6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile

C147H170ClF8N25 — CID 158789674

About 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile

6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile (PubChem CID 158789674) has the molecular formula C147H170ClF8N25 and a molecular weight of 2474.59 g/mol. Its IUPAC name is 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile.

Molecular Properties

• Compound Name: 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile
• PubChem CID: 158789674
• Molecular Formula: C147H170ClF8N25
• Molecular Weight: 2474.59 g/mol
• Exact Mass: 2472.36
• IUPAC Name: 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile
• SMILES: CC(C)N1CCCc2cc(-c3ccc(N(C)C)nc3)c(C(F)F)cc21.CC(C)N1CCCc2cc(-c3ccn(C)n3)c(C(F)F)cc21.CC(C)N1CCCc2cc(-c3ccncn3)c(C#N)cc21.CC(C)N1CCCc2cc(-c3cncc(Cl)c3)c(C(F)F)cc21.CNc1ccc(-c2cc3c(cc2C(F)F)N(C(C)C)CCC3)cn1.Cc1ccc(-c2cc3c(cc2C#N)N(C(C)C)CCC3)nc1.Cc1ccnc(-c2cc3c(cc2C#N)N(C(C)C)CCC3)c1.Cc1nn(C)cc1-c1cc2c(cc1C#N)N(C(C)C)CCC2
• InChI: InChI=1S/C20H25F2N3.C19H23F2N3.2C19H21N3.C18H19ClF2N2.C18H22N4.C17H21F2N3.C17H18N4/c1-13(2)25-9-5-6-14-10-16(17(20(21)22)11-18(14)25)15-7-8-19(23-12-15)24(3)4;1-12(2)24-8-4-5-13-9-15(16(19(20)21)10-17(13)24)14-6-7-18(22-3)23-11-14;1-13(2)22-8-4-5-15-9-17(16(11-20)10-19(15)22)18-7-6-14(3)12-21-18;1-13(2)22-8-4-5-15-10-17(16(12-20)11-19(15)22)18-9-14(3)6-7-21-18;1-11(2)23-5-3-4-12-7-15(13-6-14(19)10-22-9-13)16(18(20)21)8-17(12)23;1-12(2)22-7-5-6-14-8-16(15(10-19)9-18(14)22)17-11-21(4)20-13(17)3;1-11(2)22-7-4-5-12-9-13(15-6-8-21(3)20-15)14(17(18)19)10-16(12)22;1-12(2)21-7-3-4-13-8-15(14(10-18)9-17(13)21)16-5-6-19-11-20-16/h7-8,10-13,20H,5-6,9H2,1-4H3;6-7,9-12,19H,4-5,8H2,1-3H3,(H,22,23);6-7,9-10,12-13H,4-5,8H2,1-3H3;6-7,9-11,13H,4-5,8H2,1-3H3;6-11,18H,3-5H2,1-2H3;8-9,11-12H,5-7H2,1-4H3;6,8-11,17H,4-5,7H2,1-3H3;5-6,8-9,11-12H,3-4,7H2,1-2H3
• InChIKey: ISCQXSXAXFWBAY-UHFFFAOYSA-N
• XLogP: 34.27
• TPSA: 262.22 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 25
• Rotatable Bonds: 22
• Heavy Atoms: 181
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2474.59
LogP ≤ 5	34.27
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile?

The IUPAC name of 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile (CID 158789674) is 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile.

What is the SMILES notation for 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile?

The canonical SMILES for 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile is CC(C)N1CCCc2cc(-c3ccc(N(C)C)nc3)c(C(F)F)cc21.CC(C)N1CCCc2cc(-c3ccn(C)n3)c(C(F)F)cc21.CC(C)N1CCCc2cc(-c3ccncn3)c(C#N)cc21.CC(C)N1CCCc2cc(-c3cncc(Cl)c3)c(C(F)F)cc21.CNc1ccc(-c2cc3c(cc2C(F)F)N(C(C)C)CCC3)cn1.Cc1ccc(-c2cc3c(cc2C#N)N(C(C)C)CCC3)nc1.Cc1ccnc(-c2cc3c(cc2C#N)N(C(C)C)CCC3)c1.Cc1nn(C)cc1-c1cc2c(cc1C#N)N(C(C)C)CCC2.

What is the InChIKey of 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile?

The InChIKey is ISCQXSXAXFWBAY-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H25F2N3.C19H23F2N3.2C19H21N3.C18H19ClF2N2.C18H22N4.C17H21F2N3.C17H18N4/c1-13(2)25-9-5-6-14-10-16(17(20(21)22)11-18(14)25)15-7-8-19(23-12-15)24(3)4;1-12(2)24-8-4-5-13-9-15(16(19(20)21)10-17(13)24)14-6-7-18(22-3)23-11-14;1-13(2)22-8-4-5-15-9-17(16(11-20)10-19(15)22)18-7-6-14(3)12-21-18;1-13(2)22-8-4-5-15-10-17(16(12-20)11-19(15)22)18-9-14(3)6-7-21-18;1-11(2)23-5-3-4-12-7-15(13-6-14(19)10-22-9-13)16(18(20)21)8-17(12)23;1-12(2)22-7-5-6-14-8-16(15(10-19)9-18(14)22)17-11-21(4)20-13(17)3;1-11(2)22-7-4-5-12-9-13(15-6-8-21(3)20-15)14(17(18)19)10-16(12)22;1-12(2)21-7-3-4-13-8-15(14(10-18)9-17(13)21)16-5-6-19-11-20-16/h7-8,10-13,20H,5-6,9H2,1-4H3;6-7,9-12,19H,4-5,8H2,1-3H3,(H,22,23);6-7,9-10,12-13H,4-5,8H2,1-3H3;6-7,9-11,13H,4-5,8H2,1-3H3;6-11,18H,3-5H2,1-2H3;8-9,11-12H,5-7H2,1-4H3;6,8-11,17H,4-5,7H2,1-3H3;5-6,8-9,11-12H,3-4,7H2,1-2H3.

What are the key properties of 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile?

6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile has a molecular weight of 2474.59 g/mol, XLogP of 34.27, 22 rotatable bonds, 1 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(5-chloro-3-pyridinyl)-7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;7-(difluoromethyl)-6-(1-methylpyrazol-3-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N,N-dimethylpyridin-2-amine;5-[7-(difluoromethyl)-1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl]-N-methylpyridin-2-amine;6-(1,3-dimethylpyrazol-4-yl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(4-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;6-(5-methyl-2-pyridinyl)-1-propan-2-yl-3,4-dihydro-2H-quinoline-7-carbonitrile;1-propan-2-yl-6-pyrimidin-4-yl-3,4-dihydro-2H-quinoline-7-carbonitrile is sourced from PubChem (CID 158789674), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).