33)18-11-22(25(3,4)26)31-29-14-18;1-4-34-25-23(30-8-10-33-11-9-30)13-19(15-28-25)22-14-20(16-27-17(22)2)29-24(31)18-6-5-7-21(12-18)35(3,26)32/h9-14,17H,6-8,15H2,1-5H3,(H,32,35);6-7,12-16H,5,8-11H2,1-4H3,(H,30,33);10-15H,5-9H2,1-4H3,(H,31,34);5-9,14-17,27H,4,10-13H2,1-3H3,(H,29,31);4-7,12-15H,3,8-11H2,1-2H3,(H,29,31,33);10-15H,5-9H2,1-4H3,(H,30,33);5-7,12-16,26H,4,8-11H2,1-3H3,(H,29,31)/t17-;;;;;;/m1....../s1
InChIKeyHHOVFBYQFWIHIJ-MFGRGHSBSA-N
XLogP29.44
TPSA742.82 Ų
H-Bond Donors9
H-Bond Acceptors54
Rotatable Bonds48
Heavy Atoms248
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5003425.97
LogP ≤ 529.44
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1054

Analyze 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide with MolForge

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Launch Full Analysis

Related Compounds

N-[3-(6-ethoxy-5-morpholin-4-ylpyridin-3-yl)-4-methylphenyl]-5-[2-[[[3-[[3-(6-ethoxy-5-morpholin-4-ylpyridin-3-yl)-4-methylphenyl]carbamoyl]phenyl]-methyl-oxo-lambda6-sulfanylidene]amino]ethoxy]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 130425579
2-(2-cyanopropan-2-yl)-N-[3-[5-[(3R)-2-[2-[6-[5-[[2-(2-cyanopropan-2-yl)pyridine-4-carbonyl]amino]-2-methyl-3-pyridinyl]-4-[(3R)-3-methyl-2-[2-[4-[(3R)-3-methylmorpholin-4-yl]-6-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]-3-pyridinyl]pyridazin-3-yl]oxyethyl]morpholin-4-yl]pyridazin-3-yl]oxyethyl]-3-methylmorpholin-4-yl]-6-ethoxypyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 130425581
6-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[2-[2-[6-[2-methyl-5-[[2-(trifluoromethyl)pyridine-4-carbonyl]amino]phenyl]-4-morpholin-4-ylpyridazin-3-yl]oxyethyl]morpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridazine-4-carboxamide
CID 130425658
2-(2-cyanopropan-2-yl)-N-[3-[6-[1-[4-[6-[5-[[2-(1,1-difluoroethyl)pyridine-4-carbonyl]amino]-2-methylphenyl]-3-(2-methoxyethoxy)pyridazin-4-yl]morpholin-2-yl]propan-2-yloxy]-5-[2-[2-[6-[5-[[2-(2-fluoropropan-2-yl)pyridine-4-carbonyl]amino]-2-methylphenyl]-4-morpholin-4-ylpyridazin-3-yl]oxypropyl]morpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 130425721
2-(1,1-difluoroethyl)-N-[3-[6-[2-[4-[3-ethoxy-6-[2-methyl-5-[(3-methylsulfonylbenzoyl)amino]phenyl]pyridazin-4-yl]morpholin-2-yl]ethoxy]-5-morpholin-4-ylpyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide
CID 130425814
5-ethoxy-N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;bis(N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide);1-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-(2-methylsulfonyl-4-pyridinyl)ethanone;2-[4-[2-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-2-oxoethyl]-2-pyridinyl]-2-methylpropanenitrile;[[4-[2-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-2-oxoethyl]-2-pyridinyl]-dimethyl-lambda4-sulfanyl]formonitrile
CID 157095397
2-cyclopropyl-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;2-(1,1-difluoropropyl)-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-(2-fluoropropan-2-yl)-N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[5-(6-methoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[4-methyl-3-(6-methylsulfonyl-5-morpholin-4-ylpyridazin-3-yl)phenyl]-3-(trifluoromethyl)benzamide
CID 157258499
2-(2-cyanopropan-2-yl)-N-[3-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-4-methylphenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]benzamide;N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-3-methylsulfonylbenzamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-6-methyl-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[5-[6-ethoxy-5-[2-(3H-pyrrol-2-yl)morpholin-4-yl]pyridazin-3-yl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157268806
2-(1-cyanocyclopropyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridazine-4-carboxamide;2-cyclopropyl-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]pyridine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-2-fluoro-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-(2-fluoropropan-2-yl)pyridine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-ylpyridazin-3-yl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 157274240
2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridazin-3-yl]phenyl]pyridine-4-carboxamide;N-ethyl-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-methyl-N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[4-methyl-3-[5-morpholin-4-yl-6-(oxan-4-yloxy)pyridazin-3-yl]phenyl]-6-(trifluoromethyl)pyridazine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-2-propan-2-ylpyridine-4-carboxamide;N-[6-methyl-5-[5-morpholin-4-yl-6-(oxan-4-yloxy)-3-pyridinyl]-3-pyridinyl]-N-propyl-3-(trifluoromethyl)benzamide
CID 157325132
N-[5-[6-(azetidin-3-yloxy)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;2-(2-cyanopropan-2-yl)-N-[5-(1-ethyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;N-[5-[6-(2-cyanopropan-2-yl)-5-morpholin-4-yl-3-pyridinyl]-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide;N-[3-(1-ethyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide;4-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-3-(trifluoromethyl)benzamide;N-[5-(6-methoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[6-methyl-5-[6-(methylsulfonylmethyl)-5-morpholin-4-yl-3-pyridinyl]-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157502605
4-(2-cyanopropan-2-yl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxopyridazin-3-yl)phenyl]pyridine-2-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-ylpyridazin-3-yl]-6-methyl-3-pyridinyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-ylpyridazin-3-yl]-6-methyl-3-pyridinyl]-2-(1,1-difluoropropyl)pyridine-4-carboxamide;N-[5-[6-(2,2-difluoroethoxy)-5-morpholin-4-ylpyridazin-3-yl]-6-methyl-3-pyridinyl]-4-(trifluoromethyl)pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxypyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;2-(difluoromethyl)-N-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxypyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[6-methyl-5-(5-morpholin-4-yl-6-propan-2-yloxypyridazin-3-yl)-3-pyridinyl]pyridine-4-carboxamide
CID 157584913

Frequently Asked Questions

What is the IUPAC name of 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide?
The IUPAC name of 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide (CID 158481617) is 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide.
What is the SMILES notation for 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide?
The canonical SMILES for 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide is CCOc1ncc(-c2cc(C(=O)Nc3ccnc(C(F)(F)F)c3)ccc2C)cc1N1CCOCC1.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)C#N)c3)cnc2C)cc1N1CCOCC1.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)C#N)c3)cnc2C)cc1N1CCOC[C@H]1C.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)F)c3)ccc2C)cc1N1CCOCC1.CCOc1ncc(-c2cc(NC(=O)c3cnnc(C(C)(C)F)c3)cnc2C)cc1N1CCOCC1.[H]N=S(C)(=O)c1cccc(C(=O)Nc2ccc(C)c(-c3cnc(OCC)c(N4CCOCC4)c3)c2)c1.[H]N=S(C)(=O)c1cccc(C(=O)Nc2cnc(C)c(-c3cnc(OCC)c(N4CCOCC4)c3)c2)c1.
What is the InChIKey of 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide?
The InChIKey is HHOVFBYQFWIHIJ-MFGRGHSBSA-N. The full InChI is InChI=1S/C27H31N7O3.C26H30FN5O3.C26H29N7O3.C26H30N4O4S.C25H25F3N4O3.C25H29FN6O3.C25H29N5O4S/c1-6-37-26-23(34-7-8-36-15-17(34)2)9-19(12-30-26)22-11-21(14-29-18(22)3)32-25(35)20-10-24(33-31-13-20)27(4,5)16-28;1-5-35-25-22(32-8-10-34-11-9-32)12-18(15-28-25)21-14-20(7-6-17(21)2)30-24(33)19-13-23(26(3,4)27)31-29-16-19;1-5-36-25-22(33-6-8-35-9-7-33)10-18(13-29-25)21-12-20(15-28-17(21)2)31-24(34)19-11-23(32-30-14-19)26(3,4)16-27;1-4-34-26-24(30-10-12-33-13-11-30)15-20(17-28-26)23-16-21(9-8-18(23)2)29-25(31)19-6-5-7-22(14-19)35(3,27)32;1-3-35-24-21(32-8-10-34-11-9-32)13-18(15-30-24)20-12-17(5-4-16(20)2)23(33)31-19-6-7-29-22(14-19)25(26,27)28;1-5-35-24-21(32-6-8-34-9-7-32)10-17(13-28-24)20-12-19(15-27-16(20)2)30-23(33)18-11-22(25(3,4)26)31-29-14-18;1-4-34-25-23(30-8-10-33-11-9-30)13-19(15-28-25)22-14-20(16-27-17(22)2)29-24(31)18-6-5-7-21(12-18)35(3,26)32/h9-14,17H,6-8,15H2,1-5H3,(H,32,35);6-7,12-16H,5,8-11H2,1-4H3,(H,30,33);10-15H,5-9H2,1-4H3,(H,31,34);5-9,14-17,27H,4,10-13H2,1-3H3,(H,29,31);4-7,12-15H,3,8-11H2,1-2H3,(H,29,31,33);10-15H,5-9H2,1-4H3,(H,30,33);5-7,12-16,26H,4,8-11H2,1-3H3,(H,29,31)/t17-;;;;;;/m1....../s1.
What are the key properties of 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide?
6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide has a molecular weight of 3425.97 g/mol, XLogP of 29.44, 48 rotatable bonds, 9 hydrogen bond donors, and 54 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(2-cyanopropan-2-yl)-N-[5-[6-ethoxy-5-[(3R)-3-methylmorpholin-4-yl]-3-pyridinyl]-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;6-(2-cyanopropan-2-yl)-N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methylphenyl]-3-(methylsulfonimidoyl)benzamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-6-(2-fluoropropan-2-yl)pyridazine-4-carboxamide;N-[5-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-6-methyl-3-pyridinyl]-3-(methylsulfonimidoyl)benzamide;3-(6-ethoxy-5-morpholin-4-yl-3-pyridinyl)-4-methyl-N-[2-(trifluoromethyl)-4-pyridinyl]benzamide is sourced from PubChem (CID 158481617), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).