2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile

C128H87F27N28O6S — CID 159165585

IUPAC2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile
SMILESCN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3ccc(F)cc3)ccc2F)N=C1N.CN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3cccc(C#N)c3)ccc2F)N=C1N.CN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3ccccc3)ccc2F)N=C1N.CN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3ccccc3F)ccc2F)N=C1N.CN1C(=O)C(c2cccc(C(F)(F)F)n2)(c2cc(-c3cnc(F)nc3)ccc2F)N=C1N.CN1C(=O)C(c2cccc(C(F)(F)F)n2)(c2cc(-c3cscn3)ccc2F)N=C1N
InChIInChI=1S/C23H15F4N5O.2C22H15F5N4O.C22H16F4N4O.C20H13F5N6O.C19H13F4N5OS/c1-32-20(33)22(31-21(32)29,19-11-16(7-8-30-19)23(25,26)27)17-10-15(5-6-18(17)24)14-4-2-3-13(9-14)12-28;1-31-19(32)21(30-20(31)28,18-11-14(8-9-29-18)22(25,26)27)16-10-13(4-7-17(16)24)12-2-5-15(23)6-3-12;1-31-19(32)21(30-20(31)28,18-11-13(8-9-29-18)22(25,26)27)15-10-12(6-7-17(15)24)14-4-2-3-5-16(14)23;1-30-19(31)21(29-20(30)27,18-12-15(9-10-28-18)22(24,25)26)16-11-14(7-8-17(16)23)13-5-3-2-4-6-13;1-31-16(32)19(30-18(31)26,14-3-2-4-15(29-14)20(23,24)25)12-7-10(5-6-13(12)21)11-8-27-17(22)28-9-11;1-28-16(29)18(27-17(28)24,14-3-2-4-15(26-14)19(21,22)23)11-7-10(5-6-12(11)20)13-8-30-9-25-13/h2-11H,1H3,(H2,29,31);2*2-11H,1H3,(H2,28,30);2-12H,1H3,(H2,27,29);2-9H,1H3,(H2,26,30);2-9H,1H3,(H2,24,27)
InChIKeyKLAHAWFUDAMRNW-UHFFFAOYSA-N
MW2658.31 g/mol
LogP22.16
Rot. Bonds18

About 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile

2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile (PubChem CID 159165585) has the molecular formula C128H87F27N28O6S and a molecular weight of 2658.31 g/mol. Its IUPAC name is 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile.

Molecular Properties

Compound Name2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile
PubChem CID159165585
Molecular FormulaC128H87F27N28O6S
Molecular Weight2658.31 g/mol
Exact Mass2656.67
IUPAC Name2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile
SMILESCN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3ccc(F)cc3)ccc2F)N=C1N.CN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3cccc(C#N)c3)ccc2F)N=C1N.CN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3ccccc3)ccc2F)N=C1N.CN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3ccccc3F)ccc2F)N=C1N.CN1C(=O)C(c2cccc(C(F)(F)F)n2)(c2cc(-c3cnc(F)nc3)ccc2F)N=C1N.CN1C(=O)C(c2cccc(C(F)(F)F)n2)(c2cc(-c3cscn3)ccc2F)N=C1N
InChIInChI=1S/C23H15F4N5O.2C22H15F5N4O.C22H16F4N4O.C20H13F5N6O.C19H13F4N5OS/c1-32-20(33)22(31-21(32)29,19-11-16(7-8-30-19)23(25,26)27)17-10-15(5-6-18(17)24)14-4-2-3-13(9-14)12-28;1-31-19(32)21(30-20(31)28,18-11-14(8-9-29-18)22(25,26)27)16-10-13(4-7-17(16)24)12-2-5-15(23)6-3-12;1-31-19(32)21(30-20(31)28,18-11-13(8-9-29-18)22(25,26)27)15-10-12(6-7-17(15)24)14-4-2-3-5-16(14)23;1-30-19(31)21(29-20(30)27,18-12-15(9-10-28-18)22(24,25)26)16-11-14(7-8-17(16)23)13-5-3-2-4-6-13;1-31-16(32)19(30-18(31)26,14-3-2-4-15(29-14)20(23,24)25)12-7-10(5-6-13(12)21)11-8-27-17(22)28-9-11;1-28-16(29)18(27-17(28)24,14-3-2-4-15(26-14)19(21,22)23)11-7-10(5-6-12(11)20)13-8-30-9-25-13/h2-11H,1H3,(H2,29,31);2*2-11H,1H3,(H2,28,30);2-12H,1H3,(H2,27,29);2-9H,1H3,(H2,26,30);2-9H,1H3,(H2,24,27)
InChIKeyKLAHAWFUDAMRNW-UHFFFAOYSA-N
XLogP22.16
TPSA491.94 Ų
H-Bond Donors6
H-Bond Acceptors29
Rotatable Bonds18
Heavy Atoms190
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002658.31
LogP ≤ 522.16
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1029

Analyze 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile with MolForge

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Launch Full Analysis

Related Compounds

4-(1,1-difluoroethyl)-N-[4-fluoro-3-[methyl(pyrimidin-5-yl)amino]phenyl]pyridine-2-carboxamide;N-[3,4-difluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-6-methylpyridine-2-carboxamide;N-[3,4-difluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-1,3-thiazole-4-carboxamide;3-fluoro-N-[4-fluoro-3-[methyl(pyrimidin-5-yl)amino]phenyl]-6-methylpyridine-2-carboxamide;N-[4-fluoro-3-[methyl(pyrimidin-5-yl)amino]phenyl]-5-methylpyridine-2-carboxamide
CID 123938381
2-Amino-3-[[3-[2-amino-1-[[3-[2-amino-4-[6-(difluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-5-pyrimidin-5-ylphenyl]methyl]-4-[3-(difluoromethyl)phenyl]-5-oxoimidazol-4-yl]-5-pyrimidin-5-ylphenyl]methyl]-5-[6-(fluoromethyl)-3-pyridinyl]-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one
CID 142510293
2-Amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[5-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one
CID 160533477
CID 160818942
CID 160818942
2-[3,4-Difluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-1-(6-methyl-2-pyridinyl)ethanone;2-[3,4-difluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-1-(1,3-thiazol-4-yl)ethanone;2-[3-fluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-1-(6-methyl-2-pyridinyl)ethanone;2-[4-fluoro-3-[methyl(pyrimidin-5-yl)amino]phenyl]-1-(6-methyl-2-pyridinyl)ethanone;1-(3-methylphenyl)-2-[3-[methyl-[5-(trifluoromethyl)-3-pyridinyl]amino]phenyl]ethanone
CID 160853268
2-Amino-5-[6-(1,1-difluoroethyl)-3-pyridinyl]-3-methyl-5-(3-phenylphenyl)imidazol-4-one;2-amino-5-[3-(2-fluorophenyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[3-(4-fluorophenyl)phenyl]-3-methyl-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-yl]phenyl]benzonitrile;2-amino-3-methyl-5-[3-(1,3-thiazol-4-yl)phenyl]-5-[5-(trifluoromethyl)-2-pyridinyl]imidazol-4-one
CID 160884920
2-Amino-5-[2-(difluoromethyl)-4-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[6-(difluoromethyl)-3-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[2-(trifluoromethyl)-4-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-3-methyl-5-(3-pyrimidin-5-ylphenyl)-5-[6-(trifluoromethyl)-3-pyridinyl]imidazol-4-one
CID 161684540
5-[(4S,5S)-2-amino-4-[4-(3-cyanophenyl)thiophen-2-yl]-1,4-dimethyl-6-oxo-5H-pyrimidin-5-yl]pyridine-2-carbonitrile;3-[3-[(4S,5R)-2-amino-5-ethyl-1,4-dimethyl-6-oxo-5H-pyrimidin-4-yl]phenyl]benzonitrile;(5S,6S)-2-amino-6-[2-(2-fluoro-3-pyridinyl)-4-pyridinyl]-3,6-dimethyl-5-(4-phenylphenyl)-5H-pyrimidin-4-one;(5R,6S)-2-amino-6-[2-(2-fluoro-3-pyridinyl)-4-pyridinyl]-3,6-dimethyl-5-(4-phenylphenyl)-5H-pyrimidin-4-one
CID 158054195
2-Amino-5-[2,4-difluoro-5-(2-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(4-fluorophenyl)phenyl]-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(2,4-difluoro-5-phenylphenyl)-5-[4-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[2,4-difluoro-5-(1,3-thiazol-4-yl)phenyl]-5-[6-(fluoromethyl)-2-pyridinyl]-3-methylimidazol-4-one;3-[5-[2-amino-4-[4-(fluoromethyl)-2-pyridinyl]-1-methyl-5-oxoimidazol-4-yl]-2,4-difluorophenyl]benzonitrile
CID 158784276
2-Amino-5-[6-(difluoromethyl)-3-pyridinyl]-3-methyl-5-(3-pyridin-3-ylphenyl)imidazol-4-one;2-amino-5-[2-(difluoromethyl)-4-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[4-(difluoromethyl)-2-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[5-(difluoromethyl)-2-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[5-(difluoromethyl)-3-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[6-(difluoromethyl)-2-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one
CID 158989233
(7aR)-2-amino-6-(5-fluoro-2-pyridinyl)-3-methyl-7a-(4-pyrimidin-5-ylthiophen-2-yl)-5,7-dihydro-4aH-pyrrolo[3,4-d]pyrimidin-4-one;5-[5-[(7aR)-2-amino-3-methyl-6-(2-methylphenyl)-4-oxo-5,7-dihydro-4aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl]pyridine-3-carbonitrile;3-[5-[(7aR)-2-amino-3-methyl-6-(6-methyl-3-pyridinyl)-4-oxo-5,7-dihydro-4aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl]benzonitrile;3-[5-[(7aR)-2-amino-3-methyl-4-oxo-6-pyrazin-2-yl-5,7-dihydro-4aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl]benzonitrile
CID 159381007
2-Amino-5-[2-(fluoromethyl)-4-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[4-(fluoromethyl)-2-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[5-(fluoromethyl)-2-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[5-(fluoromethyl)-3-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[6-(fluoromethyl)-2-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one;2-amino-5-[6-(fluoromethyl)-3-pyridinyl]-3-methyl-5-(3-pyrimidin-5-ylphenyl)imidazol-4-one
CID 159746798

Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile?
The IUPAC name of 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile (CID 159165585) is 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile.
What is the SMILES notation for 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile?
The canonical SMILES for 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile is CN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3ccc(F)cc3)ccc2F)N=C1N.CN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3cccc(C#N)c3)ccc2F)N=C1N.CN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3ccccc3)ccc2F)N=C1N.CN1C(=O)C(c2cc(C(F)(F)F)ccn2)(c2cc(-c3ccccc3F)ccc2F)N=C1N.CN1C(=O)C(c2cccc(C(F)(F)F)n2)(c2cc(-c3cnc(F)nc3)ccc2F)N=C1N.CN1C(=O)C(c2cccc(C(F)(F)F)n2)(c2cc(-c3cscn3)ccc2F)N=C1N.
What is the InChIKey of 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile?
The InChIKey is KLAHAWFUDAMRNW-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H15F4N5O.2C22H15F5N4O.C22H16F4N4O.C20H13F5N6O.C19H13F4N5OS/c1-32-20(33)22(31-21(32)29,19-11-16(7-8-30-19)23(25,26)27)17-10-15(5-6-18(17)24)14-4-2-3-13(9-14)12-28;1-31-19(32)21(30-20(31)28,18-11-14(8-9-29-18)22(25,26)27)16-10-13(4-7-17(16)24)12-2-5-15(23)6-3-12;1-31-19(32)21(30-20(31)28,18-11-13(8-9-29-18)22(25,26)27)15-10-12(6-7-17(15)24)14-4-2-3-5-16(14)23;1-30-19(31)21(29-20(30)27,18-12-15(9-10-28-18)22(24,25)26)16-11-14(7-8-17(16)23)13-5-3-2-4-6-13;1-31-16(32)19(30-18(31)26,14-3-2-4-15(29-14)20(23,24)25)12-7-10(5-6-13(12)21)11-8-27-17(22)28-9-11;1-28-16(29)18(27-17(28)24,14-3-2-4-15(26-14)19(21,22)23)11-7-10(5-6-12(11)20)13-8-30-9-25-13/h2-11H,1H3,(H2,29,31);2*2-11H,1H3,(H2,28,30);2-12H,1H3,(H2,27,29);2-9H,1H3,(H2,26,30);2-9H,1H3,(H2,24,27).
What are the key properties of 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile?
2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile has a molecular weight of 2658.31 g/mol, XLogP of 22.16, 18 rotatable bonds, 6 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-5-[2-fluoro-5-(2-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(4-fluorophenyl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(2-fluoro-5-phenylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[2-fluoro-5-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[6-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;3-[3-[2-amino-1-methyl-5-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-yl]-4-fluorophenyl]benzonitrile is sourced from PubChem (CID 159165585), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).