N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide

C135H181Cl2F6N33O12 — CID 158645934

About N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide (PubChem CID 158645934) has the molecular formula C135H181Cl2F6N33O12 and a molecular weight of 2643.05 g/mol. Its IUPAC name is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide.

Molecular Properties

• Compound Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide
• PubChem CID: 158645934
• Molecular Formula: C135H181Cl2F6N33O12
• Molecular Weight: 2643.05 g/mol
• Exact Mass: 2640.38
• IUPAC Name: N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide
• SMILES: C=Cc1ccc2nc(NC(=O)CC(C)(C)C)n(CC(F)(F)F)c2n1.CC(C)(C)OCCC(=O)Nc1nc2ccc(-c3cccnc3)nc2n1C1CCC1.CCCn1c(NC(=O)CC(C)(C)OC)nc2ccc(Cl)nc21.CCc1ccc2nc(NC(=O)CC(C)(C)C)n(CC(F)(F)F)c2n1.COC(C)(C)CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C(C)C)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)O)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCC(C)(C)C)n(C3CCC3)c2n1
• InChI: InChI=1S/C22H27N5O2.C18H26N4O.C16H21ClN4O2.C16H21F3N4O.C16H19F3N4O.C16H22N4O2.C16H24N4O.C15H21ClN4O2/c1-22(2,3)29-13-11-19(28)26-21-25-18-10-9-17(15-6-5-12-23-14-15)24-20(18)27(21)16-7-4-8-16;1-12-8-9-14-16(19-12)22(13-6-5-7-13)17(20-14)21-15(23)10-11-18(2,3)4;1-16(2,23-3)9-13(22)20-15-18-11-7-8-12(17)19-14(11)21(15)10-5-4-6-10;2*1-5-10-6-7-11-13(20-10)23(9-16(17,18)19)14(21-11)22-12(24)8-15(2,3)4;1-10-7-8-12-14(17-10)20(11-5-4-6-11)15(18-12)19-13(21)9-16(2,3)22;1-10(2)20-14-12(8-7-11(3)17-14)18-15(20)19-13(21)9-16(4,5)6;1-5-8-20-13-10(6-7-11(16)18-13)17-14(20)19-12(21)9-15(2,3)22-4/h5-6,9-10,12,14,16H,4,7-8,11,13H2,1-3H3,(H,25,26,28);8-9,13H,5-7,10-11H2,1-4H3,(H,20,21,23);7-8,10H,4-6,9H2,1-3H3,(H,18,20,22);6-7H,5,8-9H2,1-4H3,(H,21,22,24);5-7H,1,8-9H2,2-4H3,(H,21,22,24);7-8,11,22H,4-6,9H2,1-3H3,(H,18,19,21);7-8,10H,9H2,1-6H3,(H,18,19,21);6-7H,5,8-9H2,1-4H3,(H,17,19,21)
• InChIKey: IAYRRHMCWQULCJ-UHFFFAOYSA-N
• XLogP: 29.60
• TPSA: 539.29 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 37
• Rotatable Bonds: 36
• Heavy Atoms: 188
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2643.05
LogP ≤ 5	29.60
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	37

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

The IUPAC name of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide (CID 158645934) is N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide.

What is the SMILES notation for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

The canonical SMILES for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide is C=Cc1ccc2nc(NC(=O)CC(C)(C)C)n(CC(F)(F)F)c2n1.CC(C)(C)OCCC(=O)Nc1nc2ccc(-c3cccnc3)nc2n1C1CCC1.CCCn1c(NC(=O)CC(C)(C)OC)nc2ccc(Cl)nc21.CCc1ccc2nc(NC(=O)CC(C)(C)C)n(CC(F)(F)F)c2n1.COC(C)(C)CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1.Cc1ccc2nc(NC(=O)CC(C)(C)C)n(C(C)C)c2n1.Cc1ccc2nc(NC(=O)CC(C)(C)O)n(C3CCC3)c2n1.Cc1ccc2nc(NC(=O)CCC(C)(C)C)n(C3CCC3)c2n1.

What is the InChIKey of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

The InChIKey is IAYRRHMCWQULCJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H27N5O2.C18H26N4O.C16H21ClN4O2.C16H21F3N4O.C16H19F3N4O.C16H22N4O2.C16H24N4O.C15H21ClN4O2/c1-22(2,3)29-13-11-19(28)26-21-25-18-10-9-17(15-6-5-12-23-14-15)24-20(18)27(21)16-7-4-8-16;1-12-8-9-14-16(19-12)22(13-6-5-7-13)17(20-14)21-15(23)10-11-18(2,3)4;1-16(2,23-3)9-13(22)20-15-18-11-7-8-12(17)19-14(11)21(15)10-5-4-6-10;2*1-5-10-6-7-11-13(20-10)23(9-16(17,18)19)14(21-11)22-12(24)8-15(2,3)4;1-10-7-8-12-14(17-10)20(11-5-4-6-11)15(18-12)19-13(21)9-16(2,3)22;1-10(2)20-14-12(8-7-11(3)17-14)18-15(20)19-13(21)9-16(4,5)6;1-5-8-20-13-10(6-7-11(16)18-13)17-14(20)19-12(21)9-15(2,3)22-4/h5-6,9-10,12,14,16H,4,7-8,11,13H2,1-3H3,(H,25,26,28);8-9,13H,5-7,10-11H2,1-4H3,(H,20,21,23);7-8,10H,4-6,9H2,1-3H3,(H,18,20,22);6-7H,5,8-9H2,1-4H3,(H,21,22,24);5-7H,1,8-9H2,2-4H3,(H,21,22,24);7-8,11,22H,4-6,9H2,1-3H3,(H,18,19,21);7-8,10H,9H2,1-6H3,(H,18,19,21);6-7H,5,8-9H2,1-4H3,(H,17,19,21).

What are the key properties of N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide has a molecular weight of 2643.05 g/mol, XLogP of 29.60, 36 rotatable bonds, 9 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(5-chloro-3-propylimidazo[4,5-b]pyridin-2-yl)-3-methoxy-3-methylbutanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-4,4-dimethylpentanamide;N-(3-cyclobutyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-methylbutanamide;N-(3-cyclobutyl-5-pyridin-3-ylimidazo[4,5-b]pyridin-2-yl)-3-[(2-methylpropan-2-yl)oxy]propanamide;3,3-dimethyl-N-(5-methyl-3-propan-2-ylimidazo[4,5-b]pyridin-2-yl)butanamide;N-[5-ethenyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide;N-[5-ethyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide is sourced from PubChem (CID 158645934), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).