5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine

C89H61F5N24 — CID 158728773

About 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine

5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine (PubChem CID 158728773) has the molecular formula C89H61F5N24 and a molecular weight of 1561.62 g/mol. Its IUPAC name is 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine.

Molecular Properties

• Compound Name: 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine
• PubChem CID: 158728773
• Molecular Formula: C89H61F5N24
• Molecular Weight: 1561.62 g/mol
• Exact Mass: 1560.54
• IUPAC Name: 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine
• SMILES: CN1CCC(n2cc(-c3cncc(-c4cc(-c5ccccc5F)nc5nccnc45)c3)cn2)CC1.Fc1ccccc1-c1cc(-n2ccc3cnccc32)c2nccnc2n1.Nc1ncc(-c2cc(-c3ccccc3F)nc3nccnc23)c2ccncc12.Nc1nccc2c(-c3cc(-c4cc(F)ccc4F)nc4nccnc34)nccc12
• InChI: InChI=1S/C27H24FN7.C21H12F2N6.C21H13FN6.C20H12FN5/c1-34-10-6-21(7-11-34)35-17-20(16-32-35)18-12-19(15-29-14-18)23-13-25(22-4-2-3-5-24(22)28)33-27-26(23)30-8-9-31-27;22-11-1-2-16(23)14(9-11)17-10-15(19-21(29-17)28-8-7-26-19)18-12-3-6-27-20(24)13(12)4-5-25-18;22-17-4-2-1-3-13(17)18-9-14(19-21(28-18)26-8-7-25-19)15-11-27-20(23)16-10-24-6-5-12(15)16;21-15-4-2-1-3-14(15)16-11-18(19-20(25-16)24-9-8-23-19)26-10-6-13-12-22-7-5-17(13)26/h2-5,8-9,12-17,21H,6-7,10-11H2,1H3;1-10H,(H2,24,27);1-11H,(H2,23,27);1-12H
• InChIKey: IKVKBHOJSNSYKS-UHFFFAOYSA-N
• XLogP: 17.38
• TPSA: 310.05 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 24
• Rotatable Bonds: 10
• Heavy Atoms: 118
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1561.62
LogP ≤ 5	17.38
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	24

Frequently Asked Questions

What is the IUPAC name of 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine?

The IUPAC name of 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine (CID 158728773) is 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine.

What is the SMILES notation for 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine?

The canonical SMILES for 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine is CN1CCC(n2cc(-c3cncc(-c4cc(-c5ccccc5F)nc5nccnc45)c3)cn2)CC1.Fc1ccccc1-c1cc(-n2ccc3cnccc32)c2nccnc2n1.Nc1ncc(-c2cc(-c3ccccc3F)nc3nccnc23)c2ccncc12.Nc1nccc2c(-c3cc(-c4cc(F)ccc4F)nc4nccnc34)nccc12.

What is the InChIKey of 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine?

The InChIKey is IKVKBHOJSNSYKS-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H24FN7.C21H12F2N6.C21H13FN6.C20H12FN5/c1-34-10-6-21(7-11-34)35-17-20(16-32-35)18-12-19(15-29-14-18)23-13-25(22-4-2-3-5-24(22)28)33-27-26(23)30-8-9-31-27;22-11-1-2-16(23)14(9-11)17-10-15(19-21(29-17)28-8-7-26-19)18-12-3-6-27-20(24)13(12)4-5-25-18;22-17-4-2-1-3-13(17)18-9-14(19-21(28-18)26-8-7-25-19)15-11-27-20(23)16-10-24-6-5-12(15)16;21-15-4-2-1-3-14(15)16-11-18(19-20(25-16)24-9-8-23-19)26-10-6-13-12-22-7-5-17(13)26/h2-5,8-9,12-17,21H,6-7,10-11H2,1H3;1-10H,(H2,24,27);1-11H,(H2,23,27);1-12H.

What are the key properties of 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine?

5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine has a molecular weight of 1561.62 g/mol, XLogP of 17.38, 10 rotatable bonds, 2 hydrogen bond donors, and 24 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[6-(2,5-difluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,6-naphthyridin-1-amine;6-(2-fluorophenyl)-8-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]pyrido[2,3-b]pyrazine;4-[6-(2-fluorophenyl)pyrido[2,3-b]pyrazin-8-yl]-2,7-naphthyridin-1-amine;6-(2-fluorophenyl)-8-pyrrolo[3,2-c]pyridin-1-ylpyrido[2,3-b]pyrazine is sourced from PubChem (CID 158728773), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).