2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile

C128H93F21N28O6S — CID 158784276

About 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile

2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile (PubChem CID 158784276) has the molecular formula C128H93F21N28O6S and a molecular weight of 2550.37 g/mol. Its IUPAC name is 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile.

Molecular Properties

• Compound Name: 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile
• PubChem CID: 158784276
• Molecular Formula: C128H93F21N28O6S
• Molecular Weight: 2550.37 g/mol
• Exact Mass: 2548.72
• IUPAC Name: 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile
• SMILES: CN1C(=O)C(c2cc(CF)ccn2)(c2cc(-c3ccc(F)cc3)c(F)cc2F)N=C1N.CN1C(=O)C(c2cc(CF)ccn2)(c2cc(-c3cccc(C#N)c3)c(F)cc2F)N=C1N.CN1C(=O)C(c2cc(CF)ccn2)(c2cc(-c3ccccc3)c(F)cc2F)N=C1N.CN1C(=O)C(c2cc(CF)ccn2)(c2cc(-c3ccccc3F)c(F)cc2F)N=C1N.CN1C(=O)C(c2cccc(CF)n2)(c2cc(-c3cnc(F)nc3)c(F)cc2F)N=C1N.CN1C(=O)C(c2cccc(CF)n2)(c2cc(-c3cscn3)c(F)cc2F)N=C1N
• InChI: InChI=1S/C23H16F3N5O.2C22H16F4N4O.C22H17F3N4O.C20H14F4N6O.C19H14F3N5OS/c1-31-21(32)23(30-22(31)28,20-8-13(11-24)5-6-29-20)17-9-16(18(25)10-19(17)26)15-4-2-3-14(7-15)12-27;1-30-20(31)22(29-21(30)27,19-8-12(11-23)6-7-28-19)16-9-15(17(25)10-18(16)26)13-2-4-14(24)5-3-13;1-30-20(31)22(29-21(30)27,19-8-12(11-23)6-7-28-19)15-9-14(17(25)10-18(15)26)13-4-2-3-5-16(13)24;1-29-20(30)22(28-21(29)26,19-9-13(12-23)7-8-27-19)16-10-15(17(24)11-18(16)25)14-5-3-2-4-6-14;1-30-17(31)20(29-19(30)25,16-4-2-3-11(7-21)28-16)13-5-12(14(22)6-15(13)23)10-8-26-18(24)27-9-10;1-27-17(28)19(26-18(27)23,16-4-2-3-10(7-20)25-16)12-5-11(13(21)6-14(12)22)15-8-29-9-24-15/h2-10H,11H2,1H3,(H2,28,30);2*2-10H,11H2,1H3,(H2,27,29);2-11H,12H2,1H3,(H2,26,28);2-6,8-9H,7H2,1H3,(H2,25,29);2-6,8-9H,7H2,1H3,(H2,23,26)
• InChIKey: IRLZPFURFNPWBX-UHFFFAOYSA-N
• XLogP: 19.70
• TPSA: 491.94 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 29
• Rotatable Bonds: 24
• Heavy Atoms: 184
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2550.37
LogP ≤ 5	19.70
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	29

Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile?

The IUPAC name of 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile (CID 158784276) is 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile.

What is the SMILES notation for 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile?

The canonical SMILES for 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile is CN1C(=O)C(c2cc(CF)ccn2)(c2cc(-c3ccc(F)cc3)c(F)cc2F)N=C1N.CN1C(=O)C(c2cc(CF)ccn2)(c2cc(-c3cccc(C#N)c3)c(F)cc2F)N=C1N.CN1C(=O)C(c2cc(CF)ccn2)(c2cc(-c3ccccc3)c(F)cc2F)N=C1N.CN1C(=O)C(c2cc(CF)ccn2)(c2cc(-c3ccccc3F)c(F)cc2F)N=C1N.CN1C(=O)C(c2cccc(CF)n2)(c2cc(-c3cnc(F)nc3)c(F)cc2F)N=C1N.CN1C(=O)C(c2cccc(CF)n2)(c2cc(-c3cscn3)c(F)cc2F)N=C1N.

What is the InChIKey of 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile?

The InChIKey is IRLZPFURFNPWBX-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H16F3N5O.2C22H16F4N4O.C22H17F3N4O.C20H14F4N6O.C19H14F3N5OS/c1-31-21(32)23(30-22(31)28,20-8-13(11-24)5-6-29-20)17-9-16(18(25)10-19(17)26)15-4-2-3-14(7-15)12-27;1-30-20(31)22(29-21(30)27,19-8-12(11-23)6-7-28-19)16-9-15(17(25)10-18(16)26)13-2-4-14(24)5-3-13;1-30-20(31)22(29-21(30)27,19-8-12(11-23)6-7-28-19)15-9-14(17(25)10-18(15)26)13-4-2-3-5-16(13)24;1-29-20(30)22(28-21(29)26,19-9-13(12-23)7-8-27-19)16-10-15(17(24)11-18(16)25)14-5-3-2-4-6-14;1-30-17(31)20(29-19(30)25,16-4-2-3-11(7-21)28-16)13-5-12(14(22)6-15(13)23)10-8-26-18(24)27-9-10;1-27-17(28)19(26-18(27)23,16-4-2-3-10(7-20)25-16)12-5-11(13(21)6-14(12)22)15-8-29-9-24-15/h2-10H,11H2,1H3,(H2,28,30);2*2-10H,11H2,1H3,(H2,27,29);2-11H,12H2,1H3,(H2,26,28);2-6,8-9H,7H2,1H3,(H2,25,29);2-6,8-9H,7H2,1H3,(H2,23,26).

What are the key properties of 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile?

2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile has a molecular weight of 2550.37 g/mol, XLogP of 19.70, 24 rotatable bonds, 6 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 2-amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile is sourced from PubChem (CID 158784276), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).