2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine

C97H64F21N25O3 — CID 158703146

About 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine

2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine (PubChem CID 158703146) has the molecular formula C97H64F21N25O3 and a molecular weight of 2026.71 g/mol. Its IUPAC name is 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine.

Molecular Properties

• Compound Name: 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine
• PubChem CID: 158703146
• Molecular Formula: C97H64F21N25O3
• Molecular Weight: 2026.71 g/mol
• Exact Mass: 2025.53
• IUPAC Name: 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine
• SMILES: Cc1nc2ccc(F)cn2c1-c1cc(C#N)cc(Nc2ccc(OC(F)F)c(F)c2)n1.Cc1nc2ccc(F)cn2c1-c1cncc(Nc2ccc(C(F)(F)F)c(F)c2)n1.Cc1nc2ccc(F)cn2c1-c1cncc(Nc2ccc(OC(F)F)c(F)c2)n1.Cc1nc2ccccc2n1-c1cncc(Nc2ccc(OC(F)(F)C(F)F)cc2)n1.Fc1ccc2ncc(-c3cncc(Nc4ccc(C(F)(F)F)cc4)n3)n2c1
• InChI: InChI=1S/C21H13F4N5O.C20H15F4N5O.C19H12F5N5.C19H13F4N5O.C18H11F4N5/c1-11-20(30-10-13(22)2-5-19(30)27-11)16-6-12(9-26)7-18(29-16)28-14-3-4-17(15(23)8-14)31-21(24)25;1-12-26-15-4-2-3-5-16(15)29(12)18-11-25-10-17(28-18)27-13-6-8-14(9-7-13)30-20(23,24)19(21)22;1-10-18(29-9-11(20)2-5-17(29)26-10)15-7-25-8-16(28-15)27-12-3-4-13(14(21)6-12)19(22,23)24;1-10-18(28-9-11(20)2-5-17(28)25-10)14-7-24-8-16(27-14)26-12-3-4-15(13(21)6-12)29-19(22)23;19-12-3-6-17-24-8-15(27(17)10-12)14-7-23-9-16(26-14)25-13-4-1-11(2-5-13)18(20,21)22/h2-8,10,21H,1H3,(H,28,29);2-11,19H,1H3,(H,27,28);2-9H,1H3,(H,27,28);2-9,19H,1H3,(H,26,27);1-10H,(H,25,26)
• InChIKey: IHUJDWYRVRACOC-UHFFFAOYSA-N
• XLogP: 24.86
• TPSA: 314.66 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 28
• Rotatable Bonds: 22
• Heavy Atoms: 146
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2026.71
LogP ≤ 5	24.86
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	28

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Perfluorinated_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine?

The IUPAC name of 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine (CID 158703146) is 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine.

What is the SMILES notation for 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine?

The canonical SMILES for 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine is Cc1nc2ccc(F)cn2c1-c1cc(C#N)cc(Nc2ccc(OC(F)F)c(F)c2)n1.Cc1nc2ccc(F)cn2c1-c1cncc(Nc2ccc(C(F)(F)F)c(F)c2)n1.Cc1nc2ccc(F)cn2c1-c1cncc(Nc2ccc(OC(F)F)c(F)c2)n1.Cc1nc2ccccc2n1-c1cncc(Nc2ccc(OC(F)(F)C(F)F)cc2)n1.Fc1ccc2ncc(-c3cncc(Nc4ccc(C(F)(F)F)cc4)n3)n2c1.

What is the InChIKey of 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine?

The InChIKey is IHUJDWYRVRACOC-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H13F4N5O.C20H15F4N5O.C19H12F5N5.C19H13F4N5O.C18H11F4N5/c1-11-20(30-10-13(22)2-5-19(30)27-11)16-6-12(9-26)7-18(29-16)28-14-3-4-17(15(23)8-14)31-21(24)25;1-12-26-15-4-2-3-5-16(15)29(12)18-11-25-10-17(28-18)27-13-6-8-14(9-7-13)30-20(23,24)19(21)22;1-10-18(29-9-11(20)2-5-17(29)26-10)15-7-25-8-16(28-15)27-12-3-4-13(14(21)6-12)19(22,23)24;1-10-18(28-9-11(20)2-5-17(28)25-10)14-7-24-8-16(27-14)26-12-3-4-15(13(21)6-12)29-19(22)23;19-12-3-6-17-24-8-15(27(17)10-12)14-7-23-9-16(26-14)25-13-4-1-11(2-5-13)18(20,21)22/h2-8,10,21H,1H3,(H,28,29);2-11,19H,1H3,(H,27,28);2-9H,1H3,(H,27,28);2-9,19H,1H3,(H,26,27);1-10H,(H,25,26).

What are the key properties of 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine?

2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine has a molecular weight of 2026.71 g/mol, XLogP of 24.86, 22 rotatable bonds, 5 hydrogen bond donors, and 28 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[4-(difluoromethoxy)-3-fluoroanilino]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyridine-4-carbonitrile;N-[4-(difluoromethoxy)-3-fluorophenyl]-6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)pyrazin-2-amine;6-(6-fluoroimidazo[1,2-a]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(6-fluoro-2-methylimidazo[1,2-a]pyridin-3-yl)-N-[3-fluoro-4-(trifluoromethyl)phenyl]pyrazin-2-amine;6-(2-methylbenzimidazol-1-yl)-N-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]pyrazin-2-amine is sourced from PubChem (CID 158703146), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).